Search Results - "Nijjar, Jagtar Singh"
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The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease
Published in Scientific reports (04-10-2021)“…To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory…”
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Journal Article -
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JAK inhibitors disrupt T cell-induced proinflammatory macrophage activation
Published in Rheumatic & musculoskeletal diseases open (01-01-2023)“…ObjectivesMacrophage subsets, activated by T cells, are increasingly recognised to play a central role in rheumatoid arthritis (RA) pathogenesis. Janus kinase…”
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Journal Article -
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Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis
Published in Rheumatology (Oxford, England) (01-09-2013)“…The pathogenesis of RA is a complex and ever-changing landscape but amid the chaos of the disease process we have found effective treatment regimes. However,…”
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Journal Article -
4
The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release
Published in Annals of the rheumatic diseases (01-12-2013)“…Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial…”
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Journal Article -
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Macrophages and cd4 t-cells in rheumatoid arthritis and their modulation by jak inhibitors
Published 01-01-2015“…Background: Rheumatoid arthritis (RA) is a chronic inflammatory arthritis that causes significant morbidity and mortality and has no cure. Although early…”
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Dissertation -
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Systemic Lupus Erythematosus
Published in The Autoimmune Diseases (01-01-2020)Get full text
Book Chapter