Search Results - "Nihei, Ken"
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1
A natural diphenolic glucoside, sonnerphenolic C: Chemical synthesis, structural revision, redox transformation, and identification as an antioxidant
Published in Tetrahedron (30-05-2024)“…To investigate the redox o-hydroxylation of epirhododendrin (1) with tyrosinase and vitamin C, the possible product, sonnerphenolic C (2), and its epimer,…”
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2
Benzonitriles as tyrosinase inhibitors with hyperbolic inhibition manner
Published in International journal of biological macromolecules (15-07-2019)“…As a novel mushroom tyrosinase inhibitor, 4-methoxybenzonitrile (anisnitrile) was identified (IC50 = 111.1 μM) with hyperbolic inhibition manner. The…”
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3
Tyrosinase Inhibition by 4-Substituted Benzaldehydes with Electron-Withdrawing Groups
Published in Applied biochemistry and biotechnology (01-08-2020)“…The oxidation of 4- t -butylcatechol catalyzed by mushroom tyrosinase was inhibited by 4-bromobenzaldehyde, 4-chlorobenzaldehyde, 4-fluorobenzaldehyde,…”
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4
Synthesis, structural revision, and tyrosinase inhibitory activity of proposed phloretin-4-O-β-D-glucopyranoside from Homalium stenophyllum
Published in Natural product research (03-04-2022)“…Phloretin-4-O-β-D-glucopyranoside (1), isolated from Homalium stenophyllum, was synthesized for the first time through aldol condensation and Schmidt…”
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5
Resorcinol alkyl glucosides as potent tyrosinase inhibitors
Published in Bioorganic & medicinal chemistry letters (15-01-2019)“…[Display omitted] •Resorcinol alkyl glucosides 7–12 were developed as novel tyrosinase inhibitors.•The inhibitory activity of 7–12 increased with the length of…”
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6
Total synthesis of apios isoflavones and investigation of their tyrosinase inhibitory activity
Published in Tetrahedron (11-10-2019)“…Apios isoflavone glucosides 1 and 2 were synthesized for the first time via Friedel–Crafts reaction, Bischler–Napieralski-type cyclization, and phase-transfer…”
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7
Substituent effect of benzaldehydes on tyrosinase inhibition
Published in Plant physiology and biochemistry (01-03-2017)“…Benzaldehyde inhibited the oxidation of 4-t-butylcatechol catalyzed by mushroom tyrosinase with an IC50 of 31.0 μM. The inhibition kinetics analyzed by Dixon…”
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8
Molecular design of potent, hydrophilic tyrosinase inhibitors based on the natural dihydrooxyresveratrol skeleton
Published in Carbohydrate research (15-01-2019)“…In this study, dihydrooxyresveratrol glucosides 3–6 were synthesized for the first time to the best of our knowledge by the Wittig reaction and Schmidt…”
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9
Chemical synthesis and tyrosinase-inhibitory activity of isotachioside and its related glycosides
Published in Carbohydrate research (30-07-2018)“…Isotachioside (1) and its related natural product 2 are isolated from Isotachis japonica and Protea neriifolia, respectively, and are categorized as analogs of…”
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10
Rhododendrol glycosides as stereospecific tyrosinase inhibitors
Published in Bioorganic & medicinal chemistry (15-10-2015)“…[Display omitted] Rhododendrol derivatives 3–12 have been synthesized in six steps, including aldol condensation and/or trichloroacetimidate glycosylation as…”
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11
Inhibitory effects of cardols and related compounds on superoxide anion generation by xanthine oxidase
Published in Food chemistry (01-01-2015)“…•Cardols (5-alkylresorcinols) and related compounds were synthesized.•They did not competitively inhibit uric acid formation by xanthine oxidase.•Some of them…”
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12
Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps
Published in Peptides (New York, N.Y. : 1980) (01-08-2021)“…•Seven peptide components in the venoms of solitary sphecid wasps, Sphex argentatus argentatus and Isodontia harmandi were isolation and chemical and…”
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13
Chemical synthesis, redox transformation, and identification of sonnerphenolic C, an antioxidant in Acer nikoense
Published in Bioorganic & medicinal chemistry letters (15-04-2017)“…[Display omitted] Sonnerphenolic C (3), which was predicted in a redox product of epirhododendrin (1) isolated from Acer nikoense, was synthesized for the…”
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14
Extraction of strawberry leaves with supercritical carbon dioxide and entrainers: Antioxidant capacity, total phenolic content, and inhibitory effect on uric acid production of the extract
Published in Food and bioproducts processing (01-09-2019)“…[Display omitted] •Extraction of strawberry leaf was conducted with supercritical CO2 and entrainers.•Ethanol, acetone and water improved the antioxidant…”
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15
Effect of temperature and pressure on the extraction of strawberry receptacles with a mixture of supercritical carbon dioxide and entrainers
Published in The Journal of supercritical fluids (01-12-2017)“…[Display omitted] •Extraction of strawberries was conducted with supercritical CO2 and entrainers.•Ethanol, acetone and water improved the antioxidant…”
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16
Total synthesis of (−)-ribesin B and its structural revision
Published in Tetrahedron letters (12-01-2023)“…[Display omitted] A highly symmetric dihydrofuran lignan, ribesin B (1), isolated from the leaves of Ribes nigrum, was synthesized via a process whereby the…”
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17
Chemical synthesis and tyrosinase inhibitory activity of resorcinol alkyl glucosides, hydroxyalkyl resorcinols, and alkyl resorcinols
Published in Journal of molecular structure (15-11-2022)“…•Resorcinol alkyl glucosides 7–12 were synthesized to develop tyrosinase inhibitors.•Hydroxyalkyl resorcinols 13–18 and alkyl resorcinols 19–24 were also…”
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18
Dihydroresveratrol cellobioside and xylobioside as effective melanogenesis activators
Published in Carbohydrate research (21-12-2016)“…Dihydroresveratrol cellobioside and xylobioside, whose structures were designed based on that of the naturally occurring melanogenesis-controlling agent…”
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19
Systematic approach to the chemical synthesis of arabidopyrones, the unique α-pyrones of Arabidopsis metabolites
Published in Synthetic communications (01-10-2020)“…Total synthesis of two arabidopyrones, iso-arabidopyl alcohol (1) and iso-arabidopic acid (2) isolated from Arabidopsis thaliana was achieved for the first…”
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20
Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata
Published in Toxins (10-12-2021)“…Venoms of solitary wasps are utilized for prey capture (insects and spiders), paralyzing them with a stinger injection to be offered as food for their larvae…”
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