Search Results - "Nilaj, Brisilda"

Abstract 431: Malic enzyme 2 inhibition reveals metabolic vulnerability in serine-dependent triple-negative breast cancer by Slayton, Mark D., Farah, Zackariah A., Jeon, Jin Heon, Achreja, Abhinav, Krinkel, Ben, Nilaj, Brisilda, Eu, Yi-Hsien, Sung, Justin, Rosenfeld, Alyssa, Lui, Alisa, Collard, Mason, Bao, Liwei, Cheng, Xu, Kleer, Celina, Loomes, Kerry, Nagrath, Deepak, Merajver, Sofia D.

“…Background & Hypothesis: Treatments for triple-negative breast cancer (TNBC) are limited to chemotherapy, PARP inhibitors and immunotherapies. Tumor metabolism…”
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Abstract 3921: Malic enzyme 2 identified as metabolic target in triple-negative breast cancers with increased serine biosynthesis by Slayton, Mark D., Jeon, Jin Heon, Achreja, Abhinav, Farah, Zackariah A., Nilaj, Brisilda, Eu, Yi-Hsien, Lui, Alisa, Collard, Mason, Bao, Liwei, Kleer, Celina, Nagrath, Deepak, Merajver, Sofia D.

“…Background & Hypothesis: Triple-negative breast cancer (TNBC) is a difficult to treat and deadly form of breast cancer. Pyruvate is an essential intermediate…”
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