Search Results - "Nikolaev, V. O."

Compartmentation of cAMP signalling in cardiomyocytes in health and disease by Perera, R. K., Nikolaev, V. O.

“…3′,5′‐cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger critically involved in the regulation of heart function. It has been shown to act…”
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PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways by Vettel, C, Lämmle, S, Ewens, S, Cervirgen, C, Emons, J, Ongherth, A, Dewenter, M, Lindner, D, Westermann, D, Nikolaev, V O, Lutz, S, Zimmermann, W H, El-Armouche, A

“…Recent studies suggest that the signal molecules cAMP and cGMP have antifibrotic effects by negatively regulating pathways associated with fibroblast to…”
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Kinetics of G‐protein‐coupled receptor signals in intact cells by Lohse, M J, Hein, P, Hoffmann, C, Nikolaev, V O, Vilardaga, J‐P, Bünemann, M

“…G‐protein‐coupled receptors (GPCRs) are the largest group of cell surface receptors. They are stimulated by a variety of stimuli and signal to different…”
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Imaging cytoplasmic cAMP in mouse brainstem neurons by Mironov, S L, Skorova, E, Taschenberger, G, Hartelt, N, Nikolaev, V O, Lohse, M J, Kügler, S

“…cAMP is an ubiquitous second messenger mediating various neuronal functions, often as a consequence of increased intracellular Ca2+ levels. While imaging of…”
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Performance of a tubular direct absorption solar collector with a carbon-based nanofluid by Struchalin, P.G., Yunin, V.S., Kutsenko, K.V., Nikolaev, O.V., Vologzhannikova, A.A., Shevelyova, M.P., Gorbacheva, O.S., Balakin, B.V.

“…•we test the performance of a nanofluid-based tubular DASC.•we alter the flow rate, the concentrations of nanoparticles, and the irradiation.•DASC demonstrates…”
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Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6 by Werthmann, R.C., Von Hayn, K., Nikolaev, V.O., Lohse, M.J., Bünemann, M.

“…The crosstalk between Ca 2+ and cAMP signals plays a significant role for the regulation of the endothelial barrier function. The Ca 2+ -elevating agent…”
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Influence of low molecular weight heparins on immune system of surgical patients by Budnyuk, O O, Miastkivska, I V, Vododyuk, R Y, Pustovoyt, P I, Nikolaev, V O

“…Venous thromboembolic complications are potentially dangerous complications to life in patients undergoing surgical intervention. The aim of the work is to…”
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The role of the atrium in the development of the Takotsubo Syndrome – investigation of a patient-specific atrial stem cell model by Brandt, C, Huebscher, D, Syed Ali, G, Maurer, W, Hasenfuss, G, Nikolaev, V O, Streckfuss-Boemeke, K

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From cells to circulating biomarker: BMP10 is a myocyte-secreted peptide with potential to detect atrial fibrillation by E Molina, C, Sommerfeld, L, Zeller, T, Obergassel, J, Wieboldt, H, Conradi, L, Reichenspurner, H, Nikolaev, V O, Kirchhof, P, Fabritz, L

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P2869Role of PDE8 in cAMP dynamics in human atrial fibrillation by Grammatika Pavlidou, N, Pecha, S, Reichenspurner, H, Christ, T, Nikolaev, V O, Molina, C E

“…Abstract Background Cardiac arrhythmias, such as atrial fibrillation (AF), are often related to remodeling of membrane receptors and alterations in…”
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P2863Regional specific remodeling of cGMP pathway in human atrial fibrillation by Bork, N I, Pavlidou, N G, Reiter, B, Reichenspurner, H, Christ, T, Nikolaev, V O, Molina, C E

“…Abstract Background Atrial fibrillation (AF) is accompanied by a profound remodeling of membrane receptors and alterations in cyclic nucleotides-dependent…”
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P933Direct monitoring of cAMP at cardiac ryanodine receptor reveals altered beta2-adrenoceptor dependent regulation in hypertrophy by Berisha, F, Goetz, K R, Wegener, J W, Blankenberg, S, Marks, A R, Lehnart, S E, Nikolaev, V O

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P1851Catecholamine-dependent cAMP signaling in a patient-specific induced pluripotent stem cell takotsubo-model by Streckfuss-Boemeke, K, Huebscher, D, Borchert, T, Nikolaev, V O, Sossalla, S T, Templin, C, Hasenfuss, G

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P5992Why aortic valve disease may persist after surgery? A joint basic science - Clinical effort by Petersen, J, Kloth, B, Grammatika-Pavlidou, N, Eschenhagen, T, Reichenspurner, H, Nikolaev, V O, Christ, T, Molina, C E, Girdauskas, E

“…Abstract Background Diseases of the aortic valve are a common reason for heart surgery. Aortic stenosis (AS) is associated with pressure and aortic…”
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D98 INSIGHTS INTO ENVIRONMENTAL EXPOSURES IN ASTHMA, COPD, AND CONSTRICTIVE BRONCHIOLITIS: Cigarette Smoke Changes Camp Microdomains In Lung Slices by Zuo, H, Han, B, Poppinga, W J, Ringnalda, L, Nikolaev, V O, Schmidt, M

“…In the in vivo model, CAG-Epac1-camps mice were exposed to smoke of filter-free Kentucky 3R4F research cigarettes by whole-body exposure for continuous 4 days…”
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C71 YOU ARE WHAT YOU BREATHE: AIRWAY CELL BIOLOGY IN COPD: Monitoring Local Pulmonary Camp Levels: Combining Precision Cut Lung Slice (pcls) And Fluorescence Resonance Energy Transfer (fret) Technologies In Mice by Zuo, H, Poppinga, W J, Zeisberg, E, Nikolaev, V O, Schmidt, M

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Compartmentation of c AMP signalling in cardiomyocytes in health and disease by Perera, R. K., Nikolaev, V. O.

“…3′,5′‐cyclic adenosine monophosphate (c AMP ) is a ubiquitous second messenger critically involved in the regulation of heart function. It has been shown to…”
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P608ANP potentiates catecholaminergic stress in early cardiac disease by Perera, R K, Steinbrecher, J H, Lehnart, S E, Nikolaev, V O

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Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca 2+ release by Denwood, Geoffrey, Tarasov, Andrei, Salehi, Albert, Vergari, Elisa, Ramracheya, Reshma, Takahashi, Harumi, Nikolaev, Viacheslav O, Seino, Susumo, Gribble, Fiona, Reimann, Frank, Rorsman, Patrik, Zhang, Quan

“…Somatostatin secretion from pancreatic islet δ-cells is stimulated by elevated glucose levels, but the underlying mechanisms have only partially been…”
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cAMP, cGMP and their visualization in living cells using fluorescent microscopy by Nikolaev, V O

“…cAMP and cGMP are ubiquitous second messengers regulating a myriad of intracellular functions. Standard biochemical techniques to measure their levels in cells…”
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