Search Results - "Nikolakopoulou, Angeliki Maria"

Microglia have a grip on brain microvasculature by Kisler, Kassandra, Nikolakopoulou, Angeliki Maria, Zlokovic, Berislav V.

“…Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published…”
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Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A by Nikolakopoulou, Angeliki Maria, Wang, Yaoming, Ma, Qingyi, Sagare, Abhay P, Montagne, Axel, Huuskonen, Mikko T, Rege, Sanket V, Kisler, Kassandra, Dai, Zhonghua, Körbelin, Jakob, Herz, Joachim, Zhao, Zhen, Zlokovic, Berislav V

“…The low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic and cell signaling transmembrane protein. Endothelial LRP1 clears proteinaceous…”
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Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling by Nikolakopoulou, Angeliki Maria, Zhao, Zhen, Montagne, Axel, Zlokovic, Berislav V

“…Pericytes regulate key neurovascular functions of the brain. Studies in pericyte-deficient transgenic mice with aberrant signaling between endothelial-derived…”
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Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C by Huuskonen, Mikko T, Wang, Yaoming, Nikolakopoulou, Angeliki Maria, Montagne, Axel, Dai, Zhonghua, Lazic, Divna, Sagare, Abhay P, Zhao, Zhen, Fernandez, Jose A, Griffin, John H, Zlokovic, Berislav V

“…Subcortical white matter (WM) stroke accounts for 25% of all strokes and is the second leading cause of dementia. Despite such clinical importance, we still do…”
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3K3A-Activated Protein C Protects the Blood-Brain Barrier and Neurons From Accelerated Ischemic Injury Caused by Pericyte Deficiency in Mice by Wang, Yaoming, Kisler, Kassandra, Nikolakopoulou, Angeliki Maria, Fernandez, Jose A, Griffin, John H, Zlokovic, Berislav V

“…Pericytes, mural cells of brain capillaries, maintain the blood-brain barrier (BBB), regulate cerebral blood flow (CBF), and protect neurons against ischemic…”
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BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo by Hu, Bing, Nikolakopoulou, Angeliki Maria, Cohen-Cory, Susana

“…Brain-derived neurotrophic factor (BDNF) modulates synaptic connectivity by increasing synapse number and by promoting activity-dependent axon arbor growth…”
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Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea by Salehi, Pezhman, Ge, Marshall X, Gundimeda, Usha, Michelle Baum, Leah, Lael Cantu, Homero, Lavinsky, Joel, Tao, Litao, Myint, Anthony, Cruz, Charlene, Wang, Juemei, Nikolakopoulou, Angeliki Maria, Abdala, Carolina, Kelley, Matthew William, Ohyama, Takahiro, Coate, Thomas Matthew, Friedman, Rick A

“…Neuropilin-1 (Nrp1) encodes the transmembrane cellular receptor neuropilin-1, which is associated with cardiovascular and neuronal development and was within…”
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Quantitative 3D reconstruction of viral vector distribution in rodent and ovine brain following local delivery by Poceviciute, Roberta, Mitchell, Kenneth, Nikolakopoulou, Angeliki Maria, Cho, Suehyun K., Ma, Xiaobo, Chen, Phillip, Figueroa, Samantha, Sarmiento, Ethan J., Singh, Aryan, Hartstein, Oren, Loudon, William G., Cros, Florent, Kiselyov, Alexander S.

“…Viral vectors are an active area of research and development to treat diseases of the central nervous system (CNS). However, systemic delivery of…”
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Cell-Autonomous TrkB Signaling in Presynaptic Retinal Ganglion Cells Mediates Axon Arbor Growth and Synapse Maturation during the Establishment of Retinotectal Synaptic Connectivity by Marshak, Sonya, Nikolakopoulou, Angeliki Maria, Dirks, Ron, Martens, Gerard J, Cohen-Cory, Susana

“…BDNF contributes to the activity-dependent establishment and refinement of visual connectivity. In Xenopus, BDNF applications in the optic tectum influence…”
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A "multi-omics" analysis of blood-brain barrier and synaptic dysfunction in APOE4 mice by Barisano, Giuseppe, Kisler, Kassandra, Wilkinson, Brent, Nikolakopoulou, Angeliki Maria, Sagare, Abhay P, Wang, Yaoming, Gilliam, William, Huuskonen, Mikko T, Hung, Shu-Ting, Ichida, Justin K, Gao, Fan, Coba, Marcelo P, Zlokovic, Berislav V

“…Apolipoprotein E4 (APOE4), the main susceptibility gene for Alzheimer's disease, leads to blood-brain barrier (BBB) breakdown in humans and mice. Remarkably,…”
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Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-[beta] signaling by Nikolakopoulou, Angeliki Maria, Zhao, Zhen, Montagne, Axel, Zlokovic, Berislav V

“…Pericytes regulate key neurovascular functions of the brain. Studies in pericyte-deficient transgenic mice with aberrant signaling between endothelial-derived…”
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Synaptic maturation of the Xenopus retinotectal system: Effects of brain-derived neurotrophic factor on synapse ultrastructure by Nikolakopoulou, Angeliki Maria, Meynard, Margarita M., Marshak, Sonya, Cohen-Cory, Susana

“…Synaptogenesis is a dynamic process that involves structural changes in developing axons and dendrites as synapses form and mature. The visual system of…”
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