Search Results - "Niklas, Norbert"

Machine learning-based prediction of fainting during blood donations using donor properties and weather data as features by Suessner, Susanne, Niklas, Norbert, Bodenhofer, Ulrich, Meier, Jens

“…Abstract Background and objectives Fainting is a well-known side effect of blood donation. Such adverse experiences can diminish the return rate for further…”
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Rapid, scalable and highly automated HLA genotyping using next-generation sequencing: a transition from research to diagnostics by Danzer, Martin, Niklas, Norbert, Stabentheiner, Stephanie, Hofer, Katja, Pröll, Johannes, Stückler, Christina, Raml, Edeltraud, Polin, Helene, Gabriel, Christian

“…Human leukocyte antigen matching at allelic resolution is proven clinically significant in hematopoietic stem cell transplantation, lowering the risk of…”
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A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas by Wimmer, Monika, Zauner, Roland, Ablinger, Michael, Piñón-Hofbauer, Josefina, Guttmann-Gruber, Christina, Reisenberger, Manuela, Lettner, Thomas, Niklas, Norbert, Proell, Johannes, Sajinovic, Mila, De Souza, Paul, Hainzl, Stefan, Kocher, Thomas, Murauer, Eva M, Bauer, Johann W, Strunk, Dirk, Reichelt, Julia, Mellick, Albert Sleiman, Wally, Verena

“…Cutaneous squamous cell carcinomas (cSCC) are the primary cause of premature deaths in patients suffering from the rare skin-fragility disorder recessive…”
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Introduction of the hybcell-based compact sequencing technology and comparison to state-of-the-art methodologies for KRAS mutation detection by Zopf, Agnes, Raim, Roman, Danzer, Martin, Niklas, Norbert, Spilka, Rita, Pröll, Johannes, Gabriel, Christian, Nechansky, Andreas, Roucka, Markus

“…The detection of KRAS mutations in codons 12 and 13 is critical for anti-EGFR therapy strategies; however, only those methodologies with high sensitivity,…”
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Mutation Analysis of Nine Chordoma Specimens by Targeted Next-Generation Cancer Panel Sequencing by Fischer, Carina, Scheipl, Susanne, Zopf, Agnes, Niklas, Norbert, Deutsch, Alexander, Jorgensen, Mette, Lohberger, Birgit, Froehlich, Elke Verena, Leithner, Andreas, Gabriel, Christian, Liegl-Atzwanger, Bernadette, Rinner, Beate

“…Chordoma is a rare primary malignant bone tumour. Treatment options are mainly restricted to surgical excision, since chordomas are largely resistant to…”
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Sequence Capture and Next Generation Resequencing of the MHC Region Highlights Potential Transplantation Determinants in HLA Identical Haematopoietic Stem Cell Transplantation by JOHANNES, Pröll, MARTIN, Danzer, OTTO, Krieger, CHRISTIAN, Gabriel, STEPHANIE, Stabentheiner, NORBERT, Niklas, CHRISTA, Hackl, KATJA, Hofer, SABINE, Atzmüller, PETER, Hufnagl, CHRISTIAN, Gülly, HANNS, Hauser

“…How cells coordinate the immune system activities is important for potentially life-saving organ or stem cell transplantations. Polymorphic immunoregulatory…”
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The Impact of Digital Transformation on Blood Donation and Donor Characteristics by Niklas, Norbert, Loimayr, Claudia, Lenz, Julia, Süßner, Susanne, Schuster, Gerhard, Jungwirth, David, Watzinger, Werner, Federsel, Stephan

“…Abstract Introduction: The management of an adequate donor pool is a constant and challenging task for blood centers in order to provide blood supply. New…”
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High-Throughput Sequencing of the Major Histocompatibility Complex following Targeted Sequence Capture by Pröll, Johannes, Fischer, Carina, Michelitsch, Gabriele, Danzer, Martin, Niklas, Norbert

“…The Human Major Histocompatibility Complex (MHC) is a highly polymorphic region full of immunoregulatory genes. The MHC codes for the human leukocyte antigens…”
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Routine performance and errors of 454 HLA exon sequencing in diagnostics by Niklas, Norbert, Pröll, Johannes, Danzer, Martin, Stabentheiner, Stephanie, Hofer, Katja, Gabriel, Christian

“…Next-generation sequencing (NGS) has changed genomics significantly. More and more applications strive for sequencing with different platforms. Now, in 2012,…”
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Biomarker Discovery in Rare Malignancies: Development of a miRNA Signature for RDEB-cSCC by Zauner, Roland, Wimmer, Monika, Atzmueller, Sabine, Proell, Johannes, Niklas, Norbert, Ablinger, Michael, Reisenberger, Manuela, Lettner, Thomas, Illmer, Julia, Dorfer, Sonja, Koller, Ulrich, Guttmann-Gruber, Christina, Hofbauer, Josefina Piñón, Bauer, Johann W, Wally, Verena

“…Machine learning has been proven to be a powerful tool in the identification of diagnostic tumor biomarkers but is often impeded in rare cancers due to small…”
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Qualifying high-throughput immune repertoire sequencing by Niklas, Norbert, Pröll, Johannes, Weinberger, Johannes, Zopf, Agnes, Wiesinger, Karin, Krismer, Konstantin, Bettelheim, Peter, Gabriel, Christian

“…•1,433,471 individual IGHV (B cell) and TCRβ (T cell) VDJ sequences of five healthy control and five CLL samples were compared.•Analysis strategy for diversity…”
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Human immunodeficiency virus type 1 drug resistance testing: Evaluation of a new ultra-deep sequencing-based protocol and comparison with the TRUGENE HIV-1 Genotyping Kit by Stelzl, Evelyn, Pröll, Johannes, Bizon, Beata, Niklas, Norbert, Danzer, Martin, Hackl, Christa, Stabentheiner, Stephanie, Gabriel, Christian, Kessler, Harald H.

“…► Ultra-deep sequencing may be a good alternative to Sanger sequencing in future. ► It shows good results for HIV-1 drug resistance testing. ► For use in the…”
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cFinder: definition and quantification of multiple haplotypes in a mixed sample by Niklas, Norbert, Hafenscher, Julia, Barna, Agnes, Wiesinger, Karin, Pröll, Johannes, Dreiseitl, Stephan, Preuner-Stix, Sandra, Valent, Peter, Lion, Thomas, Gabriel, Christian

“…Next-generation sequencing allows for determining the genetic composition of a mixed sample. For instance, when performing resistance testing for BCR-ABL1 it…”
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