Search Results - "Niimi, Kaoru"
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Expression of the chrXq27.3 miRNA cluster in recurrent ovarian clear cell carcinoma and its impact on cisplatin resistance
Published in Oncogene (18-02-2021)“…Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian cancer and exhibits dismal prognosis due to chemoresistance. Moreover, only…”
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Clinical effects of cervical conization with positive margins in cervical cancer
Published in Scientific reports (02-12-2021)“…Radical surgery after cervical conization is a common approach for the treatment of cervical cancer. In some cases, disease progression is observed after…”
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Reproductive outcomes of 105 malignant ovarian germ cell tumor survivors: a multicenter study
Published in American journal of obstetrics and gynecology (01-10-2018)“…Malignant ovarian germ cell tumors usually occur in young women. Until the 1970s, before establishment of systemic chemotherapy, malignant ovarian germ cell…”
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Short tandem repeat analysis to identify the causative pregnancy of high-risk gestational trophoblastic neoplasia: Molar versus nonmolar pregnancy and its relation to the outcome
Published in Placenta (Eastbourne) (01-09-2021)“…Gestational trophoblastic neoplasia (GTN) include a group of malignant neoplasms that originate from the trophoblasts of placental tissue in molar or nonmolar…”
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Akt-Girdin signaling in cancer-associated fibroblasts contributes to tumor progression
Published in Cancer research (Chicago, Ill.) (01-03-2015)“…PI3K-Akt signaling is critical for the development, progression, and metastasis of malignant tumors, but its role in the tumor microenvironment has been…”
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Evaluation of a routine second curettage for hydatidiform mole: a cohort study
Published in International journal of clinical oncology (01-06-2020)“…Objective The aim of this study was to evaluate routine second curettage for hydatidiform mole (HM) by comparing the characteristics and outcomes of developing…”
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A combination of circulating miRNAs for the early detection of ovarian cancer
Published in Oncotarget (27-10-2017)“…Ovarian cancer is the leading cause of gynecologic cancer mortality, due to the difficulty of early detection. Current screening methods lack sufficient…”
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Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis
Published in Matrix biology (01-05-2022)“…•In patients with ovarian cancer, peritoneal mesothelial cells are transformed into cancer-associated mesothelial cells via mesenchymal transition and form a…”
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The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia
Published in International journal of clinical oncology (01-01-2020)“…Objective This study aimed to evaluate the efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide, and actinomycin D (MEA) for patients who…”
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Efficacy of medroxyprogesterone acetate treatment and retreatment for atypical endometrial hyperplasia and endometrial cancer
Published in The journal of obstetrics and gynaecology research (01-01-2018)“…Aim Medroxyprogesterone acetate (MPA) is used to preserve fertility in patients with Grade 1 endometrial cancer without myometrial invasion (G1EA) and those…”
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Safety assessments and clinical features of PARP inhibitors from real-world data of Japanese patients with ovarian cancer
Published in Scientific reports (01-06-2024)“…Poly (ADP-ribose) polymerase inhibitors have been increasingly used in ovarian cancer treatment. However, the real-world safety data of these drugs in Japanese…”
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The Preoperative Prognostic Nutritional Index for the Prediction of Outcomes in Patients with Early-Stage Ovarian Clear Cell Carcinoma
Published in Scientific reports (28-04-2020)“…The prognostic nutritional index (PNI), which reflects preoperative malnutrition, is useful for predicting the incidence of postoperative complications and has…”
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Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation
Published in The journal of obstetrics and gynaecology research (01-07-2023)“…This study analyzed a 63‐year‐old woman with hereditary BRCA1 mutation. She underwent interval debulking surgery after neoadjuvant chemotherapy for high‐grade…”
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A case of complete remission of intractable gestational choriocarcinoma with subsequent chemotherapy after pembrolizumab
Published in Taiwanese journal of obstetrics & gynecology (01-09-2023)“…Gestational choriocarcinoma is a gestational trophoblastic neoplasia (GTN) that originates from abnormal trophoblast proliferation. Although chemotherapy is…”
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KIF20A expression as a prognostic indicator and its possible involvement in the proliferation of ovarian clear‑cell carcinoma cells
Published in Oncology reports (01-07-2018)“…Kinesin family member 20A (KIF20A), which is involved in cytokinesis and intracellular transportation, has been recently reported to be upregulated in several…”
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Establishment and characterization of a non-gestational choriocarcinoma patient-derived xenograft model
Published in BMC cancer (13-11-2023)“…Abstract Background Non-gestational choriocarcinoma (NGC) is a rare subtype of malignant germ cell tumour and there is no consensus on its treatment. The lack…”
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The role of additional hysterectomy after concurrent chemoradiation for patients with locally advanced cervical cancer
Published in International journal of clinical oncology (01-02-2020)“…Background The standard treatment for cervical cancer is chemoradiation although some patients showed treatment resistance. The purpose of this study was to…”
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Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells
Published in Oncotarget (21-11-2017)“…ZEB1, a member of the zinc-finger E-box binding homeobox family, is considered to play a crucial role in cancer progression and metastasis. In the current…”
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Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells
Published in Cancer science (01-05-2014)“…Human REV7 (also known as MAD2L2 and MAD2B) is involved in DNA repair, cell cycle regulation, gene transcription, and carcinogenesis. In this study, we…”
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