Search Results - "Nilsson, Elise"
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Isolation and Characterization of Progenitor-Like Cells from Human Renal Proximal Tubules
Published in The American journal of pathology (01-02-2011)“…The tubules of the kidney display a remarkable capacity for self-renewal on damage. Whether this regeneration is mediated by dedifferentiating surviving cells…”
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2
FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function
Published in The EMBO journal (16-11-2011)“…Exposure of metazoan organisms to hypoxia engages a metabolic switch orchestrated by the hypoxia‐inducible factor 1 (HIF‐1). HIF‐1 mediates induction of…”
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3
Sarcomatoid conversion of clear cell renal cell carcinoma in relation to epithelial-to-mesenchymal transition
Published in Human pathology (01-05-2012)“…Summary Approximately 8% of clear cell renal cell carcinoma cases contain regions of radically different morphology, demonstrating a mesenchymal appearance…”
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4
Multiple Cellular Mechanisms Related to Cyclin A1 in Prostate Cancer Invasion and Metastasis
Published in JNCI : Journal of the National Cancer Institute (16-07-2008)“…Background Cyclin A1 is a cell cycle regulator that has been implicated in the progression of prostate cancer. Its role in invasion and metastasis of this…”
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5
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients
Published in BMC cancer (17-09-2010)“…There is an insufficient number of reliable prognostic and response predictive biomarkers in colorectal cancer (CRC) management. In a previous study, we found…”
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6
Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival
Published in Journal of ovarian research (17-06-2010)“…Altered androgen hormone homeostasis and androgen receptor (AR) activity have been implicated in ovarian carcinogenesis but the relationship between AR…”
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7
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
Published in The Journal of clinical investigation (01-01-2008)“…Loss of the tumor suppressor gene von Hippel-Lindau (VHL) plays a key role in the oncogenesis of clear cell renal cell carcinoma (CCRCC). The loss leads to…”
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8
Local expression of complement factor I in breast cancer cells correlates with poor survival and recurrence
Published in Cancer Immunology, Immunotherapy (01-04-2015)“…Tumor cells often evade killing by the complement system by overexpressing membrane-bound complement inhibitors. However, production of soluble complement…”
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9
Therapeutic Targeting of Nuclear γ‐tubulin in RB1‐negative Tumors
Published in The FASEB journal (01-04-2015)“…Abstract only Reduced protein levels of nuclear γ‐tubulin increase the transcriptional activities of E2Fs and raise the protein levels of Retinoblastoma (RB1)…”
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10
Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors
Published in Molecular cancer research (01-07-2015)“…In addition to its cytosolic function, γ-tubulin is a chromatin-associated protein. Reduced levels of nuclear γ-tubulin increase the activity of E2…”
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Lena Sjöstrand, Mer än tecken. Atmosfär, betydelser och liturgiska kroppar
Published in Svensk teologisk kvartalskrift (01-10-2014)Get full text
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Tumors with Nonfunctional Retinoblastoma Protein Are Killed by Reduced γ-Tubulin Levels
Published in The Journal of biological chemistry (18-05-2012)“…In various tumors inactivation of growth control is achieved by interfering with the RB1 signaling pathway. Here, we describe that RB1 and γ-tubulin proteins…”
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13
Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ
Published in Cancer research (Chicago, Ill.) (01-04-2003)“…In cultured neuroblastoma cells, hypoxia induces a dedifferentiated phenotype. We tested whether hypoxia-induced dedifferentiation also occurs in vivo in…”
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Abstract 3439: Sarcomatoid renal cell carcinoma as a biological example of epithelial to mesenchymal transition (EMT)
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract About 8% of clear cell renal cell carcinoma (CCRCC) cases contain areas of a radically different morphology, demonstrating spindle shaped cells and a…”
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15
Tumors with non-functional RB1 are killed by reduced gamma-tubulin levels
Published in The Journal of biological chemistry (2012)“…In various tumors inactivation of growth control is achieved by interfering with the RB1 signaling pathway. Here, we describe that RB1 and γ tubulin proteins…”
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16
Expression of serotonin receptors and role of serotonin in human prostate cancer tissue and cell lines
Published in The Prostate (15-05-2004)“…BACKGROUND Increase in the number of serotonin (5‐HT) releasing neuroendocrine (NE) cells has been shown to be correlated with tumor progression, loss of…”
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17
FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function: FoxO3A inhibits Myc to control hypoxic metabolism
Published in The EMBO journal (16-11-2011)Get full text
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18
The Bcl‐xL inhibitor of apoptosis is preferentially expressed in cutaneous squamous cell carcinoma compared with that in keratoacanthoma
Published in International journal of cancer (15-05-2009)“…Keratoacanthoma (KA) is difficult to histologically distinguish from squamous cell carcinoma (SCC). Therefore, although KA is a benign self‐resolving skin…”
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ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERα : a combination therapy potentially targeting hypoxic and dormant tumor cells
Published in Oncogene (13-10-2005)“…Tumor hypoxia is associated with cancer invasiveness, metastasis and treatment failure. Recent data suggest that the major target for endocrine treatment in…”
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ERK1 2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ER : a combination therapy potentially targeting hypoxic and dormant tumor cells
Published in Oncogene (13-10-2005)“…Tumor hypoxia is associated with cancer invasiveness, metastasis and treatment failure. Recent data suggest that the major target for endocrine treatment in…”
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