Search Results - "Nikonov, Oleg"
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The New Functional Hybrid Chaperone Protein ADGroEL–SacSm
Published in Molecules (Basel, Switzerland) (23-08-2023)“…The creation of new proteins by combining natural domains is a commonly used technique in protein engineering. In this work, we have tested the possibilities…”
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Associations between Neurological Diseases and Mutations in the Human Glycyl-tRNA Synthetase
Published in Biochemistry (Moscow) (2021)“…Aminoacyl-RNA synthetases (aaRSs) are among the key enzymes of protein biosynthesis. They are responsible for conducting the first step in the protein…”
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Recognition of γ-Subunit by β-Subunit in Translation Initiation Factor 2. Stabilization of the GTP-Bound State of I/F 2 in Archaea and Eukaryotes
Published in Biochemistry (Moscow) (01-02-2023)“…Eukaryotic and archaeal translation initiation factor 2 (e/aIF2) functions as a heterotrimeric complex. It consists of three subunits (α, β, γ). α- and…”
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Structure and Function of Archaeal Translation Initiation Factor 2 Fragments Containing Cys2‑Cys2 Motifs
Published in Biochemistry (Moscow) (01-08-2021)“…The heterotrimeric (αβγ) translation initiation factor 2 of archaea and eukaryotes (a/eIF2) supplies the P-site of the ribosome with the initiation tRNA. Its…”
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Multifaceted Mechanism of Amicoumacin A Inhibition of Bacterial Translation
Published in Frontiers in microbiology (12-02-2021)“…Amicoumacin A (Ami) halts bacterial growth by inhibiting the ribosome during translation. The Ami binding site locates in the vicinity of the E-site codon of…”
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Enhanced C/EBP binding to G·T mismatches facilitates fixation of CpG mutations in cancer and adult stem cells
Published in Cell reports (Cambridge) (08-06-2021)“…Somatic mutations in regulatory sites of human stem cells affect cell identity or cause malignant transformation. By mining the human genome for co-occurrence…”
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Enhanced C/EBP binding to G·T mismatches facilitates fixation of CpG mutations in cancer and adult stem cells
Published in Cell reports (Cambridge) (13-07-2021)Get full text
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VPg of Potato Virus Y and Potato Cap-Binding eIF4E Factors: Selective Interaction and Its Supposed Mechanism
Published in Biochemistry (Moscow) (01-09-2021)“…Potato virus Y (PVY) is one of the most common and harmful plant viruses. Translation of viral RNA starts with the interaction between the plant cap-binding…”
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The crucial role of conserved intermolecular H-bonds inaccessible to the solvent in formation and stabilization of the TL5.5 SrRNA complex
Published in The Journal of biological chemistry (22-04-2005)“…Analysis of the structures of two complexes of 5 S rRNA with homologous ribosomal proteins, Escherichia coli L25 and Thermus thermophilus TL5, revealed that…”
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Interaction of Solanum tuberosum L. translation initiation factors eIF4E with potato virus Y VPg: Apprehend and avoid
Published in Biochimie (01-04-2024)“…Potato virus Y (PVY) is one of the most dangerous agricultural pathogens that causes substantial harm to vegetative propagated crops, such as potatoes (Solanum…”
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The influence of laser treatment on the properties of the surface of cylinder-piston group parts
Published in Avtomobilʹnyĭ transport (03-07-2020)Get full text
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The influence of laser treatment on the properties of the surface of cylinder-piston group parts
Published in Avtomobilʹnyj Transport (Harʹkov) (01-06-2020)“…Various valuable materials and technological methods are used to increase the durability of the parts of the cylinder-piston group of internal com-bustion…”
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Structure and Function of Archaeal Translation Initiation Factor 2 Fragments Containing Cys2âCys2 Motifs
Published in Biochemistry (Moscow) (01-08-2021)“…The heterotrimeric ([alpha][beta][gamma]) translation initiation factor 2 of archaea and eukaryotes (a/eIF2) supplies the P-site of the ribosome with the…”
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The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome
Published in Acta crystallographica. Section D, Biological crystallography. (01-04-2019)“…The structure of the γ subunit of archaeal translation initiation factor 2 (aIF2) from Sulfolobus solfataricus (SsoIF2γ) was determined in complex with GDPCP…”
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Recognition of [gamma]-Subunit by [beta]-Subunit in Translation Initiation Factor 2. Stabilization of the GTP-Bound State of I/F 2 in Archaea and Eukaryotes
Published in Biochemistry (Moscow) (01-02-2023)“…Eukaryotic and archaeal translation initiation factor 2 (e/aIF2) functions as a heterotrimeric complex. It consists of three subunits ([alpha], [beta],…”
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Using the Committee Machine Method to Forecasting on the FOREX
Published in 2015 Second International Conference on Mathematics and Computers in Sciences and in Industry (MCSI) (01-08-2015)“…In the paper we consider a particular case of a neural network - a committee method. The described approach was first introduced in the paper by Ablow, C. M…”
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Conference Proceeding -
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Rus İmparatorluğu'nun Basra Körfezi politikasının teşekkülü
Published in Kadim (2021)“…Bu makale Rusya İmparatorluğu’nun Basra Körfezi’ndeki ilk siyasi ve ticari temaslarını ve bölgedeki ilişkilerinin teşekkülünü ele almaktadır. Çalışmada Bağdat…”
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Water clusters in the nucleotide-binding pocket of the protein aIF2γ from the archaeon Sulfolobus solfataricus: Proton transmission
Published in Biochimie (01-02-2016)“…In Archaea and Eukaryotes, the binding of Met-tRNAiMet to the P-site of the ribosome is mediated by translation initiation factor 2 (a/eIF2) which consists of…”
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Crystal structure of the archaeal translation initiation factor 2 in complex with a GTP analogue and Met-tRNAf(Met.)
Published in Journal of molecular biology (25-03-2013)“…Heterotrimeric aIF2αβγ (archaeal homologue of the eukaryotic translation initiation factor 2) in its GTP-bound form delivers Met-tRNAi(Met) to the small…”
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Binding of the 5′-Triphosphate End of mRNA to the γ-Subunit of Translation Initiation Factor 2 of the Crenarchaeon Sulfolobus solfataricus
Published in Journal of molecular biology (25-09-2015)“…The heterotrimeric archaeal IF2 orthologue of eukaryotic translation initiation factor 2 consists of the α-subunit, β-subunit and γ-subunit. Previous studies…”
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