Search Results - "Nikisch, G"

Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: A pilot study by Nikisch, Georg, Eap, Chin B., Baumann, Pierre

“…The antidepressant activity of citalopram (R,S-CIT) is mainly due to its (S)-enantiomer (S-CIT). P-glycoprotein (P-gp), encoded by the ABCB1 gene, is a…”
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Three-year follow-up of a patient with early-onset Alzheimer's disease with presenilin-2 N141I mutation - case report and review of the literature by Nikisch, G, Hertel, A, Kiessling, B, Wagner, Th, Krasz, D, Hofmann, E, Wiedemann, G

“…Autosomal dominant early-onset Alzheimer disease (EOAD) is a heterogeneous condition that has been associated with mutations in 3 different genes: the amyloid…”
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Familial Alzheimer's disease with presenilin 2 N141I mutation. A case report by Nikisch, G, Wiedemann, G, Kiessling, B, Hertel, A

“…Alzheimer's disease (AD) is the most common form of dementia. Approximately 0.5 per cent of all AD is caused by single major gene mutations and autosomal…”
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Involvement and role of antidepressant drugs of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor function by Nikisch, Georg

“…Changes in the hypothalamic-pituitary-adrenal (HPA) axis are characteristic of major depression. Because the effects of glucocorticoids are mediated by…”
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Quetiapine affects neuropeptide Y and corticotropin-releasing hormone in cerebrospinal fluid from schizophrenia patients: relationship to depression and anxiety symptoms and to treatment response by Nikisch, Georg, Baumann, Pierre, Liu, Tianmin, Mathé, Aleksander A.

“…Cumulative evidence indicates that neuropeptides play a role in the pathophysiology of schizophrenia. Early data showed increased neuropeptide Y (NPY) in…”
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CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy by Nikisch, Georg, Mathé, Aleksander A

“…Abstract Antidepressant drugs affect monoamines and neuropeptides in human cerebrospinal fluid (CSF) and in rodent brain. The purpose of this study was to…”
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Cytochrome P450 and ABCB1 genetics: association with quetiapine and norquetiapine plasma and cerebrospinal fluid concentrations and with clinical response in patients suffering from schizophrenia. A pilot study by Nikisch, Georg, Baumann, Pierre, Oneda, Beatrice, Kiessling, Bernhard, Weisser, Heike, Mathé, Aleksander A, Yoshitake, Takashi, Kehr, Jan, Wiedemann, Georg, Eap, Chin B

“…Variability in response to atypical antipsychotic drugs is due to genetic and environmental factors. Cytochrome P450 (CYP) isoforms are implicated in the…”
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Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression : relationship with s-citalopram concentrations in plasma and cerebrospinal fluid (CSF) and clinical response by NIKISCH, Georg, MATHE, Aleksander A, CZERNIK, Adelheid, THIELE, Jutta, BOHNER, Jürgen, EAP, Chin B, AGREN, Hans, BAUMANN, Pierre

“…A dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is a well-documented neurobiological finding in major depression. Moreover, clinically…”
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Quetiapine and Norquetiapine in Plasma and Cerebrospinal Fluid of Schizophrenic Patients Treated With Quetiapine: Correlations to Clinical Outcome and HVA, 5-HIAA, and MHPG in CSF by NIKISCH, Georg, BAUMANN, Pierre, WIEDEMANN, Georg, KIESSLING, Bernhard, WEISSER, Heike, HERTEL, Andreas, YOSHITAKE, Takashi, KEHR, Jan, MATHE, Aleksander A

“…This study investigated concentrations of quetiapine and norquetiapine in plasma and cerebrospinal fluid (CSF) in 22 schizophrenic patients after 4-week…”
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Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram by Nikisch, Georg, Ågren, Hans, Eap, Chin B., Czernik, Adelheid, Baumann, Pierre, Mathé, Aleksander A.

“…Neuropeptides appear to play a role in the pathophysiology of depression and electroconvulsive treatment and lithium affect these compounds in human…”
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Retraction notice to “Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine” [J Psychiat Res 44 (2010) 754–759] by Nikisch, Georg, Baumann, Pierre, Kießling, Bernhard, Reinert, Michael, Wiedemann, Georg, Kehr, Jan, Mathé, Aleksander A, Piel, Markus, Roesch, Frank, Weisser, Heike, Schneider, Peter, Hertel, Andreas

“…This article has been retracted at the request of the Editors: please see Elsevier Policy on Article Withdrawal…”
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Relationship between dopamine D 2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine (Retraction of vol 44, pg 754, 2010) by Nikisch, G, Baumann, P, Kiessling, B, Reinert, M, Wiedemann, G, Kehr, J, Mathe, AA, Piel, M, Roesch, F, Weisser, H

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Antidepressant and anxiolytic effects of quetiapine strongly correlate to neuropeptide Y increase and corticotropin-releasing hormone decrease in CSF from schizophrenic patients by Mathe, A, Nikisch, G, Liu, T, Baumann, P

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Search for biological correlates of depression and mechanisms of action of antidepressant treatment modalities. Do neuropeptides play a role? by Mathé, Aleksander A, Husum, Henriette, Khoury, Aram El, Jiménez-Vasquez, Patricia, Gruber, Susanne H.M, Wörtwein, Gitta, Nikisch, Georg, Baumann, Pierre, Ågren, Hans, Andersson, Weronica, Södergren, Åsa, Angelucci, Francesco

“…Abstract Dysregulation of the monoaminergic systems is likely a sufficient but not a necessary cause of depression. A wealth of data indicates that…”
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Stereoselective metabolism of citalopram in plasma and cerebrospinal fluid of depressive patients -: Relationship with S-HIAA in CSF and clinical response by Nikisch, G, Mathé, AA, Czernik, A, Eap, CB, Jiménez-Vasquez, P, Brawand-Amey, M, Baumann, P

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Stereoselective metabolism of citalopram in Plasma and cerebrospinal fluid of depressive patients: Relationship with 5-HIAA in CSF and clinical response by NIKISCH, Georg, MATHE, Aleksander A, CZERNIK, Adelheid, EAP, Chin B, JIMENEZ-VASQUEZ, Patricia, BRAWAND-AMEY, Marlyse, BAUMANN, Pierre

“…Plasma and cerebrospinal fluid (CSF) concentrations of the enantiomers of citalopram (CIT), its N-demethylated metabolite demethylcitalopram (DCIT) and its…”
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P.2.b.013 Neuropeptides in human cerebrospinal fluid and in brains of animal models of depression - effects of treatment by Mathé, A.A., Nikisch, G., Agren, H., Baumann, P., El Khoury, A., Gruber, S.H.M., Husum, H., Jiménez-Vasquez, P., Wortwein, G., Andersson, W., Aitchison, K.J., McGuffin, P.

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Neuroendocrine, biochemical and pharmacokinetic effects of a long-term treatment with the selective serotonin reuptake inhibitor (SSRI) citalopram in major depressive disorder by Nikisch, G., Czernik, A., Mathé, A.A., Diegmann, J., Amey, M., Baumann, P.

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Neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH) in human CSF and in brain of animal models of depression by Mathe, AA, Agren, H, Andersson, W, Baumann, P, El Khoury, A, Gruber, SHM, Husum, H, Jimenez-Vasquez, P, Nikisch, G, Wortwein, G

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Self concept and parental images in patients with affective disorders--a clinical study with the Giessen Test by Böker, H, Budischewski, K, Walesch, K, Nikisch, G

“…The relationship between self, ideal self and normative self was studied in a sample of 139 patients with affective disorders and 73 patients with orthopaedic…”
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