Search Results - "Nieweg, Katja"

Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats by Nieweg, Katja, Schaller, Hubert, Pfrieger, Frank W

“…Neurons have a high demand for cholesterol to develop and maintain membrane-rich structures like axons, dendrites and synapses, but it remains unclear, whether…”
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Asymmetric N-cadherin expression results in synapse dysfunction, synapse elimination, and axon retraction in cultured mouse neurons by Pielarski, Kim N, van Stegen, Bernd, Andreyeva, Aksana, Nieweg, Katja, Jüngling, Kay, Redies, Christoph, Gottmann, Kurt

“…Synapse elimination and pruning of axon collaterals are crucial developmental events in the refinement of neuronal circuits. While a control of synapse…”
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Episomal plasmid-based generation of an iPSC line from a 79-year-old individual carrying the APOE4/4 genotype: i11001 by Zulfiqar, Shadaan, Fritz, Barbara, Nieweg, Katja

“…In this study, lymphoblastoid cells derived from a 79-year old individual with a history of progressive presenile dementia, were used to generate iPS cells,…”
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Glia-induced neuronal differentiation by transcriptional regulation by Göritz, Christian, Thiebaut, Renaud, Tessier, Luc-Henri, Nieweg, Katja, Moehle, Christoph, Buard, Isabelle, Dupont, Jean-Luc, Schurgers, Leon J., Schmitz, Gerd, Pfrieger, Frank W.

“…There is increasing evidence that different phases of brain development depend on neuron–glia interactions including postnatal key events like synaptogenesis…”
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Contribution of astrocytes to metabolic dysfunction in the Alzheimer's disease brain by Zulfiqar, Shadaan, Garg, Pretty, Nieweg, Katja

“…Historically considered as accessory cells to neurons, there is an increasing interest in the role of astrocytes in normal and pathological conditions…”
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Astrocyte lineage cells are essential for functional neuronal differentiation and synapse maturation in human iPSC‐derived neural networks by Klapper, Simon D., Garg, Pretty, Dagar, Sushma, Lenk, Kerstin, Gottmann, Kurt, Nieweg, Katja

“…Human astrocytes differ dramatically in cell morphology and gene expression from murine astrocytes. The latter are well known to be of major importance in the…”
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Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1 by Kurth, Vanessa, Ogorek, Isabella, Münch, Carolina, Lopez-Rios, Javier, Ousson, Solenne, Lehmann, Sandra, Nieweg, Katja, Roebroek, Anton J.M., Pietrzik, Claus U., Beher, Dirk, Weggen, Sascha

“…Presenilin-1 (PSEN1) is the catalytic subunit of the intramembrane protease γ-secretase and undergoes endoproteolysis during its maturation. Heterozygous…”
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Episomal plasmid-based generation of an iPSC line from an 83-year-old individual carrying the APOE4/4 genotype: i10984 by Zulfiqar, Shadaan, Fritz, Barbara, Nieweg, Katja

“…In this study, lymphoblastoid cells derived from a 83-year old individual with a 15year history of progressive presenile dementia, were used to generate iPS…”
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C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β by ANDREYEVA, Aksana, NIEWEG, Katja, HORSTMANN, Katharina, KLAPPER, Simon, MÜLLER-SCHIFFMANN, Andreas, KORTH, Carsten, GOTTMANN, Kurt

“…The aetiology of Alzheimer's disease is thought to include functional impairment of synapses and synapse loss as crucial pathological events leading to…”
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Embryonic stem cells stably expressing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation by Leschik, Julia, Eckenstaler, Robert, Nieweg, Katja, Lichtenecker, Petra, Brigadski, Tanja, Gottmann, Kurt, Lessmann, Volkmar, Lutz, Beat

“…Brain-derived neurotrophic factor (BDNF) is known to be a crucial regulator of neuronal survival and synaptic plasticity in the mammalian brain. Furthermore,…”
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mESC-based in vitro differentiation models to study vascular response and functionality following genotoxic insults by Hennicke, Tatiana, Nieweg, Katja, Brockmann, Nicole, Kassack, Matthias U, Gottmann, Kurt, Fritz, Gerhard

“…Because of high exposure to systemic noxae, vascular endothelial cells (EC) have to ensure distinct damage defense and regenerative mechanisms to guarantee…”
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Characterization of 4-Aminopyridine-induced network plasticity in rat cortical and human iPSC-derived neuronal cultures by Gaye, Tanri ver, Katja, Nieweg

“…Abstract only…”
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Embryonic stem cells stably expressing BDNF–GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation by Leschik, Julia, Eckenstaler, Robert, Nieweg, Katja, Lichtenecker, Petra, Brigadski, Tanja, Gottmann, Kurt, Lessmann, Volkmar, Lutz, Beat

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Stably BDNF-GFP expressing embryonic stem cells exhibit a BDNF release-dependent enhancement of neuronal differentiation by Leschik, Julia, Eckenstaler, Robert, Nieweg, Katja, Lichtenecker, Petra, Brigadski, Tanja, Gottmann, Kurt, Leßmann, Volkmar, Lutz, Beat

“…Brain-derived neurotrophic factor (BDNF) is known to be a crucial regulator of neuronal survival and synaptic plasticity in the mammalian brain. Furthermore,…”
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Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats by Nieweg, Katja, Schaller, Hubert, Pfrieger, Frank

“…Neurons have a high demand for cholesterol to develop and maintain membrane-rich structures like axons, dendrites and synapses, but it remains unclear, whether…”
Get full text