Search Results - "Nimura, Yoshinori"
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Cloning and functional analysis of human p51 , which structurally and functionally resembles p53
Published in Nature medicine (01-07-1998)“…The p53 tumor suppressor gene, which is induced by DNA damage and/or stress stimuli, causes cells to undergo G1-arrest or apoptotic death; thus it plays an…”
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2
Cathepsin D is a potential serum marker for poor prognosis in glioma patients
Published in Cancer research (Chicago, Ill.) (15-06-2005)“…Cathepsin D is an aspartyl protease involved in protein catabolism and tissue remodeling which can be secreted from cancer cells. To identify a potential serum…”
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3
Relationship Between Pancreatic Secretory Trypsin Inhibitor and Early Recurrence of Intrahepatic Cholangiocarcinoma Following Surgical Resection
Published in The American journal of gastroenterology (01-07-2006)“…The extremely unfavorable prognosis of intrahepatic cholangiocarcinoma (ICC), even after surgical resection, is mainly attributed to a high rate of recurrence…”
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4
Silencing Ku80 using small interfering RNA enhanced radiation sensitivity in vitro and in vivo
Published in International journal of oncology (01-06-2007)“…Ku80 is an important component of DNA double-strand break repair, and Ku80 deficiency leads to extreme sensitivity to ionizing radiation. We studied whether…”
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5
p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent
Published in Oncogene (28-01-1999)“…p73, a novel p53 family member, is a recently identified candidate neuroblastoma (NBL) suppressor gene mapped at chromosome 1p36.33 and was found to inhibit…”
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6
Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina
Published in Experimental eye research (01-10-2006)“…Diabetic retinopathy is one of the most frequent complications of diabetes and is a leading cause of vision loss in adulthood. To better understand the…”
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7
Long-term survival in a case of recurrent gastrointestinal stromal tumor treated with intermittent or low-dose imatinib
Published in Gan to kagaku ryoho (01-03-2014)“…A 65-year-old woman with a gastrointestinal stromal tumor(GIST)underwent a total gastrectomy in 1999. In 2004, she was diagnosed with an intra-abdominal…”
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8
Allelic Loss of the Region of Chromosome 1p35‐pter Is Associated with Progression of Human Gastric Carcinoma
Published in Cancer science (01-08-2000)“…In order to identify the region on distal chromosome 1p that is thought to include one or more tumor suppressor genes for gastric carcinoma, 39 gastric…”
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9
Reresection for local recurrence of rectal cancer
Published in Surgery today (Tokyo, Japan) (01-01-1999)“…Local recurrence is one of the major reasons that rectal cancer surgery is unsuccessful. The aim of this study was to investigate the surgical characteristics…”
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10
Giant cavernous hemangioma of the liver: is tumor size a risk factor for hepatectomy?
Published in Journal of Hepato‐Biliary‐Pancreatic Surgery (1999)“…The aim of this study was to evaluate whether hepatic giant cavernous hemangioma (GCH) tumor size is a risk factor for hepatectomy. Twenty patients with GCH of…”
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11
The influence of excess body weight on the surgical treatment of patients with gastric cancer
Published in Surgery today (Tokyo, Japan) (01-11-1995)“…Sixty-two overweight gastric cancer patients were compared with 201 normal-weight patients to clarify the influences of excessive weight on the surgical…”
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12
Germline mutations of the APC gene in two Japanese adenomatous polyposis patients
Published in Journal of human genetics (01-09-1997)“…Germline mutations of the adenomatous polyposis coli (APC) gene have been reported in patients with familial adenomatous polyposis (FAP) and are believed to be…”
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13
Identification of genes associated with multiple nodules in hepatocellular carcinoma using cDNA microarray: multicentric occurrence or intrahepatic metastasis?
Published in Hepato-gastroenterology (01-05-2008)“…The prognosis of hepatocellular carcinoma (HCC) is poor because of frequent intrahepatic metastasis (IM) or multicentric carcinogenesis (MC). This study…”
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14
Multiple carcinoids of the duodenum accompanied by type I familial multiple endocrine neoplasia
Published in Surgery today (Tokyo, Japan) (01-01-1998)“…A case of multiple carcinoid tumors of the duodenum accompanied by familial multiple endocrine neoplasia is reported. A 46-year-old man with duodenal polyps…”
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15
Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2009)“…Abstract While lymph node metastasis is a major factor associated with poor prognosis in cancer, little is known of its molecular mechanisms. The aim of this…”
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16
Mutation, allelotyping, and transcription analyses of the p73 gene in prostatic carcinoma
Published in Cancer research (Chicago, Ill.) (15-05-1998)“…A novel gene, p73, encoding a protein with significant homology to p53, was recently identified at 1p36. To investigate penetrance of p73 in prostatic…”
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17
Chromosome 1 open reading frame 10 ( C1orf10) gene is frequently down-regulated and inhibits cell proliferation in oral squamous cell carcinoma
Published in The international journal of biochemistry & cell biology (01-08-2005)“…Chromosome 1 open reading frame 10 ( C1orf10) is a recently identified gene encoding a protein with an S100 EF-hand calcium-binding motif, and its expression…”
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18
Identification of candidate radioresistant genes in human squamous cell carcinoma cells through gene expression analysis using DNA microarrays
Published in Oncology reports (01-11-2005)“…Radiation therapy is currently the standard adjuvant approach for oral squamous cell carcinoma (OSCC) patients. Individual OSCCs display a wide range of…”
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19
Arpc1b Gene Is a Candidate Prediction Marker for Choroidal Malignant Melanomas Sensitive to Radiotherapy
Published in Investigative ophthalmology & visual science (01-06-2006)“…Choroidal malignant melanomas (CMMs) are the most common primary intraocular tumors in adult humans. Although radiotherapy is commonly used to treat the…”
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S100A11 gene identified by in-house cDNA microarray as an accurate predictor of lymph node metastases of gastric cancer
Published in Oncology reports (01-06-2004)“…Gastric cancer is one of the most common malignancies in the world, and in Asian countries its incidence and mortality rates are very high. Worldwide, Japan…”
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