Search Results - "Nii, Keiji"

Acid-Catalyzed Reactions of Sarcophytoxide, a Marine Cembranoid: An Apparently Enantio-Directive Reaction, Unusual Products and Stereochemical Reconsideration of Epoxide–Ketone Rearrangement by Nii, Keiji, Tagami, Keiko, Kijima, Masaru, Munakata, Tatsuo, Ooi, Takashi, Kusumi, Takenori

“…Perchloric acid treatment of sarcophytoxide, a marine cembranoid possessing an epoxide, brought about epoxide–ketone rearrangement affording ketones. When the…”
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Unusual Transannular Cyclization Products of Sarcophytoxide, a 14-Membered Marine Cembranoid:  Anomalous Stereochemistry of Epoxide−Ketone Rearrangement by Nii, Keiji, Tagami, Keiko, Matsuoka, Keisuke, Munakata, Tatsuo, Ooi, Takashi, Kusumi, Takenori

“…Treatment of sarcophytoxide with trimethylsilyl trifluoromethanesulfonate afforded an aromatic ketone as an unusual cyclization product. The modified Mosher's…”
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Broadly Applicable and Comprehensive Synthetic Method for N‑Alkyl-Rich Drug-like Cyclic Peptides by Nomura, Kenichi, Hashimoto, Satoshi, Takeyama, Ryuuichi, Tamiya, Minoru, Kato, Tatsuya, Muraoka, Terushige, Kage, Mirai, Nii, Keiji, Kotake, Kenichiro, Iida, Satomi, Emura, Takashi, Tanada, Mikimasa, Iikura, Hitoshi

“…We report a versatile and durable method for synthesizing highly N-alkylated drug-like cyclic peptides. This is the first reported method for synthesizing such…”
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Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display by Kage, Mirai, Hayashi, Ryuji, Matsuo, Atsushi, Tamiya, Minoru, Kuramoto, Shino, Ohara, Kazuhiro, Irie, Machiko, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Kotake, Tomoya, Takeyama, Ryuuichi, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Hashimoto, Satoshi, Kawada, Hatsuo, Nishimura, Yoshikazu, Nii, Keiji, Sase, Hitoshi, Ohta, Atsushi, Kojima, Tetsuo, Iikura, Hitoshi, Tanada, Mikimasa, Shiraishi, Takuya

“…[Display omitted] Cyclic peptides are attracting attention as therapeutic agents due to their potential for oral absorption and easy access to tough…”
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Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor by Tanada, Mikimasa, Tamiya, Minoru, Matsuo, Atsushi, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Irie, Machiko, Kotake, Tomoya, Takeyama, Ryuuichi, Kawada, Hatsuo, Hayashi, Ryuji, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Kage, Mirai, Hashimoto, Satoshi, Nii, Keiji, Sase, Hitoshi, Ohara, Kazuhiro, Ohta, Atsushi, Kuramoto, Shino, Nishimura, Yoshikazu, Iikura, Hitoshi, Shiraishi, Takuya

“…Cyclic peptides as a therapeutic modality are attracting a lot of attention due to their potential for oral absorption and accessibility to intracellular tough…”
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Acid-Catalyzed Reactions of Sarcophytoxide, a Marine Cembranoid by Nii, Keiji, Tagami, Keiko, Kijima, Masaru, Munakata, Tatsuo, Ooi, Takashi, Kusumi, Takenori

“…Perchloric acid treatment of sarcophytoxide, a marine cembranoid possessing an epoxide, brought about epoxide-ketone rearrangement affording ketones. When the…”
Get full text