Search Results - "Nilsen, Gro"

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation by Nilsen, Gro, Liestøl, Knut, Van Loo, Peter, Moen Vollan, Hans Kristian, Eide, Marianne B, Rueda, Oscar M, Chin, Suet-Feung, Russell, Roslin, Baumbusch, Lars O, Caldas, Carlos, Børresen-Dale, Anne-Lise, Lingjaerde, Ole Christian

“…Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA. The growing variety of tools for measuring genomic…”
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Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors by Cheng, Jiqiu, Demeulemeester, Jonas, Wedge, David C., Vollan, Hans Kristian M., Pitt, Jason J., Russnes, Hege G., Pandey, Bina P., Nilsen, Gro, Nord, Silje, Bignell, Graham R., White, Kevin P., Børresen-Dale, Anne-Lise, Campbell, Peter J., Kristensen, Vessela N., Stratton, Michael R., Lingjærde, Ole Christian, Moreau, Yves, Van Loo, Peter

“…Homozygous deletions are rare in cancers and often target tumour suppressor genes. Here, we build a compendium of 2218 primary tumours across 12 human cancer…”
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Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection by Sveen, Anita, Løes, Inger Marie, Alagaratnam, Sharmini, Nilsen, Gro, Høland, Maren, Lingjærde, Ole Christian, Sorbye, Halfdan, Berg, Kaja Christine Graue, Horn, Arild, Angelsen, Jon-Helge, Knappskog, Stian, Lønning, Per Eystein, Lothe, Ragnhild A

“…Chromosomal instability is a well-defined hallmark of tumor aggressiveness and metastatic progression in colorectal cancer. The magnitude of genetic…”
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Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors by Bjaanæs, Maria Moksnes, Nilsen, Gro, Halvorsen, Ann Rita, Russnes, Hege G., Solberg, Steinar, Jørgensen, Lars, Brustugun, Odd Terje, Lingjærde, Ole Christian, Helland, Åslaug

“…Abstract Background Genetic alterations are common in non-small cell lung cancer (NSCLC), and DNA mutations and translocations are targets for therapy. Copy…”
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Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors by Cheng, Jiqiu, Demeulemeester, Jonas, Wedge, David C., Vollan, Hans Kristian M., Pitt, Jason J., Russnes, Hege G., Pandey, Bina P., Nilsen, Gro, Nord, Silje, Bignell, Graham R., White, Kevin P., Børresen-Dale, Anne-Lise, Campbell, Peter J., Kristensen, Vessela N., Stratton, Michael R., Lingjærde, Ole Christian, Moreau, Yves, Van Loo, Peter

“…The original version of this Article omitted a declaration from the competing interests statement, which should have included the following: ‘K.P.W. is…”
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Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors by Cheng, Jiqiu, Demeulemeester, Jonas, Wedge, David C., Vollan, Hans Kristian M., Pitt, Jason J., Russnes, Hege G., Pandey, Bina P., Nilsen, Gro, Nord, Silje, Bignell, Graham R., White, Kevin P., Børresen-Dale, Anne-Lise, Campbell, Peter J., Kristensen, Vessela N., Stratton, Michael R., Lingjærde, Ole Christian, Moreau, Yves, Van Loo, Peter

“…The original version of this Article contained an error in the author affiliations. The affiliation of Kevin P. White with Tempus Labs, Inc., Chicago, IL, USA…”
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DNA copy number motifs are strong and independent predictors of survival in breast cancer by Pladsen, Arne V., Nilsen, Gro, Rueda, Oscar M., Aure, Miriam R., Borgan, Ørnulf, Liestøl, Knut, Vitelli, Valeria, Frigessi, Arnoldo, Langerød, Anita, Mathelier, Anthony, Engebråten, Olav, Kristensen, Vessela, Wedge, David C., Van Loo, Peter, Caldas, Carlos, Børresen-Dale, Anne-Lise, Russnes, Hege G., Lingjærde, Ole Christian

“…Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal…”
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Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas by Hoff, Andreas M, Kraggerud, Sigrid M, Alagaratnam, Sharmini, Berg, Kaja C G, Johannessen, Bjarne, Høland, Maren, Nilsen, Gro, Lingjærde, Ole C, Andrews, Peter W, Lothe, Ragnhild A, Skotheim, Rolf I

“…Testicular germ cell tumours (TGCTs) appear as different histological subtypes or mixtures of these. They show similar, multiple DNA copy number changes, where…”
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Identifying clusters in genomics data by recursive partitioning by Nilsen, Gro, Borgan, Ornulf, Liestøl, Knut, Lingjærde, Ole Christian

“…Genomics studies frequently involve clustering of molecular data to identify groups, but common clustering methods such as K-means clustering and hierarchical…”
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High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer by Mathiesen, Randi R., Fjelldal, Renathe, Liestøl, Knut, Due, Eldri U., Geigl, Jochen B., Riethdorf, Sabine, Borgen, Elin, Rye, Inga H., Schneider, Ida J., Obenauf, Anna C., Mauermann, Oliver, Nilsen, Gro, Christian Lingjærde, Ole, Børresen-Dale, Anne-Lise, Pantel, Klaus, Speicher, Michael R., Naume, Bjørn, Baumbusch, Lars O.

“…The presence of disseminated tumor cells (DTCs) in bone marrow (BM) identifies breast cancer patients with less favorable outcome. Furthermore, molecular…”
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Intra-individual genetic heterogeneity among liver metastases in metastatic colorectal cancer by Sveen, Anita, Loes, Inger Marie, Alagaratnam, Sharmini, Nilsen, Gro, Høland, Maren, Lingjaerde, Ole Christian, Sorbye, Halfdan, Berg, Kaja Christine Graue, Horn, Arild, Angelsen, Jon-Helge, Knappskog, Stian, Lonning, Per Eystein, Lothe, Ragnhild A

“…Abstract only 555 Background: Almost 50% of patients with colorectal cancer (CRC) develop liver metastases, often as multiple simultaneous metastatic deposits…”
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The importance of gene-centring microarray data by Sørlie, Therese, Borgan, Eldrid, Myhre, Simen, Vollan, Hans Kristian, Russnes, Hege, Zhao, Xi, Nilsen, Gro, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Rødland, Einar

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The importance of gene-centring microarray data/Authors' reply by Sørlie, Therese, Borgan, Eldrid, Myhre, Simen, Vollan, Hans Kristian, Russnes, Hege, Zhao, Xi, Nilsen, Gro, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Rødland, Einar, Weigelt, Britta, Mackay, Alan, Natrajan, Rachael, Tan, David S P, Dowsett, Mitch, Ashworth, Alan, Reis-Filho, Jorge S

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Analyzing cancer samples with SNP arrays by Van Loo, Peter, Nilsen, Gro, Nordgard, Silje H, Vollan, Hans Kristian Moen, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Lingjærde, Ole Christian

“…Single nucleotide polymorphism (SNP) arrays are powerful tools to delineate genomic aberrations in cancer genomes. However, the analysis of these SNP array…”
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