Search Results - "Nikolskaya, E D"
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Design of SAHA-Loaded PLGA Nanoparticles Aimed for Use in Breast Cancer Combination Therapy
Published in Physics of atomic nuclei (01-12-2023)“…This work is devoted to development of a method for synthesis of vorinostat-loaded nanoparticles based on a copolymer of lactic and glycolic acids. The…”
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2
Evaluation of the Synergistic Effect of the Combination of Doxorubicin and Vorinostat on Breast Tumor Cells Using the Loewe Model
Published in Antibiotiki i himioterapiâ (25-12-2023)“…The combination of two or more medications is increasingly more common in the development of new treatment guidelines for common diseases. Thus, the use of…”
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3
Mineralization of Shells of Emulsion Polyelectrolyte Microcapsules by Calcium Carbonate
Published in Crystallography reports (01-12-2023)“…The calcium-carbonate-induced mineralization of multilayer shells of emulsion capsules, formed using layer-by-layer assembly of polyelectrolytes, has been…”
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4
Obtaining and Purifying the Recombinant Domain III of Human Alpha-Fetoprotein
Published in Applied biochemistry and microbiology (01-12-2022)“…Previous studies have demonstrated the applicability of alpha-fetoprotein or its receptor-binding domain fused to the 6-histidine tag at the C-terminus…”
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Cellular internalization of targeted and non-targeted delivery systems for contrast agents based on polyamidoamine dendrimers
Published in Russian chemical bulletin (01-04-2020)“…New high-molecular-weight contrast agents based on polyamidoamine (PAMAM) dendrimers for targeted imaging of malignant tumors characterized by overexpression…”
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6
Polymer particles containing Fe-based metalloporphyrin as a highly efficient stimulator of reactive oxygen species formation in vitro and in vivo
Published in Russian chemical bulletin (01-12-2019)“…Reactive oxygen species are generated by the redox reaction involving metalloporphyrin and ascorbic acid (AA) and lead to oxidative stress followed by cancer…”
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Development of the Composition and Technology for Obtaining Paclitaxel Nanoscale Formulation Consisting of a Conjugate of Polymer Particles with a Protein Vector Molecule
Published in Razrabotka i registraciâ lekarstvennyh sredstv (Online) (25-11-2021)“…Introduction. The use of the anticancer drug paclitaxel is limited due to its high toxicity and lipophilicity. A new polymer composition of paclitaxel has been…”
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Formulation of perspective hepatoprotector polymeric forms based on silybin and ursodeoxycholic acid
Published in Russian chemical bulletin (01-12-2018)“…Silybin (Slb) and ursodeoxycholic acid (UDCA) are hepatoprotectors used in the pathogenetic therapy of liver and biliary tract. However, low bioavailability of…”
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9
Polymer nanoparticles loaded with FeCl-tetraphenylporphyrin for binary catalytic therapy of neoplasms
Published in Russian chemical bulletin (01-02-2018)“…In order to study the possibility of using a metal complex of the porphyrin series, Fe III Cl-tetraphenylporphyrin (FeClTPP), and its polymeric form as…”
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10
Development of a polymer system for the delivery of daunorubicin to tumor cells to overcome drug resistance
Published in Russian chemical bulletin (01-04-2018)“…Method for the synthesis of polymeric nanoparticles (NP) with encapsulated daunorubicin (DNR) was developed on the basis of double emulsion solvent evaporation…”
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11
Physicochemical and Biological Properties of a Nanostructured IR-Photosensitizer Based on Dipropoxybacteriopurpurinimide
Published in Pharmaceutical chemistry journal (01-04-2020)“…The production technology for nanoparticles based on a copolymer of lactic and glycolic acids (PLGA) containing dipropoxybacteriopurpurinimide (DPBPI) and…”
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12
Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids
Published in Russian chemical bulletin (01-10-2017)“…Polymer particles containing carboplatin (CPt) were developed by the inclusion of this antitumor agent in a copolymer of lactic and glycolic acids (PLGA-COOH…”
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13
Polyamidoamine dendrimers with different surface charge as carriers in anticancer drug delivery
Published in Russian journal of bioorganic chemistry (01-03-2017)“…Second-generation (G2) polyamidoamine (PAMAM) dendrimers are branched polymers containing 16 surface primary amine groups. Due to their structural properties,…”
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14
The docetaxel polymeric form and its antitumor activity
Published in Russian journal of bioorganic chemistry (01-05-2017)“…A new pharmaceutical form of the antitumor drug docetaxel (Dtx) has been developed based on a biodegradable copolymer of lactic and glycolic acids (PLGA…”
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15
Preparation of temozolomide-loaded polymer particles and study of their antitumor activity in models of glioma and melanoma
Published in Russian journal of bioorganic chemistry (01-09-2017)“…Temozolomide (TMZ) is a cytostatic drug used in treatment of patients with malignant gliomas and melanomas. The development of innovative formulations for…”
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16
Development of target delivery system based on actinomycin class drugs and recombinant alpha-fetoprotein
Published in Doklady. Biochemistry and biophysics (01-03-2017)“…A recombinant alpha-fetoprotein (rAFP) was obtained in the yeast P. pastoris system, and its functional activity was confirmed. A method for producing polymer…”
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Erratum to: Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids
Published in Russian chemical bulletin (2017)“…To the article “Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids,” by E. D. Nikolskaya, O. A. Zhunina, N. G…”
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18
Evaluation of the Uptake of PLGA-PEG Nanoparticles by Human Cancer Cells
Published in Nanotechnologies in Russia (2018)“…To investigate the patterns of uptake of PLGA-PEG nanoparticles by human cancer cells, FITC-labeled polymer nanoparticles (FPN) are prepared and their…”
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The Combined Effects of Ionizing Radiation and Dendritic Polymers Loaded with Doxorubicin on the MCF-7 Breast Cancer Cell Line
Published in Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a (01-11-2015)“…The dendritic polymers (dendrimers) are perspective nanocontainers for transportation of anticancer drugs into cells and a controlled release of the delivered…”
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Validation of a UV-Spectrophotometric Method for Quantitative Determination of Paclitaxel in a Targeted Delivery System Based on Poly(Lactic–Glycolic Acid) Copolymer Nanoparticles
Published in Pharmaceutical chemistry journal (01-11-2020)“…A UV spectrophotometric method for quantitative determination of paclitaxel in a conjugate of poly(lactic-glycolic acid) (PLGA) copolymer nanoparticles and a…”
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