Search Results - "Ning, Xiaoxuan"
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Specific alterations in gut microbiota in patients with chronic kidney disease: an updated systematic review
Published in Renal failure (01-01-2021)“…Emerging evidence demonstrates that gut dysbiosis is implicated in the pathogenesis of chronic kidney disease (CKD) with underlying mechanisms involving…”
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The Specific Alteration of Gut Microbiota in Diabetic Kidney Diseases—A Systematic Review and Meta-Analysis
Published in Frontiers in immunology (17-06-2022)“…Background Emerging evidence indicates that gut dysbiosis is involved in the occurrence and development of diabetic kidney diseases (DKD). However, the key…”
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Twist1 regulates macrophage plasticity to promote renal fibrosis through galectin-3
Published in Cellular and molecular life sciences : CMLS (01-03-2022)“…Renal interstitial fibrosis is the pathological basis of end-stage renal disease, in which the heterogeneity of macrophages in renal microenvironment plays an…”
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Emerging role of Twist1 in fibrotic diseases
Published in Journal of cellular and molecular medicine (01-03-2018)“…Epithelial–mesenchymal transition (EMT) is a pathological process that occurs in a variety of diseases, including organ fibrosis. Twist1, a basic…”
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A Comparative Study of the Gut Microbiota Associated With Immunoglobulin a Nephropathy and Membranous Nephropathy
Published in Frontiers in cellular and infection microbiology (20-10-2020)“…The pathogenesis of immunoglobulin A nephropathy (IgAN) and membranous nephropathy (MN) is characterized by immune dysregulation, which is related to gut…”
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CircRNAs: versatile players and new targets in organ fibrosis
Published in Cell communication and signaling (02-05-2023)“…Organ fibrosis can occur in virtually all major organs with relentlessly progressive and irreversible progress, ultimately resulting in organ dysfunction and…”
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Hypoxia‐inducible factor‐1α contributes to hypoxia‐induced chemoresistance in gastric cancer
Published in Cancer science (01-01-2008)“…Hypoxia induced drug resistance is a major obstacle in the development of effective cancer therapy. Our previous study revealed that hypoxia‐inducible factor‐1…”
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Hypoxia-induced Bmi1 promotes renal tubular epithelial cell-mesenchymal transition and renal fibrosis via PI3K/Akt signal
Published in Molecular biology of the cell (01-09-2014)“…Hypoxia is an important microenvironmental factor in the development of renal fibrosis; however, the underlying mechanisms are not well elucidated. Here we…”
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Rare complication of cushing’s syndrome in the elderly: a case report
Published in Endocrine (01-11-2021)“…Purpose Cushing’s syndrome (CS) is a rare and severe disease caused by sustained hypercortisolism. The clinical manifestations of CS can be atypical in the…”
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Roles of Twist1 in lipid and glucose metabolism
Published in Cell communication and signaling (02-10-2023)“…Abstract The abnormal lipid and glucose metabolisms are linked to the metabolic disorders, tumorigenesis, and fibrotic diseases, which attracts the increasing…”
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Specific alterations of gut microbiota in patients with membranous nephropathy: A systematic review and meta-analysis
Published in Frontiers in physiology (01-11-2022)“…Background: The pathogenesis of idiopathic membranous nephropathy (IMN) has not yet been thoroughly clarified, and gut dysbiosis may be a contributor to IMN…”
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Cell Profiling of Acute Kidney Injury to Chronic Kidney Disease Reveals Novel Oxidative Stress Characteristics in the Failed Repair of Proximal Tubule Cells
Published in International journal of molecular sciences (01-07-2023)“…Chronic kidney disease (CKD) is a major public health issue around the world. A significant number of CKD patients originates from acute kidney injury (AKI)…”
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Histone deacetylases: potential therapeutic targets in cisplatin-induced acute kidney injury
Published in Annals of medicine (Helsinki) (01-12-2024)“…Chemotherapy has been well shown to enhance life expectancy in patients with malignancy. However, conventional chemotherapy drugs, particularly cisplatin, are…”
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Hypoxia-inducible factor-1α induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition
Published in Kidney international (01-06-2009)“…Epithelial-to-mesenchymal transition (EMT) induced by chronic hypoxia is one of the critical causes of renal fibrosis. Twist, a basic helix-loop-helix…”
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MicroRNA‐493 targets STMN‐1 and promotes hypoxia‐induced epithelial cell cycle arrest in G2/M and renal fibrosis
Published in The FASEB journal (01-02-2019)“…ABSTRACT Hypoxia plays an important role in the development of renal fibrosis. G2/M arrest in renal tubular cells is an important pathway in the development of…”
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Exploring the crosstalk molecular mechanisms between IgA nephropathy and Sjögren’s syndrome based on comprehensive bioinformatics and immunohistochemical analyses
Published in Clinical and experimental medicine (13-08-2024)“…IgA nephropathy (IgAN) and Sjogren's syndrome (SS) are two autoimmune diseases with undetermined etiology and related to abnormal activation of lymphocytes…”
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Sex-specific effects of aging on humoral immune responses to repeated influenza vaccination in older adults
Published in npj vaccines (09-12-2021)“…Older adults (≥65 years of age) bear a significant burden of severe disease and mortality associated with influenza, despite relatively high annual vaccination…”
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Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis
Published in Frontiers in immunology (19-10-2022)“…Emerging evidence revealed that gut microbial dysbiosis is implicated in the development of plasma cell dyscrasias and amyloid deposition diseases, but no data…”
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Alterations of the gut microbiota in the lupus nephritis: a systematic review
Published in Renal failure (2023)“…Emerging evidence suggests that gut microbiota dysbiosis may play a critical role in the development of lupus nephritis (LN). However, the specific…”
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Egr-1 mediates chronic hypoxia-induced renal interstitial fibrosis via the PKC/ERK pathway
Published in American journal of nephrology (01-01-2014)“…Chronic hypoxia-induced epithelial-to-mesenchymal transition (EMT) is a crucial process in renal fibrogenesis. Egr-1, as a transcription factor, has been…”
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