Search Results - "Niiya, Toshiyuki"
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Antiplatelet effects of hydroxychloroquine in patients with systemic lupus erythematosus evaluated by the total thrombus-formation analysis system (T-TAS)
Published in Lupus science & medicine (08-07-2024)“…ObjectivesHydroxychloroquine (HCQ) has been shown to reduce thrombotic events in patients with SLE. However, the antiplatelet effects of HCQ are only supported…”
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The G/G Genotype of a Resistin Single-Nucleotide Polymorphism at −420 Increases Type 2 Diabetes Mellitus Susceptibility by Inducing Promoter Activity through Specific Binding of Sp1/3
Published in American journal of human genetics (01-10-2004)“…Insulin resistance is a major cause of type 2 diabetes mellitus (T2DM). Resistin, an adipocyte-secreted hormone, antagonizes insulin. Transgenic mice that…”
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CLTC-ALK fusion as a primary event in congenital blastic plasmacytoid dendritic cell neoplasm
Published in Genes chromosomes & cancer (01-01-2014)“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a subtype of acute myeloid leukemia, affecting mainly the elderly. It is thought to be derived from…”
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Cutaneous Lesions of a Blastic Plasmacytoid Dendritic Cell Neoplasm
Published in Internal Medicine (01-01-2014)Get full text
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Impairment of protein C secretion in protein C-deficient patients carrying an Asp297 mutation
Published in International journal of hematology (01-08-2011)“…Issue Title: Including PIH Articles on Signaling and Transcription in the Development of Leukemia…”
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A new four-way variant t(5;17;15;20)(q33;q12;q22;q11.2) in acute promyelocytic leukemia
Published in International journal of hematology (01-10-2011)“…Acute promyelocytic leukemia (APL) is characterized by t(15;17)(q22;q21), which results in the fusion of the promyelocytic leukemia (PML) gene at 15q22 with…”
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Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis
Published in International journal of hematology (01-02-2011)“…Peripheral T-cell lymphoma (PTCL) is a biologically diverse lymphoid malignancy. The clinical aggressiveness associated with hemophagocytic syndrome (HS) is a…”
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Vasodilator-stimulated phosphoprotein (VASP) phosphorylation assay for platelet response to cilostazol
Published in Platelets (Edinburgh) (01-03-2011)“…Recent clinical trials have demonstrated that cilostazol, an antiplatelet drug competent to inhibit phosphodiesterase 3, is effective in secondary prevention…”
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Successful rituximab treatment in an elderly patient with recurrent thrombotic thrombocytopenic purpura
Published in Rinshō ketsueki (01-07-2016)“…An 81-year-old man presenting with fever, neurological symptoms, thrombocytopenia, and hemolytic anemia was diagnosed with acquired idiopathic thrombotic…”
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A complete deficiency of coagulation factor XIII A‐subunit due to a novel compound heterozygote of Ser 413 Leu missense and an nt 389 (ins G) frameshift mutation
Published in British journal of haematology (01-12-1999)“…Coagulation factor XIII consists of two A‐ and two B‐subunits, and either gene mutation can cause a complete deficiency. In a newborn patient with persistent…”
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A novel MYH9 mutation in a patient with MYH9 disorders and platelet size-specific effect of romiplostim on macrothrombocytopenia
Published in Annals of hematology (01-09-2015)Get full text
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Novel causative and neutral mutations in a patient with protein C deficiency
Published in Thrombosis research (01-05-2013)Get full text
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Severe immune thrombocytopenia secondary to Waldenström's macroglobulinemia with anti-GPIb/IX monoclonal IgM antibody
Published in Annals of hematology (01-04-2014)Get full text
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Cappuccino mutation in an autoimmune‐prone strain of mice suggests a role of platelet function in the progression of immune complex crescentic glomerulonephritis
Published in Arthritis and rheumatism (01-09-2006)“…Objective Crescent formation in the renal glomerulus is a typical manifestation of progressive glomerulopathy associated with fatal renal failure; therefore,…”
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Activation of mouse phosphodiesterase 3B gene promoter by adipocyte differentiation in 3T3-L1 cells
Published in FEBS letters (07-09-2001)“…Activation of phosphodiesterase (PDE) 3B reduces free fatty acid output from adipocytes. Induction of PDE3B gene expression by adipocyte differentiation could…”
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Systematic search for single nucleotide polymorphisms in the 5 ′ flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes
Published in Molecular genetics and metabolism (01-05-2003)“…The activation of phosphodiesterase 3B (PDE3B) reduces free fatty acid output from adipocytes. A reduced PDE3B gene expression could lead to insulin…”
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Novel causative and neutral mutations in a patient with protein C deficiency
Published in Thrombosis research (01-05-2013)Get full text
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Susceptibility of clinical bacterial isolates to aztreonam
Published in Japanese journal of antibiotics (01-09-1987)“…In vitro activities of 7 antimicrobial agents against organisms (474 strains) isolated from patients with various infections in Ehime University Hospital from…”
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Antibacterial activities of cefotiam against various pathogens isolated from clinical materials (author's transl)
Published in Japanese journal of antibiotics (01-04-1982)“…Bacteriological evaluation was made on cefotiam (CTM), a new broad-spectrum cephalosporin antibiotic, and the following results wer obtained. 1) CTM has shown…”
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