Search Results - "Niki, R"

Mild, Redox-Neutral Alkylation of Imines Enabled by an Organic Photocatalyst by Patel, Niki R, Kelly, Christopher B, Siegenfeld, Allison P, Molander, Gary A

“…An operationally simple, mild, redox-neutral method for the photoredox alkylation of imines is reported. Utilizing an inexpensive organic photoredox catalyst,…”
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Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp(3)-sp(2) Cross-Coupling by Tellis, John C, Kelly, Christopher B, Primer, David N, Jouffroy, Matthieu, Patel, Niki R, Molander, Gary A

“…The important role of transition metal-catalyzed cross-coupling in expanding the frontiers of accessible chemical territory is unquestionable. Despite…”
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Mechanistic Study of Silver-Catalyzed Decarboxylative Fluorination by Patel, Niki R, Flowers, Robert A

“…The silver-catalyzed fluorination of aliphatic carboxylic acids by Selectfluor in acetone/water provides access to fluorinated compounds under mild and…”
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Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis by Patel, Niki R, Kelly, Christopher B, Jouffroy, Matthieu, Molander, Gary A

“…Single-electron transmetalation via photoredox/nickel dual catalysis provides the opportunity for the construction of Csp3 –Csp2 bonds through the transfer of…”
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Aminomethylation of Aryl Halides Using α‑Silylamines Enabled by Ni/Photoredox Dual Catalysis by Remeur, Camille, Kelly, Christopher B, Patel, Niki R, Molander, Gary A

“…A protocol for the aminomethylation of aryl halides using α-silylamines via Ni/photoredox dual catalysis is described. The low oxidation potential of these…”
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Phenol Derivatives as Coupling Partners with Alkylsilicates in Photoredox/Nickel Dual Catalysis by Patel, Niki R, Molander, Gary A

“…Photoredox/nickel dual catalysis via single electron transmetalation allows coupling of Csp3 –Csp2 hybridized centers under mild conditions. A procedure for…”
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Design of an in vitro biocatalytic cascade for the manufacture of islatravir by Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao

“…Enzyme-catalyzed reactions have begun to transform pharmaceutical manufacturing, offering levels of selectivity and tunability that can dramatically improve…”
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Uncovering the Mechanism of the Ag(I)/Persulfate-Catalyzed Cross-Coupling Reaction of Arylboronic Acids and Heteroarenes by Patel, Niki R, Flowers, Robert A

“…The catalytic cross-coupling of arylboronic acids with pyridines through single-electron oxidation provides efficient access to substituted heterocycles…”
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Preparation of visible-light-activated metal complexes and their use in photoredox/nickel dual catalysis by Kelly, Christopher B, Patel, Niki R, Primer, David N, Jouffroy, Matthieu, Tellis, John C, Molander, Gary A

“…This protocol describes the synthesis of two photoredox catalysts, [Ir{dF(CF 3 ) 2 ppy} 2 (bpy)]PF 6 and [Ru(bpy) 3 ](PF 6 ) 2 , that are activated by visible…”
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Total Synthesis of Darobactin A by Nesic, Marko, Ryffel, David B., Maturano, Jonathan, Shevlin, Michael, Pollack, Scott R., Gauthier, Donald R., Trigo-Mouriño, Pablo, Zhang, Li-Kang, Schultz, Danielle M., McCabe Dunn, Jamie M., Campeau, Louis-Charles, Patel, Niki R., Petrone, David A., Sarlah, David

“…The collaborative total synthesis of darobactin A, a recently isolated antibiotic that selectively targets Gram-negative bacteria, has been accomplished in a…”
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Perspectives on Telephone and Video Communication in the Intensive Care Unit during COVID-19 by Kennedy, Niki R, Steinberg, Alexis, Arnold, Robert M, Doshi, Ankur A, White, Douglas B, DeLair, Will, Nigra, Karen, Elmer, Jonathan

“…During the coronavirus disease (COVID-19) pandemic, many intensive care units (ICUs) have shifted communication with patients' families toward chiefly…”
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Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone by Patel, Niki R., Nawrat, Christopher C., McLaughlin, Mark, Xu, Yingju, Huffman, Mark A., Yang, Hao, Li, Hongming, Whittaker, Aaron M., Andreani, Teresa, Lévesque, François, Fryszkowska, Anna, Brunskill, Andrew, Tschaen, David M., Maloney, Kevin M.

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Central Nervous System Infections Due to Coccidioidomycosis by Jackson, Niki R, Blair, Janis E, Ampel, Neil M

“…Coccidioidomycosis is a common infection in the western and southwestern United States as well as parts of Mexico and Central and South America and is due to…”
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Five‐Step Enantioselective Synthesis of Islatravir via Asymmetric Ketone Alkynylation and an Ozonolysis Cascade by Patel, Niki R., Huffman, Mark A., Wang, Xiao, Ding, Bangwei, McLaughlin, Mark, Newman, Justin A., Andreani, Teresa, Maloney, Kevin M., Johnson, Heather C., Whittaker, Aaron M.

“…A 5‐step enantioselective synthesis of the potent anti‐HIV nucleoside islatravir is reported. The highly efficient route was enabled by a novel…”
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O‑Benzyl Xanthate Esters under Ni/Photoredox Dual Catalysis: Selective Radical Generation and Csp3–Csp2 Cross-Coupling by Vara, Brandon A, Patel, Niki R, Molander, Gary A

“…Alkyl xanthate esters are perhaps best known for their use in deoxygenation chemistry. However, their use in cross-coupling chemistry has not been productive,…”
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Correction to “Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis” by Patel, Niki R, Kelly, Christopher B, Jouffroy, Matthieu, Molander, Gary A

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O -Benzyl Xanthate Esters under Ni/Photoredox Dual Catalysis: Selective Radical Generation and Csp 3 -Csp 2 Cross-Coupling by Vara, Brandon A, Patel, Niki R, Molander, Gary A

“…Alkyl xanthate esters are perhaps best known for their use in deoxygenation chemistry. However, their use in cross-coupling chemistry has not been productive,…”
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Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp3–sp2 Cross-Coupling by Tellis, John C, Kelly, Christopher B, Primer, David N, Jouffroy, Matthieu, Patel, Niki R, Molander, Gary A

“…The important role of transition metal-catalyzed cross-coupling in expanding the frontiers of accessible chemical territory is unquestionable. Despite…”
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Correction to “Uncovering the Mechanism of the Ag(I)/Persulfate-Catalyzed Cross-Coupling Reaction of Arylboronic Acids and Heteroarenes” by Patel, Niki R, Flowers, Robert A

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Genetic Etiology and Clinical Consequences of Complete and Incomplete Achromatopsia by Thiadens, Alberta A.H.J., MD, Slingerland, Niki W.R., MD, Roosing, Susanne, Ing, van Schooneveld, Mary J., MD, PhD, van Lith-Verhoeven, Janneke J.C., MD, PhD, van Moll-Ramirez, Norka, MD, van den Born, L. Ingeborgh, MD, PhD, Hoyng, Carel B., MD, PhD, Cremers, Frans P.M., PhD, Klaver, Caroline C.W., MD, PhD

“…Objective To investigate the genetic causes of complete and incomplete achromatopsia (ACHM) and assess the association between disease-causing mutations,…”
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