Search Results - "Nikolaev, Eugene N."

Fourier transform ion cyclotron resonance (FT ICR) mass spectrometry: Theory and simulations by Nikolaev, Eugene N., Kostyukevich, Yury I., Vladimirov, Gleb N.

“…Fourier transform ion cyclotron resonance (FT ICR) mass spectrometer offers highest resolving power and mass accuracy among all types of mass spectrometers…”
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Spherical Sampler Probes Enhance the Robustness of Ambient Ionization Mass Spectrometry for Rapid Drugs Screening by Shamraeva, Mariya A, Bormotov, Denis S, Shamarina, Ekaterina V, Bocharov, Konstantin V, Peregudova, Olga V, Pekov, Stanislav I, Nikolaev, Eugene N, Popov, Igor A

“…Ambient ionization mass spectrometry has become one of the most promising approaches for rapid and high-throughput screening of small molecules in complex…”
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Determination of Brain Tissue Samples Storage Conditions for Reproducible Intraoperative Lipid Profiling by Pekov, Stanislav I, Zhvansky, Evgeny S, Eliferov, Vasily A, Sorokin, Anatoly A, Ivanov, Daniil G, Nikolaev, Eugene N, Popov, Igor A

“…Ex-vivo molecular profiling has recently emerged as a promising method for intraoperative tissue identification, especially in neurosurgery. The short-term…”
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Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling by Pekov, Stanislav I., Eliferov, Vasily A., Sorokin, Anatoly A., Shurkhay, Vsevolod A., Zhvansky, Evgeny S., Vorobyev, Alexander S., Potapov, Alexander A., Nikolaev, Eugene N., Popov, Igor A.

“…The development of perspective diagnostic techniques in medicine requires efficient high-throughput biological sample analysis methods. Here, we present an…”
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Synthesis of model humic substances: a mechanistic study using controllable H/D exchange and Fourier transform ion cyclotron resonance mass spectrometry by Zherebker, Alexander Ya, Airapetyan, David, Konstantinov, Andrey I, Kostyukevich, Yury I, Kononikhin, Alexey S, Popov, Igor A, Zaitsev, Kirill V, Nikolaev, Eugene N, Perminova, Irina V

“…The products of the oxidative coupling of phenols are frequently used as synthetic analogues to natural humic substances (HS) for biomedical research. However,…”
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Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo by Ilyushin, Denis G., Smirnov, Ivan V., Belogurov, Alexey A., Dyachenko, Igor A., Zharmukhamedova, Tatiana lu, Novozhilova, Tatjana I., Bychikhin, Eugene A., Serebryakova, Marina V., Kharybin, Oleg N., Murashev, Arkadii N., Anikienko, Konstantin A., Nikolaev, Eugene N., Ponomarenko, Natalia A., Genkin, Dmitry D., Blackburn, G. Michael, Masson, Patrick, Gabibov, Alexander G.

“…The creation of effective bioscavengers as a pretreatment for exposure to nerve agents is a challenging medical objective. We report a recombinant method using…”
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Fourier Transform Ion Cyclotron Resonance Mass Resolution and Dynamic Range Limits Calculated by Computer Modeling of Ion Cloud Motion by Vladimirov, Gleb, Hendrickson, Christopher L., Blakney, Greg T., Marshall, Alan G., Heeren, Ron M. A., Nikolaev, Eugene N.

“…Particle-in-Cell (PIC) ion trajectory calculations provide the most realistic simulation of Fourier transform ion cyclotron resonance (FT-ICR) experiments by…”
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The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins by Kashirina, Daria N, Percy, Andrew J, Pastushkova, Liudmila Kh, Borchers, Christoph H, Kireev, Kirill S, Ivanisenko, Vladimir A, Kononikhin, Alexey S, Nikolaev, Eugene N, Larina, Irina M

“…The conditions of space flight have a significant effect on the physiological processes in the human body, yet the molecular mechanisms driving physiological…”
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Shapley Value as a Quality Control for Mass Spectra of Human Glioblastoma Tissues by Zavorotnyuk, Denis S., Sorokin, Anatoly A., Pekov, Stanislav I., Bormotov, Denis S., Eliferov, Vasiliy A., Bocharov, Konstantin V., Nikolaev, Eugene N., Popov, Igor A.

“…The automatic processing of high-dimensional mass spectrometry data is required for the clinical implementation of ambient ionization molecular profiling…”
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Mass spectrometric characterization of photooxidative protein modifications in Arabidopsis thaliana thylakoid membranes by Galetskiy, Dmitry, Lohscheider, Jens N., Kononikhin, Alexey S., Popov, Igor A., Nikolaev, Eugene N., Adamska, Iwona

“…Oxidative and nitrosative stress leaves footprints in the plant chloroplast in the form of oxidatively modified proteins. Using a mass spectrometric approach,…”
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Phosphorylation and nitration levels of photosynthetic proteins are conversely regulated by light stress by Galetskiy, Dmitry, Lohscheider, Jens N., Kononikhin, Alexey S., Popov, Igor A., Nikolaev, Eugene N., Adamska, Iwona

“…Using a label-free mass spectrometric approach, we investigated light-induced changes in the distribution of phosphorylated and nitrated proteins within…”
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Lipid Profiles of Human Brain Tumors Obtained by High-Resolution Negative Mode Ambient Mass Spectrometry by Zavorotnyuk, Denis S., Pekov, Stanislav I., Sorokin, Anatoly A., Bormotov, Denis S., Levin, Nikita, Zhvansky, Evgeny, Semenov, Savva, Strelnikova, Polina, Bocharov, Konstantin V., Vorobiev, Alexander, Kononikhin, Alexey, Shurkhay, Vsevolod, Nikolaev, Eugene N., Popov, Igor A.

“…Alterations in cell metabolism, including changes in lipid composition occurring during malignancy, are well characterized for various tumor types. However, a…”
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Copper(II)-Assisted Enantiomeric Analysis of d,l-Amino Acids Using the Kinetic Method:  Chiral Recognition and Quantification in the Gas Phase by Tao, W. A, Zhang, Duxi, Nikolaev, Eugene N, Cooks, R. Graham

“…Chiral recognition of d- and l-amino acids is achieved and mixtures of enantiomers quantified in the gas phase, using the kinetics of competitive unimolecular…”
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Realistic modeling of ion cloud motion in a Fourier transform ion cyclotron resonance cell by use of a particle-in-cell approach by Nikolaev, Eugene N., Heeren, Ron M. A., Popov, Alexander M., Pozdneev, Alexander V., Chingin, Konstantin S.

“…Using a ‘Particle‐In‐Cell’ approach taken from plasma physics we have developed a new three‐dimensional (3D) parallel computer code that today yields the…”
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Simple Synthesis of Ruthenium π Complexes of Aromatic Amino Acids and Small Peptides by Perekalin, Dmitry S., Karslyan, Eduard E., Petrovskii, Pavel V., Nelyubina, Yulia V., Lyssenko, Konstantin A., Kononikhin, Alexey S., Nikolaev, Eugene N., Kudinov, Alexander R.

“…The interaction of [Ru(η6‐C10H8)(Cp)]+ (Cp=C5H5) with aromatic amino acids (L‐phenylalanine, L‐tyrosine, L‐tryptophane, D‐phenylglycine, and…”
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Initial Experimental Characterization of a New Ultra-High Resolution FTICR Cell with Dynamic Harmonization by Nikolaev, Eugene N., Boldin, Ivan A., Jertz, Roland, Baykut, Gökhan

“…A new Fourier transform ion cyclotron resonance (FTICR) cell based on completely new principles of formation of the effective electric potential distribution…”
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Fourier transform ion cyclotron resonance cell with dynamic harmonization of the electric field in the whole volume by shaping of the excitation and detection electrode assembly by Boldin, Ivan A., Nikolaev, Eugene N.

“…A new principle of formation of the effective electric field distribution in a Penning trap is presented. It is based on the concept of electric potential…”
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Fine Structure in Isotopic Peak Distributions Measured Using a Dynamically Harmonized Fourier Transform Ion Cyclotron Resonance Cell at 7 T by Nikolaev, Eugene N, Jertz, Roland, Grigoryev, Anton, Baykut, Gökhan

“…The fine structure of isotopic peak clusters in mass spectra of reserpine and substance P are measured using Fourier transform ion cyclotron resonance mass…”
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Dissection of the deep-blue autofluorescence changes accompanying amyloid fibrillation by Tikhonova, Tatiana N., Rovnyagina, Nataliya R., Zherebker, Alexander Ya, Sluchanko, Nikolai N., Rubekina, Anna A., Orekhov, Anton S., Nikolaev, Eugene N., Fadeev, Victor V., Uversky, Vladimir N., Shirshin, Evgeny A.

“…Pathogenesis of numerous diseases is associated with the formation of amyloid fibrils. Extrinsic fluorescent dyes, including Thioflavin T (ThT), are used to…”
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Normalization methods for reducing interbatch effect without quality control samples in liquid chromatography-mass spectrometry-based studies by Tokareva, Alisa O., Chagovets, Vitaliy V., Kononikhin, Alexey S., Starodubtseva, Natalia L., Nikolaev, Eugene N., Frankevich, Vladimir E.

“…Data normalization is an essential part of a large-scale untargeted mass spectrometry metabolomics analysis. Autoscaling, Pareto scaling, range scaling, and…”
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