Search Results - "Nines, Ronald"
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Photochemoprevention of UVB‐induced skin carcinogenesis in SKH‐1 mice by brown algae polyphenols
Published in International journal of cancer (15-12-2006)“…Chronic exposure of the skin to ultraviolet B (UVB) radiation induces oxidative stress, which plays a crucial role in the induction of skin cancer. In this…”
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Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun
Published in Cancer research (Chicago, Ill.) (01-03-2006)“…Our laboratory has used a rodent model of human esophageal squamous cell carcinoma to identify putative chemopreventive agents for this disease and to…”
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Black raspberries inhibit N-nitrosomethylbenzylamine (NMBA)-induced angiogenesis in rat esophagus parallel to the suppression of COX-2 and iNOS
Published in Carcinogenesis (New York) (01-11-2006)“…Angiogenesis, the formation of new blood vessels, is critical to tumor growth and metastasis. Vascular endothelial growth factor (VEGF), an important…”
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Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-05-2004)“…The inducible nitric oxide synthase (iNOS) generates a high concentration of nitric oxide (NO) in tissues. Increased NO production is associated with many…”
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In situ Assessment of Intraepithelial Neoplasia in Hamster Trachea Epithelium Using Angle-Resolved Low-Coherence Interferometry
Published in Cancer epidemiology, biomarkers & prevention (01-02-2007)“…Optical spectroscopy was used to evaluate the transformation of nuclear morphology associated with intraepithelial neoplasia in an animal model of…”
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Abstract 3686: Microarray analysis of dynamic regulation of genes in early and late stages of chemically induced esophageal carcinogenesis in rats
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Esophageal carcinogenesis is a multistage process characterized by morphological changes from normal esophagus to basal cell hyperplasia, dysplasia,…”
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Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms
Published in Nutrition and cancer (2006)“…For several years, our laboratory has been evaluating the ability of lyophilized (freeze-dried) black raspberries (Rubus occidentalis, BRBs), blackberries (R…”
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Abstract 1624: Black raspberries suppress phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway in carcinogen-induced esophageal cancer in rats
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Esophageal squamous cell carcinoma (SCC) is one of the most common malignant neoplasms worldwide. The overall 5-year survival rate of esophageal SCC…”
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Abstract LB-462: Chemopreventive effects of freeze-dried strawberries in inflammation-associated mouse colon tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Colorectal cancer (CRC) is one of the most common malignant neoplasms in the United States. The risk for CRC is associated with extent and duration of…”
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In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry
Published in Cancer research (Chicago, Ill.) (01-07-2003)“…We present a quantitative study of the nuclear morphometry of epithelial cells in an animal model of esophageal carcinogenesis. Changes in the size and texture…”
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Abstract 819: Black raspberries inhibit N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis through down-regulation of MAPK and NFκB pathways
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Esophageal cancer is the 6th most common cancer worldwide. Our laboratory has used a rodent preclinical model of esophageal squamous cell carcinoma to…”
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Abstract 811: Co-inhibition of cyclooxygenase-2 and inducible nitric oxide synthase prevents N-nitrosomethylbenzylamine-induced esophageal squamous cell carcinoma in rats
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Hyperactivation of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) has been observed separately in esophageal squamous cell…”
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Abstract LB-423: Combined chemopreventive effects of selective inducible nitric oxide synthase and cyclooxygenase-2 inhibitors on N -Nitrosomethylbenzylamine-induced rat esophageal tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Esophageal cancer is the 6th most common cancer worldwide. Our laboratory has used a rodent preclinical model of esophageal squamous cell carcinoma to…”
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Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry
Published in Journal of biomedical optics (01-09-2005)“…Angle-resolved low-coherence interferometry (a/LCI) is used to obtain quantitative, depth-resolved nuclear morphology measurements. We compare the average…”
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Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus
Published in Cancer research (Chicago, Ill.) (01-07-2007)“…There is little information on early molecular events in the development of N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis and of the…”
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Prevention of mouse lung tumors by targretin
Published in International journal of cancer (01-05-2006)“…Targretin has indicated chemotherapeutic activity against nonsmall‐cell lung cancer and chemoprevention in rat mammary gland. Therefore, targretin was…”
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Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-05-2003)“…Perillyl alcohol (POH) is a monoterpene found in lavender, spearmint, and cherries. Phase I clinical trials with this agent have shown a favorable toxicity…”
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