Search Results - "Nilsson, Jesper R"
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1
Characterization of the Thermal and Photoinduced Reactions of Photochromic Spiropyrans in Aqueous Solution
Published in The journal of physical chemistry. B (31-10-2013)“…Six water-soluble spiropyran derivatives have been characterized with respect to the thermal and photoinduced reactions over a broad pH-interval. A…”
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Journal Article -
2
Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleoside phosphate analogues
Published in Nucleic acids research (20-08-2024)“…RNA and its building blocks play central roles in biology and have become increasingly important as therapeutic agents and targets. Hence, probing and…”
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3
Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors
Published in Scientific reports (06-05-2015)“…REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase required for normal development and maintenance of neurons of the central and…”
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4
Interbase FRET in RNA: from A to Z
Published in Nucleic acids research (04-11-2019)“…Abstract Interbase FRET can reveal highly detailed information about distance, orientation and dynamics in nucleic acids, complementing the existing structure…”
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5
Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor
Published in Nucleic acids research (20-08-2020)“…Abstract With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving…”
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6
Fluorescent base analogues in gapmers enable stealth labeling of antisense oligonucleotide therapeutics
Published in Scientific reports (31-05-2021)“…To expand the antisense oligonucleotide (ASO) fluorescence labeling toolbox beyond covalent conjugation of external dyes ( e.g. ATTO-, Alexa Fluor-, or cyanine…”
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Journal Article -
7
Interbase-FRET binding assay for pre-microRNAs
Published in Scientific reports (30-04-2021)“…The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of…”
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8
Light-induced cytotoxicity of a photochromic spiropyran
Published in Chemical communications (Cambridge, England) (01-01-2011)“…In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant…”
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9
8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction
Published in PloS one (05-05-2015)“…Small molecule nonpeptidic mimics of α-helices are widely recognised as protein-protein interaction (PPIs) inhibitors. Protein-protein interactions mediate…”
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Journal Article -
10
An All-Photonic Molecule-Based Parity Generator/Checker for Error Detection in Data Transmission
Published in Journal of the American Chemical Society (17-07-2013)“…The function of a parity generator/checker, which is an essential operation for detecting errors in data transmission, has been realized with multiphotochromic…”
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Journal Article -
11
Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery
Published in Journal of the American Chemical Society (14-04-2021)“…Methods for tracking RNA inside living cells without perturbing their natural interactions and functions are critical within biology and, in particular, to…”
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Journal Article -
12
DNA-Binding Properties of Amidine-Substituted Spiropyran Photoswitches
Published in Chemistry : a European journal (24-11-2014)“…Two amidine‐substituted spiropyran derivatives have been characterized with respect to the DNA‐binding properties over a broad pH interval. The two derivatives…”
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13
A photoswitchable supramolecular complex with release-and-report capabilities
Published in Chemical communications (Cambridge, England) (18-01-2015)“…A self-assembled supramolecular platform has been designed for reversibly controlling the concentration of a compound in solution, via a photochemical…”
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14
A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos
Published in Scientific reports (24-08-2015)“…Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems…”
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15
Switching Properties of a Spiropyran-Cucurbit[7]uril Supramolecular Assembly: Usefulness of the Anchor Approach
Published in Chemphyschem (12-11-2012)“…A nitrospiropyran, which was modified with a cadaverine‐derived anchor, was investigated with respect to its thermally induced isomerizations, hydrolytic…”
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16
Stealth fluorescence labeling for live microscopy imaging of mRNA delivery
Published in Journal of the American Chemical Society (02-04-2021)“…Methods for tracking RNA molecules inside living cells without perturbing their natural interactions and functions are critical within biology and, in…”
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Journal Article -
17
Development of functionalized SYBR green II related cyanine dyes for viral RNA detection
Published in Dyes and pigments (01-06-2020)“…Fluorescent probes for sensing nucleic acids have found widespread use in the field of cell and molecular biology. However, probes combined with potential for…”
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18
All-Photonic Control of Biorelevant Processes using Molecular Photoswitches and Caged Compounds
Published 01-01-2015“…The development of light-controlled molecular tools for in situ regulation of biological activity holds great promise e.g. for resolving dynamic aspects of…”
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Dissertation -
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8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction: e0124423
Published in PloS one (01-05-2015)“…Small molecule nonpeptidic mimics of alpha -helices are widely recognised as protein-protein interaction (PPIs) inhibitors. Protein-protein interactions…”
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Journal Article