Search Results - "Niikura, Kenichi"

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo by Niikura, Kenichi, Matsunaga, Tatsuya, Suzuki, Tadaki, Kobayashi, Shintaro, Yamaguchi, Hiroki, Orba, Yasuko, Kawaguchi, Akira, Hasegawa, Hideki, Kajino, Kiichi, Ninomiya, Takafumi, Ijiro, Kuniharu, Sawa, Hirofumi

“…This paper demonstrates how the shape and size of gold nanoparticles (AuNPs) affect immunological responses in vivo and in vitro for the production of…”
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Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs by Sekimukai, Hanako, Iwata‐Yoshikawa, Naoko, Fukushi, Shuetsu, Tani, Hideki, Kataoka, Michiyo, Suzuki, Tadaki, Hasegawa, Hideki, Niikura, Kenichi, Arai, Katsuhiko, Nagata, Noriyo

“…The spike (S) protein of coronavirus, which binds to cellular receptors and mediates membrane fusion for cell entry, is a candidate vaccine target for blocking…”
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Surface engineering of nanoparticles for therapeutic applications by Kobayashi, Kenya, Wei, Jinjian, Iida, Ryo, Ijiro, Kuniharu, Niikura, Kenichi

“…Nanoparticles with a diameter of <100 nm are regarded as potential medical materials, as this size allows nanoparticles to circulate in vivo and possibly reach…”
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Yolk/Shell Assembly of Gold Nanoparticles by Size Segregation in Solution by Wei, Jinjian, Niikura, Kenichi, Higuchi, Takeshi, Kimura, Takashi, Mitomo, Hideyuki, Jinnai, Hiroshi, Joti, Yasumasa, Bessho, Yoshitaka, Nishino, Yoshinori, Matsuo, Yasutaka, Ijiro, Kuniharu

“…We demonstrate that binary mixtures of small and large gold nanoparticles (GNPs) (5/15, 5/30, 10/30, and 15/30 nm in diameter) in the presence of a…”
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Gold Nanoparticle Arrangement on Viral Particles through Carbohydrate Recognition: A Non-Cross-Linking Approach to Optical Virus Detection by Niikura, Kenichi, Nagakawa, Keita, Ohtake, Noriko, Suzuki, Tadaki, Matsuo, Yasutaka, Sawa, Hirofumi, Ijiro, Kuniharu

“…We propose a new approach to optical virus detection based on the spatial assembly of gold nanoparticles on the surface of viruses. Since JC virus-like…”
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Supramolecular Conjugation between 18-Crown 6-Ether and Tannic Acid with Unique pH Responsiveness by Endo, Saki, Mahiro Sarai, Hatano, Akihiko, Niikura, Kenichi

“…We demonstrate that 18-crown 6-ether interacts with tannic acid to form particles at pH 7.4 that degrade at pH 5. Tannic acid has been used in biomaterials on…”
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DNA-modulated photo-transformation of AgCl to silver nanoparticles: visiting the formation mechanism by Wang, Guoqing, Mitomo, Hideyuki, Matsuo, Yasutaka, Niikura, Kenichi, Maeda, Mizuo, Ijiro, Kuniharu

“…[Display omitted] Solution-phase synthesis and post-synthetic bio-modification have continued to play a dominant role in preparation of nanostructured…”
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Shape-dependent adjuvanticity of nanoparticle-conjugated RNA adjuvants for intranasal inactivated influenza vaccines by Tazaki, Taiyu, Tabata, Koshiro, Ainai, Akira, Ohara, Yuki, Kobayashi, Shintaro, Ninomiya, Takafumi, Orba, Yasuko, Mitomo, Hideyuki, Nakano, Tetsuo, Hasegawa, Hideki, Ijiro, Kuniharu, Sawa, Hirofumi, Suzuki, Tadaki, Niikura, Kenichi

“…Intranasal inactivated influenza vaccines can elicit mucosal immune responses that protect against virus infection. For the development of intranasal…”
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Multidentate coating of maltooligosaccharides allows nuclear import of nanoparticles by Niikura, Kenichi

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Nanoscale uniformity in the active tuning of a plasmonic array by polymer gel volume change by Hamajima, Satoru, Mitomo, Hideyuki, Tani, Takeharu, Matsuo, Yasutaka, Niikura, Kenichi, Naya, Masayuki, Ijiro, Kuniharu

“…Active plasmonic tuning is an attractive but challenging research subject, leading to various promising applications. As one of the approaches, nanostructures…”
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Inspiration from chemical photography: accelerated photoconversion of AgCl to functional silver nanoparticles mediated by DNA by Wang, Guoqing, Nishio, Takashi, Sato, Masato, Ishikawa, Ayako, Nambara, Katsuyuki, Nagakawa, Keita, Matsuo, Yasutaka, Niikura, Kenichi, Ijiro, Kuniharu

“…We demonstrate a facile approach for converting AgCl to functional silver nanoparticles (AgNPs) via photoreduction in the presence of DNA. The resulting AgNPs…”
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Improving in Vivo Hepatic Transfection Activity by Controlling Intracellular Trafficking: The Function of GALA and Maltotriose by Akita, Hidetaka, Masuda, Tomoya, Nishio, Takashi, Niikura, Kenichi, Ijiro, Kuniharu, Harashima, Hideyoshi

“…The successful control of intracellular trafficking (i.e., endosomal escape and nuclear delivery) is prerequisite for the development of a gene delivery…”
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Fabrication of a Novel Cell Culture System Using DNA-Grafted Substrates and DNase by Mitomo, Hideyuki, Eguchi, Asumi, Suzuki, Yasunobu, Matsuo, Yasutaka, Niikura, Kenichi, Nakazawa, Kohji, Ijiro, Kuniharu

“…In conventional cell culture systems, trypsin is generally used for cell harvesting. However, trypsin damages the cells due to the nonselective degradation of…”
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Cysteine residues in the major capsid protein, Vp1, of the JC virus are important for protein stability and oligomer formation by Kobayashi, Shintaro, Suzuki, Tadaki, Igarashi, Manabu, Orba, Yasuko, Ohtake, Noriko, Nagakawa, Keita, Niikura, Kenichi, Kimura, Takashi, Kasamatsu, Harumi, Sawa, Hirofumi

“…The capsid of the human polyomavirus JC virus (JCV) consists of 72 pentameric capsomeres of a major structural protein, Vp1. The cysteine residues of the…”
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High-Throughput Protein Glycomics: Combined Use of Chemoselective Glycoblotting and MALDI-TOF/TOF Mass Spectrometry by Nishimura, Shin-Ichiro, Niikura, Kenichi, Kurogochi, Masaki, Matsushita, Takahiko, Fumoto, Masataka, Hinou, Hiroshi, Kamitani, Ryousuke, Nakagawa, Hiroaki, Deguchi, Kisaburo, Miura, Nobuaki, Monde, Kenji, Kondo, Hirosato

“…Common oligosaccharides and aldehyde‐attached glycoproteins derived from enzymatic modifications can be captured by glycoblotting based on oxylamino‐containing…”
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Influence of Hydrophobic Structures on the Plasma Membrane Permeability of Lipidlike Molecules by Niikura, Kenichi, Nambara, Katsuyuki, Okajima, Takaharu, Matsuo, Yasutaka, Ijiro, Kuniharu

“…A series of FITC-labeled hydrophobic molecules (1−8) were prepared, and their cellular uptakes have been investigated using cell-cycle-synchronized HeLa cells…”
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Kinetic Measurements of DNA Hybridization on an Oligonucleotide-Immobilized 27-MHz Quartz Crystal Microbalance by Okahata, Yoshio, Kawase, Masanori, Niikura, Kenichi, Ohtake, Fuyuka, Furusawa, Hiroyuki, Ebara, Yasuhito

“…A highly sensitive 27-MHz quartz-crystal microbalance, on which a 10−30-mer oligonucleotide was immobilized as a probe molecule, was employed to detect…”
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Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription by Masuda, Tomoya, Akita, Hidetaka, Niikura, Kenichi, Nishio, Takashi, Ukawa, Masami, Enoto, Kaoru, Danev, Radostin, Nagayama, Kuniaki, Ijiro, Kuniharu, Harashima, Hideyoshi

“…Abstract Lipid envelope-type nanoparticles are promising carriers for gene delivery. The modification of liposomes with polyethyleneglycol (PEG) can often be…”
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pH-Dependent Network Formation of Quantum Dots and Fluorescent Quenching by Au Nanoparticle Embedding by Sekiguchi, Shota, Niikura, Kenichi, Iyo, Naoki, Matsuo, Yasutaka, Eguchi, Asumi, Nakabayashi, Takakazu, Ohta, Nobuhiro, Ijiro, Kuniharu

“…A simple approach to the creation of colloidal assemblies is in high demand for the development of functional devices. Here, we present the preparation of…”
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DNA Brush-Directed Vertical Alignment of Extensive Gold Nanorod Arrays with Controlled Density by Nakamura, Satoshi, Mitomo, Hideyuki, Aizawa, Miho, Tani, Takeharu, Matsuo, Yasutaka, Niikura, Kenichi, Pike, Andrew, Naya, Masayuki, Shishido, Atsushi, Ijiro, Kuniharu

“…Control over the orientation of metal nanorods is important for both fundamental and applied research. We show that gold nanorods (GNRs) can be aligned in a…”
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