Search Results - "Nilius, Angela"

No Need for Lopinavir Dose Adjustment during Pregnancy: a Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Nonpregnant HIV-Infected Subjects by Salem, Ahmed Hamed, Jones, Aksana Kaefer, Santini-Oliveira, Marilia, Taylor, Graham P, Patterson, Kristine B, Nilius, Angela M, Klein, Cheri Enders

“…Lopinavir-ritonavir is frequently prescribed to HIV-1-infected women during pregnancy. Decreased lopinavir exposure has been reported during pregnancy, but the…”
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A novel ritonavir paediatric powder formulation is bioequivalent to ritonavir oral solution with a similar food effect by Salem, Ahmed Hamed, Chiu, Yi-Lin, Valdes, Joaquin M, Nilius, Angela M, Klein, Cheri E

“…A novel ritonavir oral powder formulation has been developed to eliminate the alcohol and propylene glycol contents in the current ritonavir oral solution for…”
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In Vitro Antibacterial Potency and Spectrum of ABT-492, a New Fluoroquinolone by Nilius, Angela M, Shen, Linus L, Hensey-Rudloff, Dena, Almer, Laurel S, Beyer, Jill M, Balli, Darlene J, Cai, Yingna, Flamm, Robert K

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Fluoroquinolone Resistance in Streptococcus pneumoniae in United States since 1994-1995 by BRUEGGEMANN, Angela B, COFFMAN, Stacy L, RHOMBERG, Paul, HUYNH, Holly, ALMER, Laurel, NILIUS, Angela, FLAMM, Robert, DOERN, Gary V

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Molecular Characterization of Staphylococcus aureus Isolates from a 2005 Clinical Trial of Uncomplicated Skin and Skin Structure Infections by JONES, Ronald N, NILIUS, Angela M, AKINLADE, Bolanle K, DESHPANDE, Lalitagauri M, NOTARIO, Gerard F

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Cefdinir vs. cephalexin for mild to moderate uncomplicated skin and skin structure infections in adolescents and adults by Giordano, Philip A., Elston, Dirk, Akinlade, Bolanle K., Weber, Kurt, Notario, Gerard F., Busman, Todd A., Cifaldi, Mary, Nilius, Angela M.

“…ABSTRACT Objectives: To compare the efficacy and safety of cefdinir to that of cephalexin in adolescents and adults with mild to moderate uncomplicated skin…”
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Novel Erythromycin Derivatives with Aryl Groups Tethered to the C-6 Position Are Potent Protein Synthesis Inhibitors and Active against Multidrug-Resistant Respiratory Pathogens by Ma, Zhenkun, Clark, Richard F, Brazzale, Antony, Wang, Sanyi, Rupp, Michael J, Li, Leping, Griesgraber, George, Zhang, Suoming, Yong, Hong, Phan, Ly Tam, Nemoto, Peter A, Chu, Daniel T. W, Plattner, Jacob J, Zhang, Xiaolin, Zhong, Ping, Cao, Zhensheng, Nilius, Angela M, Shortridge, Virginia D, Flamm, Robert, Mitten, Michael, Meulbroek, Jon, Ewing, Patty, Alder, Jeff, Or, Yat Sun

“…A novel series of erythromycin derivatives has been discovered with potent activity against key respiratory pathogens, including those resistant to…”
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Design, Synthesis, and Antimicrobial Activity of 6-O-Substituted Ketolides Active against Resistant Respiratory Tract Pathogens by Or, Yat Sun, Clark, Richard F, Wang, Sanyi, Chu, Daniel T. W, Nilius, Angela M, Flamm, Robert K, Mitten, Michael, Ewing, Patty, Alder, Jeff, Ma, Zhenkun

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Ketolides: the future of the macrolides? by Nilius, Angela M, Ma, Zhenkun

“…The prevalence of antibiotic resistance in bacterial pathogens associated with community-acquired respiratory tract infections is increasing. Ketolides,…”
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Examination of noninferiority, safety, and tolerability of lopinavir/ritonavir and raltegravir compared with lopinavir/ritonavir and tenofovir/ emtricitabine in antiretroviral-naïve subjects: the progress study, 48-week results by Reynes, Jacques, Lawal, Adebayo, Pulido, Federico, Soto-Malave, Ruth, Gathe, Joseph, Tian, Min, Fredrick, Linda M, Podsadecki, Thomas J, Nilius, Angela M

“…Current antiretroviral regimens recommended for treatment-naïve patients include 2 nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). The purpose…”
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Have the oxazolidinones lived up to their billing? Future perspectives for this antibacterial class by Nilius, Angela M

“…Linezolid was the first antibacterial oxazolidinone to be approved for clinical use. Oxazolidinones meet a growing medical need to treat multidrug-resistant,…”
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Novel Antibacterial Class:  A Series of Tetracyclic Derivatives by Hinman, Mira M, Rosenberg, Teresa A, Balli, Darlene, Black-Schaefer, Candace, Chovan, Linda E, Kalvin, Douglas, Merta, Philip J, Nilius, Angela M, Pratt, Steve D, Soni, Niru B, Wagenaar, Frank L, Weitzberg, Moshe, Wagner, Rolf, Beutel, Bruce A

“…We describe the synthesis and antibacterial activity of a series of tetracyclic naphthyridones. The members of this series act primarily via inhibition of…”
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Efficacy, tolerability, and parent reported outcomes for cefdinir vs. high-dose amoxicillin/clavulanate oral suspension for acute otitis media in young children by Block, Stan L., Schmier, Jordana K., Notario, Gerard F., Akinlade, Bolanle K., Busman, Todd A., MacKinnon, George E., Halpern, Michael T., Nilius, Angela M.

“…ABSTRACT Objectives: To compare efficacy, tolerability, and parental satisfaction of cefdinir and high-dose amoxicillin/clavulanate oral suspensions given to…”
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Synthesis and Antibacterial Activity of 6-O-Arylbutynyl Ketolides with Improved Activity against Some Key Erythromycin-Resistant Pathogens by Keyes, Robert F, Carter, Justin J, Englund, Erika E, Daly, Melissa M, Stone, Greg G, Nilius, Angela M, Ma, Zhenkun

“…A series of novel 6-O-substituted homopropargyl ketolides was synthesized and evaluated against various erythromycin-resistant pathogens. Promising in vitro…”
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The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class by Sciotti, Richard J., Pliushchev, Marina, Wiedeman, Paul E., Balli, Darlene, Flamm, Robert, Nilius, Angela M., Marsh, Kennan, Stolarik, DeAnne, Jolly, Robert, Ulrich, Roger, Djuric ∗, Stevan W.

“…A novel series of antimicrobials of the oxazolidinone class is disclosed. These compounds are characterized relative to previously described analogues by a…”
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Synthesis and SAR evaluation of oxadiazolopyrazines as selective Haemophilus influenzae antibacterial agents by Beebe, Xenia, Nilius, Angela M., Merta, Philip J., Soni, Niru B., Bui, Mai H., Wagner, Rolf, Beutel, Bruce A.

“…The parallel synthesis and antibacterial activity of 5-hydroxy[1,2,5] oxadiazolo[3,4- b]pyrazines is reported. The compounds were synthesized by condensing…”
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Synthesis and antibacterial activity of 6- O-arylpropargyl-9-oxime-11,12-carbamate ketolides by Beebe, Xenia, Yang, Fan, Bui, Mai H., Mitten, Michael J., Ma, Zhenkun, Nilius, Angela M., Djuric, Stevan W.

“…A series of novel 6- O-arylpropargyl-9-oxime-ketolides was synthesized and evaluated against various pathogens. These new compounds show promising in vitro…”
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Antimicrobial susceptibility and molecular characterization of community-acquired methicillin-resistant Staphylococcus aureus by Almer, Laurel S, Shortridge, Virginia D, Nilius, Angela M, Beyer, Jill M, Soni, Niru B, Bui, Mai H, Stone, Gregory G, Flamm, Robert K

“…Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections are increasing. Since most published data are on nosocomial MRSA, our goal was…”
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Synthesis and Antimicrobial Activity of 4H-4-Oxoquinolizine Derivatives:  Consequences of Structural Modification at the C-8 Position by Ma, Zhenkun, Chu, Daniel T. W, Cooper, Curt S, Li, Qun, Fung, Anthony K. L, Wang, Sanyi, Shen, Linus L, Flamm, Robert K, Nilius, Angela M, Alder, Jeffery D, Meulbroek, Jonathan A, Or, Yat Sun

“…The antibacterial 4H-4-oxoquinolizines were introduced recently to overcome bacterial resistance to fluoroquinolones. They exhibit potent antibacterial…”
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PCR-Oligonucleotide Ligation Assay for Detection of Point Mutations Associated with Quinolone Resistance in Streptococcus pneumoniae by BUI, Mai-Ha, STONE, Gregory G, NILIUS, Angela M, ALMER, Laurel, FLAMM, Robert K

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