Search Results - "Nikitas, John"

Phase 2 trial of PSMA PET CT versus planar bone scan and CT in prostate cancer patients progressing while on androgen deprivation therapy by Nikitas, John, Gafita, Andrei, Benz, Matthias R., Djaïleb, Loïc, Farolfi, Andrea, Hotta, Masatoshi, Sonni, Ida, Alano, Rejah, Rettig, Matthew, Shen, John, Armstrong, Wesley, Grogan, Tristan, Liu, Sandy, Czernin, Johannes, Calais, Jeremie

“…For prostate cancer patients who experience biochemical progression during androgen deprivation therapy (ADT), prostate-specific membrane antigen positron…”
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New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine by Moen, Erika L., Mariani, Christopher J., Zullow, Hayley, Jeff-Eke, Meselle, Litwin, Edward, Nikitas, John N., Godley, Lucy A.

“…Summary 5‐methylcytosine (5‐mC) and 5‐hydroxymethylcytosine (5‐hmC) play a critical role in development and normal physiology. Alterations in 5‐mC and 5‐hmC…”
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Pathophysiology and Management of Chest Wall Pain after Surgical and Non-Surgical Local Therapies for Lung Cancer by Nikitas, John, Yanagawa, Jane, Sacks, Sandra, Hui, Edward K., Lee, Alan, Deng, Jie, Abtin, Fereidoun, Suh, Robert, Lee, Jay M., Toste, Paul, Burt, Bryan M., Revels, Sha’Shonda L., Cameron, Robert B., Moghanaki, Drew

“…Chest wall pain syndromes can emerge following local therapies for lung cancer and can adversely affect patients’ quality-of-life. This can occur after lung…”
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Treatment of oligometastatic lung cancer with brain metastases using stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) by Nikitas, John, Roach, Michael, Robinson, Cliff, Bradley, Jeffrey, Huang, Jiayi, Perkins, Stephanie, Tsien, Christina, Abraham, Christopher

“…•Stereotactic radiation was used for both lung cancer primaries and brain metastases.•Oligometastatic and stage I patients achieved similar survival and local…”
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Treatment of T3N0 non-small cell lung cancer with chest wall invasion using stereotactic body radiotherapy by Kennedy, William R., Gabani, Prashant, Nikitas, John, Samson, Pamela P., Robinson, Clifford G., Bradley, Jeffrey D., Roach, Michael C.

“…•The role of SBRT for T3N0 lung cancer invading the chest wall is unknown.•We treated 12 patients with T3N0 chest wall-invading lung cancer with SBRT.•Local…”
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PD15-08 PROSTATE BED DEFORMATIONS AND DOSIMETRIC IMPLICATIONS: AN EXPLORATORY ANALYSIS OF A PHASE II CLINICAL TRIAL (SCIMITAR) by Jiang, Tommy, Smith, Lauren, Valle, Luca, Ballas, Leslie, Nikitas, John, Steinberg, Michael, Reiter, Robert, Cao, Minsong, Kishan, Amar

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Prostate-specific membrane antigen PET/CT-guided, metastasis-directed radiotherapy for oligometastatic castration-resistant prostate cancer by Nikitas, John, Castellanos, Angela, Farolfi, Andrea, Seyedroudbari, Ameen, Kishan, Amar Upadhyaya, Nickols, Nicholas George, Steinberg, Michael L., Czernin, Johannes, Calais, Jeremie

“…e17057 Background: Systemic treatments for metastatic castration-resistant prostate cancer (mCRPC) include androgen deprivation therapy (ADT), androgen…”
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Repeat stereotactic body radiation therapy (SBRT) for salvage of isolated local recurrence after definitive lung SBRT by Kennedy, William R, Gabani, Prashant, Nikitas, John, Robinson, Clifford G, Bradley, Jeffrey D, Roach, Michael C

“…Highlights•Local recurrences occur in 10–15% of early stage NSCLC after definitive SBRT. •Salvage SBRT safety and efficacy for local recurrence after initial…”
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Update from the PSMA-dRT trial: A randomized phase III trial of PSMA-PET prior to definitive radiation therapy for unfavorable intermediate-risk or high-risk prostate cancer by Nikitas, John, Lam, Ethan C., Booker, Kiara M, Fendler, Wolfgang P., Eiber, Matthias, Hadaschik, Boris A., Herrmann, Ken, Hirmas, Nader, Lanzafame, Helena, Stuschke, Martin, Czernin, Johannes, Steinberg, Michael L., Nickols, Nicholas George, Kishan, Amar Upadhyaya, Calais, Jeremie

“…291 Background: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) has superior diagnostic accuracy for…”
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Systemic and tumor-directed therapy for oligorecurrent metastatic prostate cancer (SATURN): Primary endpoint results of a phase II clinical trial by Nikitas, John, Rettig, Matthew, Shen, John, Reiter, Robert Evan, Lee, Alan, Steinberg, Michael L., Valle, Luca Faustino, Sachdeva, Ankush, Romero, Tahmineh, Calais, Jeremie, Czernin, Johannes, Nickols, Nicholas George, Kishan, Amar Upadhyaya

“…174 Background: Nearly all men with metastatic hormone-sensitive prostate cancer who receive intermittent androgen deprivation therapy (ADT) will experience a…”
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Treatment intensification strategies for men undergoing definitive radiotherapy for high-risk prostate cancer by Nikitas, John, Kishan, Amar, Chang, Albert, Duriseti, Sai, Nichols, Nicholas G., Reiter, Robert, Rettig, Matthew, Brisbane, Wayne, Steinberg, Michael L., Valle, Luca

“…Purpose Treatment intensification of external beam radiotherapy (EBRT) plays a crucial role in the treatment of high-risk prostate cancer. Methods We performed…”
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Stereotactic Body Radiotherapy for Early-Stage Multiple Primary Lung Cancers by Nikitas, John, DeWees, Todd, Rehman, Sana, Abraham, Chris, Bradley, Jeff, Robinson, Cliff, Roach, Michael

“…Patients with multiple primary lung cancers increasingly receive multiple courses of stereotactic body radiotherapy (SBRT). We aimed to clarify the efficacy…”
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Systemic and Tumor-directed Therapy for Oligorecurrent Metastatic Prostate Cancer (SATURN): Primary Endpoint Results from a Phase 2 Clinical Trial by Nikitas, John, Rettig, Matthew, Shen, John, Reiter, Robert, Lee, Alan, Steinberg, Michael L., Valle, Luca F., Sachdeva, Ankush, Romero, Tahmineh, Calais, Jeremie, Czernin, Johannes, Nickols, Nicholas G., Kishan, Amar U.

“…In men with prostate-specific membrane antigen–defined, oligorecurrent M1a–b prostate cancer, short-course androgen annihilation therapy and…”
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Prostate-Specific Membrane Antigen PET/CT-Guided, Metastasis-Directed Radiotherapy for Oligometastatic Castration-Resistant Prostate Cancer by Nikitas, John, Castellanos Rieger, Angela, Farolfi, Andrea, Seyedroudbari, Ameen, Kishan, Amar U, Nickols, Nicholas G, Steinberg, Michael L, Valle, Luca F, Rettig, Matthew, Czernin, Johannes, Calais, Jeremie

“…Systemic treatments for metastatic castration-resistant prostate cancer (mCRPC) include androgen deprivation therapy, androgen receptor pathway inhibitors,…”
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Long-Term Quality-of-Life Outcomes After Prostate Radiation Therapy With or Without High-Dose-Rate Brachytherapy Boost: Post Hoc Analysis of TROG 03.04 RADAR by Ong, Wee Loon, Nikitas, John, Joseph, David, Steigler, Allison, Millar, Jeremy, Valle, Luca, Steinberg, Michael L., Ma, Ting Martin, Reiter, Robert E., Rettig, Matthew B., Nickols, Nicholas G., Chang, Albert, Zaorsky, Nicholas G., Spratt, Daniel E., Romero, Tahmineh, Kishan, Amar U.

“…Adding high-dose-rate brachytherapy (BT) boost to external beam radiation therapy (EBRT) improves biochemical control but may affect patient-reported quality…”
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Randomized Trial of Prostate-Specific Membrane Antigen PET/CT Before Definitive Radiotherapy for Unfavorable Intermediate- and High-Risk Prostate Cancer (PSMA-dRT Trial) by Nikitas, John, Lam, Ethan, Booker, Kiara Adame, Fendler, Wolfgang P, Eiber, Matthias, Hadaschik, Boris, Herrmann, Ken, Hirmas, Nader, Lanzafame, Helena, Stuschke, Martin, Czernin, Johannes, Steinberg, Michael L, Nickols, Nicholas G, Kishan, Amar U, Calais, Jeremie

“…This multicenter randomized phase III trial (NCT04457245) evaluated the effect of performing prostate-specific membrane antigen (PSMA) PET/CT before definitive…”
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The role of adaptive planning in margin-reduced, MRI-guided stereotactic body radiotherapy to the prostate bed following radical prostatectomy: Post-hoc analysis of a phase II clinical trial by Nikitas, John, Smith, Lauren M., Gao, Yu, Ma, Ting Martin, Sachdeva, Ankush, Yoon, Stephanie M., Jiang, Tommy, Low, Daniel A., Ballas, Leslie K., Steinberg, Michael L., Cao, Minsong, Kishan, Amar U.

“…•CTV and PTV volume and shape were well-preserved. A 3 mm isotropic PTV margin allowed for adequate CTV coverage in more than 90% of patients.•There were…”
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Stereotactic intensity modulated radiotherapy after radical prostatectomy (SCIMITAR): Two-year quality of life and toxicity outcomes of a multicenter phase II trial by Nikitas, John, Ballas, Leslie K., Franco, Antonio, Lynch, Connor, Ma, Ting Martin, Valle, Luca Faustino, Romero, Tahmineh, Sachdeva, Ankush, Chong, Natalie, Basehart, Vincent, Reiter, Robert Evan, Saigal, Christopher, Chamie, Karim, Litwin, Mark S., Rettig, Matthew, Nickols, Nicholas George, Steinberg, Michael L., Cao, Minsong, Liauw, Stanley L., Kishan, Amar Upadhyaya

“…317 Background: Postoperative radiotherapy for men with biochemical recurrence or adverse pathologic features after radical prostatectomy (RP) remains…”
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Prostate-Specific Antigen Response to Androgen Deprivation Therapy in the Neoadjuvant Setting for High-Risk Prostate Adenocarcinoma (PIRANHA): Pooled Analysis of Two Randomized Clinical Trials by Nikitas, John, Ong, Wee Loon, Carrier, Nathalie, Romero, Tahmineh, Millar, Jeremy, Steinberg, Michael L., Rettig, Matthew B., Boutros, Paul C., Reiter, Robert, Nickols, Nicholas G., Valle, Luca, McGuire, Sean E., Spratt, Daniel E., Souhami, Luis, Roy, Soumyajit, Martin, Jarad M., Joseph, David, Nabid, Abdenour, Kishan, Amar U.

“…A suboptimal prostate-specific antigen (PSA) response to neoadjuvant androgen deprivation therapy (ADT) among men who go on to receive definitive radiation…”
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DNMT3A regulates T-cell development and suppresses T-all transformation by Challen, Grant, Kothari, Alok, Nikitas, John, Celik, Hamza, Kramer, Ashley

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