Search Results - "Nijland, Jeroen"
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A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum
Published in PloS one (12-06-2013)“…Profiling and structural elucidation of secondary metabolites produced by the filamentous fungus Penicillium chrysogenum and derived deletion strains were used…”
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Maltose accumulation-induced cell death in Saccharomyces cerevisiae
Published in FEMS yeast research (09-01-2024)“…Abstract Pretreatment of lignocellulose yields a complex sugar mixture that potentially can be converted into bioethanol and other chemicals by engineered…”
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3
Engineering of Pentose Transport in Saccharomyces cerevisiae for Biotechnological Applications
Published in Frontiers in bioengineering and biotechnology (29-01-2020)“…Lignocellulosic biomass yields after hydrolysis, besides the hexose D-glucose, D-xylose, and L-arabinose as main pentose sugars. In second generation…”
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Integrative Analysis of the Ethanol Tolerance of Saccharomyces cerevisiae
Published in International journal of molecular sciences (15-03-2023)“…Ethanol (EtOH) alters many cellular processes in yeast. An integrated view of different EtOH-tolerant phenotypes and their long noncoding RNAs (lncRNAs) is not…”
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The amino‐terminal tail of Hxt11 confers membrane stability to the Hxt2 sugar transporter and improves xylose fermentation in the presence of acetic acid
Published in Biotechnology and bioengineering (01-09-2017)“…ABSTRACT Hxt2 is a glucose repressed, high affinity glucose transporter of the yeast Saccharomyces cerevisiae and is subjected to high glucose induced…”
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Antimicrobial Resistance of Shigella flexneri in Pakistani Pediatric Population Reveals an Increased Trend of Third-Generation Cephalosporin Resistance
Published in Current microbiology (01-04-2022)“…The rapid emergence of resistance to third-generation cephalosporins in Shigella flexneri is crucial in pediatric shigellosis management. Limited studies have…”
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Molecular epidemiology of Shigella flexneri isolated from pediatrics in a diarrhea-endemic area of Khyber Pakhtunkhwa, Pakistan
Published in European journal of clinical microbiology & infectious diseases (01-05-2020)“…Shigella flexneri is considered as an important causative agent of Shigellosis causing diarrhea in the countries with a low socioeconomic status. No study has…”
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Improved Xylose Metabolism by a CYC8 Mutant of Saccharomyces cerevisiae
Published in Applied and environmental microbiology (01-06-2017)“…Engineering for the utilization of pentose sugars is an important goal for the production of second-generation bioethanol and biochemicals. However, lacks…”
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D-xylose accelerated death of pentose metabolizing Saccharomyces cerevisiae
Published in Biotechnology for biofuels (17-04-2023)“…Rapid and effective consumption of D-xylose by Saccharomyces cerevisiae is essential for cost-efficient cellulosic bioethanol production. Hence, heterologous…”
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Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum
Published in Nature biotechnology (01-10-2008)“…Penicillins and derived β-lactam antibiotics are essential in healthcare. To gain more insight into penicillin synthesis van den Berg and colleagues sequence…”
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Efficient, D-glucose insensitive, growth on D-xylose by an evolutionary engineered Saccharomyces cerevisiae strain
Published in FEMS yeast research (01-12-2019)“…Optimizing D-xylose consumption in Saccharomyces cerevisiae is essential for cost-efficient cellulosic bioethanol production. An evolutionary engineering…”
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Combined roles of exporters in acetic acid tolerance in Saccharomyces cerevisiae
Published in Biotechnology for biofuels (18-06-2022)“…Abstract Acetic acid is a growth inhibitor generated during alcoholic fermentation and pretreatment of lignocellulosic biomass, a major feedstock to produce…”
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D-glucose overflow metabolism in an evolutionary engineered high-performance D-xylose consuming Saccharomyces cerevisiae strain
Published in FEMS yeast research (01-02-2021)“…ABSTRACT Co-consumption of D-xylose and D-glucose by Saccharomyces cerevisiae is essential for cost-efficient cellulosic bioethanol production. There is a need…”
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Laboratory evolution of a glucose-phosphorylation-deficient, arabinose-fermenting S. cerevisiae strain reveals mutations in GAL2 that enable glucose-insensitive l-arabinose uptake
Published in FEMS yeast research (01-09-2018)“…Cas9-assisted genome editing was used to construct an engineered glucose-phosphorylation-negative S. cerevisiae strain, expressing the Lactobacillus…”
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15
Nonlinear Biosynthetic Gene Cluster Dose Effect on Penicillin Production by Penicillium chrysogenum
Published in Applied and Environmental Microbiology (01-11-2010)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Engineering of an endogenous hexose transporter into a specific D-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae
Published in Biotechnology for biofuels (2014)“…BACKGROUND: Engineering of Saccharomyces cerevisiae for the simultaneous utilization of hexose and pentose sugars is vital for cost-efficient cellulosic…”
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Metabolic engineering of β-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis
Published in Metabolic engineering (01-07-2012)“…Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor…”
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Expression of the transporter encoded by the cefT gene of Acremonium chrysogenum increases cephalosporin production in Penicillium chrysogenum
Published in Fungal genetics and biology (01-10-2008)“…By introduction of the cefEF genes of Acremonium chrysogenum and the cmcH gene of Streptomyces clavuligerus, Penicillium chrysogenum can be reprogrammed to…”
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Impact of velvet complex on transcriptome and penicillin G production in glucose-limited chemostat cultures of a β-lactam high-producing Penicillium chrysogenum strain
Published in Omics (Larchmont, N.Y.) (01-06-2012)“…The multicomponent global regulator Velvet complex has been identified as a key regulator of secondary metabolite production in Aspergillus and Penicillium…”
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An engineered cryptic Hxt11 sugar transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae
Published in Biotechnology for biofuels (02-11-2015)“…The yeast Saccharomyces cerevisiae is unable to ferment pentose sugars like d-xylose. Through the introduction of the respective metabolic pathway, S…”
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