Search Results - "Nikiforov, Yuri"

ROLE OF MOLECULAR MARKERS IN THYROID NODULE MANAGEMENT: THEN AND NOW by Nikiforov, Yuri E

“…To describe the evolution and clinical utility of molecular testing for thyroid nodules and cancer achieved over the last 2 decades. Scientific reports on…”
Get more information

Molecular diagnostics of thyroid tumors by Nikiforov, Yuri E

“…Thyroid cancer is the most common type of endocrine malignancy and its incidence is steadily increasing. Papillary carcinoma and follicular carcinoma are the…”
Get full text

Thyroid carcinoma: molecular pathways and therapeutic targets by Nikiforov, Yuri E

“…Thyroid cancer is the most common malignant tumor of the endocrine system. The most frequent type of thyroid malignancy is papillary carcinoma. These tumors…”
Get full text

Molecular analysis of thyroid tumors by Nikiforov, Yuri E

“…In the recent years, a large number of molecular alterations in thyroid cancer has been discovered and characterized. Some of these markers may have…”
Get full text

Molecular genetics and diagnosis of thyroid cancer by Nikiforov, Yuri E, Nikiforova, Marina N

“…Knowledge of genetic alterations occurring in thyroid cancer has rapidly expanded in the past decade. This Review discusses genetic alterations in follicular…”
Get full text

Targeted Next-Generation Sequencing Panel (ThyroSeq) for Detection of Mutations in Thyroid Cancer by Nikiforova, Marina N, Wald, Abigail I, Roy, Somak, Durso, Mary Beth, Nikiforov, Yuri E

“…Objectives: Next-generation sequencing (NGS) allows for high-throughput sequencing analysis of large regions of the human genome. We explored the use of…”
Get full text

Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules by Nikiforova, Marina N., Mercurio, Stephanie, Wald, Abigail I., Barbi de Moura, Michelle, Callenberg, Keith, Santana‐Santos, Lucas, Gooding, William E., Yip, Linwah, Ferris, Robert L., Nikiforov, Yuri E.

“…BACKGROUND Molecular tests have clinical utility for thyroid nodules with indeterminate fine‐needle aspiration (FNA) cytology, although their performance…”
Get full text

Cytological features of “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” and their correlation with tumor histology by Maletta, Francesca, Massa, Federica, Torregrossa, Liborio, Duregon, Eleonora, Casadei, Gian Piero, Basolo, Fulvio, Tallini, Giovanni, Volante, Marco, Nikiforov, Yuri E., Papotti, Mauro

“…Among thyroid papillary carcinomas (PTCs), the follicular variant is the most common and includes encapsulated forms (EFVPTCs). Noninvasive EFVPTCs have very…”
Get full text

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer by Bible, Keith C, Kebebew, Electron, Brierley, James, Brito, Juan P, Cabanillas, Maria E, Clark, Jr, Thomas J, Di Cristofano, Antonio, Foote, Robert, Giordano, Thomas, Kasperbauer, Jan, Newbold, Kate, Nikiforov, Yuri E, Randolph, Gregory, Rosenthal, M Sara, Sawka, Anna M, Shah, Manisha, Shaha, Ashok, Smallridge, Robert, Wong-Clark, Carol K

“…Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Since the guidelines for the management of ATC by the American Thyroid…”
Get more information

Progress in Thyroid Cancer Genomics: A 40-Year Journey by Fagin, James A, Nikiforov, Yuri E

“…Very little was known about the molecular pathogenesis of thyroid cancer until the late 1980s. As part of the Centennial celebration of the American Thyroid…”
Get more information

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer by Haugen, Bryan R, Alexander, Erik K, Bible, Keith C, Doherty, Gerard M, Mandel, Susan J, Nikiforov, Yuri E, Pacini, Furio, Randolph, Gregory W, Sawka, Anna M, Schlumberger, Martin, Schuff, Kathryn G, Sherman, Steven I, Sosa, Julie Ann, Steward, David L, Tuttle, R Michael, Wartofsky, Leonard

“…Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's…”
Get more information

Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes by Ganly, Ian, Makarov, Vladimir, Deraje, Shyamprasad, Dong, YiYu, Reznik, Ed, Seshan, Venkatraman, Nanjangud, Gouri, Eng, Stephanie, Bose, Promita, Kuo, Fengshen, Morris, Luc G.T., Landa, Inigo, Carrillo Albornoz, Pedro Blecua, Riaz, Nadeem, Nikiforov, Yuri E., Patel, Kepal, Umbricht, Christopher, Zeiger, Martha, Kebebew, Electron, Sherman, Eric, Ghossein, Ronald, Fagin, James A., Chan, Timothy A.

“…The molecular foundations of Hürthle cell carcinoma (HCC) are poorly understood. Here we describe a comprehensive genomic characterization of 56 primary HCC…”
Get full text

Molecular diagnostics and predictors in thyroid cancer by Nikiforova, Marina N, Nikiforov, Yuri E

“…The accuracy of cancer detection in thyroid nodules by fine-needle aspiration (FNA) cytology and prognostication of thyroid cancer needs further improvement…”
Get more information

Clinical validation of the ThyroSeq v3 genomic classifier in thyroid nodules with indeterminate FNA cytology by Nikiforov, Yuri E., Baloch, Zubair W.

“…Molecular testing of thyroid fine‐needle aspiration specimens has been developed with the primary goals of resolving the uncertainty of indeterminate cytology…”
Get full text

Minireview : RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis by CIAMPI, Raffaele, NIKIFOROV, Yuri E

Get full text

Thyroid cancer in 2015: Molecular landscape of thyroid cancer continues to be deciphered by Nikiforov, Yuri E

Get full text

MicroRNA Expression Profiling of Thyroid Tumors: Biological Significance and Diagnostic Utility by Nikiforova, Marina N., Tseng, George C., Steward, David, Diorio, Donna, Nikiforov, Yuri E.

“…Objective: MicroRNA (miRNA) expression is deregulated in many types of human cancers. We sought to investigate the expression patterns of miRNA in all major…”
Get full text

NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States by Prasad, Manju L., Vyas, Monika, Horne, Matthew J., Virk, Renu K., Morotti, Raffaella, Liu, Zongzhi, Tallini, Giovanni, Nikiforova, Marina N., Christison‐Lagay, Emily R., Udelsman, Robert, Dinauer, Catherine A., Nikiforov, Yuri E.

“…BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma (PTC), has been recently reported in children. METHODS The histopathology…”
Get full text

Clinical and Morphologic Features of ETV6-NTRK3 Translocated Papillary Thyroid Carcinoma in an Adult Population Without Radiation Exposure by Seethala, Raja R, Chiosea, Simion I, Liu, Cheng Z, Nikiforova, Marina, Nikiforov, Yuri E

“…The ETV6-NTRK3 translocation characterizes a subset of radiation associated and pediatric papillary thyroid carcinomas (PTCs). We now describe the…”
Get full text

Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology by Nikiforov, Yuri E, Carty, Sally E, Chiosea, Simon I, Coyne, Christopher, Duvvuri, Umamaheswar, Ferris, Robert L, Gooding, William E, LeBeau, Shane O, Ohori, N Paul, Seethala, Raja R, Tublin, Mitchell E, Yip, Linwah, Nikiforova, Marina N

“…Fine-needle aspiration (FNA) cytology is a common approach to evaluate thyroid nodules. It offers definitive diagnosis of a benign or malignant nodule in the…”
Get more information