Search Results - "Nilsen, Nadra"

Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness by Bugge, Marit, Bergstrom, Bjarte, Eide, Oda K., Solli, Helene, Kjønstad, Ingrid F., Stenvik, Jørgen, Espevik, Terje, Nilsen, Nadra J.

“…Toll-like receptors (TLRs) are innate immune receptors for sensing microbial molecules and damage-associated molecular patterns released from host cells…”
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A Role for the Adaptor Proteins TRAM and TRIF in Toll-like Receptor 2 Signaling by Nilsen, Nadra J., Vladimer, Gregory I., Stenvik, Jørgen, Orning, M. Pontus A., Zeid-Kilani, Maria V., Bugge, Marit, Bergstroem, Bjarte, Conlon, Joseph, Husebye, Harald, Hise, Amy G., Fitzgerald, Katherine A., Espevik, Terje, Lien, Egil

“…Toll-like receptors (TLRs) are involved in sensing invading microbes by host innate immunity. TLR2 recognizes bacterial lipoproteins/lipopeptides, and…”
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The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes by Husebye, Harald, Aune, Marie Hjelmseth, Stenvik, Jørgen, Samstad, Eivind, Skjeldal, Frode, Halaas, Øyvind, Nilsen, Nadra J., Stenmark, Harald, Latz, Eicke, Lien, Egil, Mollnes, Tom Eirik, Bakke, Oddmund, Espevik, Terje

“…Toll-like receptor 4 (TLR4) is indispensable for recognition of Gram-negative bacteria. We described a trafficking pathway for TLR4 from the endocytic…”
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TLR9 signals after translocating from the ER to CpG DNA in the lysosome by Espevik, Terje, Monks, Brian G, Golenbock, Douglas T, Latz, Eicke, Knetter, Cathrine F, Nilsen, Nadra J, Lien, Egil, Visintin, Alberto, Fitzgerald, Katherine A, Schoenemeyer, Annett

“…Microbial DNA sequences containing unmethylated CpG dinucleotides activate Toll-like receptor 9 (TLR9). We have found that TLR9 is localized to the endoplasmic…”
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Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36 by Nilsen, Nadra J., Deininger, Susanne, Nonstad, Unni, Skjeldal, Frode, Husebye, Harald, Rodionov, Dmitrii, Aulock, Sonja, Hartung, Thomas, Lien, Egil, Bakke, Oddmund, Espevik, Terje

“…Lipoteichoic acid (LTA) is a central inducer of inflammatory responses caused by Gram‐positive bacteria, such as Staphylococcus aureus, via activation of TLR2…”
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Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation by Ostvik, Ann E, Granlund, Atle V B, Bugge, Marit, Nilsen, Nadra J, Torp, Sverre H, Waldum, Helge L, Damås, Jan K, Espevik, Terje, Sandvik, Arne K

“…We explored the gene expression in colonic biopsies of active and inactive inflammatory bowel disease (IBD) in an extensive material of ulcerative colitis (UC)…”
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Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1 by Manukyan, Maria, Triantafilou, Kathy, Triantafilou, Martha, Mackie, Alan, Nilsen, Nadra, Espevik, Terje, Wiesmüller, Karl‐Heinz, Ulmer, Artur J., Heine, Holger

“…Lipoproteins or lipopeptides (LP) are bacterial cell wall components detected by the innate immune system. For LP, it has been shown that TLR2 is the essential…”
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Biochemical analysis of the processive mechanism for epimerization of alginate by mannuronan C-5 epimerase AlgE4 by Campa, Cristiana, Holtan, Synnøve, Nilsen, Nadra, Bjerkan, Tonje M, Stokke, Bjørn T, Skjåk-Braek, Gudmund

“…The enzymes mannuronan C-5 epimerases catalyse the in-chain epimerisation of beta-D-mannuronic acid to alpha-L-guluronic acid in the last step of alginate…”
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Caspase‐8 regulates the expression of pro‐ and anti‐inflammatory cytokines in human bone marrow‐derived mesenchymal stromal cells by Moen, Siv H., Westhrin, Marita, Zahoor, Muhammad, Nørgaard, Nikolai N., Hella, Hanne, Størdal, Berit, Sundan, Anders, Nilsen, Nadra J., Sponaas, Anne‐Marit, Standal, Therese

“…Introduction Mesenchymal stem cells, also called mesenchymal stromal cells, MSCs, have great potential in stem cell therapy partly due to their…”
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Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88 by Nilsen, Nadra, Nonstad, Unni, Khan, Naseema, Knetter, Cathrine F., Akira, Shizuo, Sundan, Anders, Espevik, Terje, Lien, Egil

“…Toll-like receptor 2 (TLR2) is a signaling receptor for a variety of microbial products, including bacterial lipoproteins and peptidoglycan, and is central in…”
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A Proviral Role for CpG in Cytomegalovirus Infection by Iversen, Ann-Charlotte, Steinkjer, Bjorg, Nilsen, Nadra, Bohnhorst, Janne, Moen, Siv Helen, Vik, Randi, Stephens, Phil, Thomas, David W, Benedict, Chris A, Espevik, Terje

“…TLR9-dependent signaling in plasmacytoid dendritic cells is a key contributor to innate immune defense to mouse CMV infection. We aimed to study the expression…”
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Cutting Edge: Link Between Innate and Adaptive Immunity: Toll-Like Receptor 2 Internalizes Antigen for Presentation to CD4+ T Cells and Could Be an Efficient Vaccine Target by Schjetne, Karoline W, Thompson, Keith M, Nilsen, Nadra, Flo, Trude H, Fleckenstein, Burkhard, Iversen, Jens-Gustav, Espevik, Terje, Bogen, Bjarne

“…An ideal vaccine for induction of CD4(+) T cell responses should induce local inflammation, maturation of APC, and peptide loading of MHC class II molecules…”
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