Search Results - "Nieuwenhuizen, L"

How to Distinguish Isodesmic from Cooperative Supramolecular Polymerisation by Smulders, Maarten M. J., Nieuwenhuizen, Marko M. L., de Greef, Tom F. A., van der Schoot, Paul, Schenning, Albertus P. H. J., Meijer, E. W.

“…To study the supramolecular polymerisation mechanisms of a self‐assembling system, concentration‐ and temperature‐dependent measurements can both be used to…”
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Hydrogen-bonded supramolecular polymers as self-healing hydrogels: Effect of a bulky adamantyl substituent in the ureido-pyrimidinone monomer by Chirila, Traian V., Lee, Hui Hui, Oddon, Mathieu, Nieuwenhuizen, Marko M. L., Blakey, Idriss, Nicholson, Timothy M.

“…ABSTRACT In an attempt to generate supramolecular assemblies able to function as self‐healing hydrogels, a novel ureido‐pyrimidinone (UPy) monomer, 2‐(N…”
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Dilution-Induced Self-Assembly of Porphyrin Aggregates: A Consequence of Coupled Equilibria by Helmich, Floris, Lee, Cameron C, Nieuwenhuizen, Marko M.L, Gielen, Jeroen C, Christianen, Peter C.M, Larsen, Antje, Fytas, George, Leclère, Philippe E.L.G, Schenning, Albertus P.H.J, Meijer, E.W

“…Piggy‐back porphyrins: The presence of a Lewis base remarkably affects the cooperative self‐assembly of zinc porphyrins. Driven by the susceptibility of the…”
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Mechanically Induced Gelation of a Kinetically Trapped Supramolecular Polymer by Teunissen, Abraham J. P, Nieuwenhuizen, Marko M. L, Rodríguez-Llansola, Fransico, Palmans, Anja R. A, Meijer, E. W

“…The stimuli-induced gelation of a urethane-functionalized ditopic ureidopyrimidinone (UPy) compound is presented, and the mechanism by which the gelation…”
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Maternal and neonatal bleeding complications in relation to peripartum management in women with Von Willebrand disease: A systematic review by Punt, M.C., Waning, M.L., Mauser-Bunschoten, E.P., Kruip, M.J.H.A., Eikenboom, J., Nieuwenhuizen, L., Makelburg, A.B.U., Driessens, M.H.E., Duvekot, J.J., Peters, M., Middeldorp, J.M., Bloemenkamp, K.W.M., Schutgens, R.E.G., Lely, A.T., Van Galen, K.P.M.

“…Women with Von Willebrand disease (VWD) have an increased risk of developing postpartum hemorrhage (PPH). Our aim is to evaluate peripartum management…”
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Impact of organizational context on patient outcomes in a proactive primary care program:a longitudinal observational study by Smit, Linda C, De Wit, Niek J, Nieuwenhuizen, Meggie L, Schuurmans, Marieke J, Bleijenberg, Nienke

“…Abstract Background The effectiveness of health care interventions is co-determined by contextual factors. Unknown is the extent of this impact on patient…”
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Maternal and neonatal bleeding complications in relation to peripartum management in hemophilia carriers: A systematic review by Punt, M.C., Waning, M.L., Mauser-Bunschoten, E.P., Kruip, M.J.H.A., Eikenboom, J., Nieuwenhuizen, L., Makelburg, A.B.U., Driessens, M.H.E., Duvekot, J.J., Peters, M., Middeldorp, J.M., Bloemenkamp, K.W.M., Schutgens, R.E.G., Lely, A.T., van Galen, K.P.M.

“…Currently, there is no consensus on the optimal management to prevent postpartum hemorrhage (PPH) in hemophilia carriers. We aimed to evaluate peripartum…”
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An unusual complication of pregnancy by van Erven, B, de Wit-Zuurendonk, L, Laupman-Koedam, E, Nieuwenhuizen, L

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Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders by Atiq, F., Saes, J.L., Punt, M.C., van Galen, K.P.M., Schutgens, R.E.G., Meijer, K., Cnossen, M.H., Laros-Van Gorkom, B.A.P., Peters, M., Nieuwenhuizen, L., Kruip, M.J.H.A., de Meris, J., van der Bom, J.G., van der Meer, F.J.M., Fijnvandraat, K., Kruis, I.C., van Heerde, W.L., Eikenboom, H.C.J., Leebeek, Frank W.G., Schols, S.E.M.

“…In recent years, more awareness is raised about sex-specific dilemmas in inherited bleeding disorders. However, no large studies have been performed to assess…”
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Identification and expression of iron regulators in human synovium: evidence for upregulation in haemophilic arthropathy compared to rheumatoid arthritis, osteoarthritis, and healthy controls by Nieuwenhuizen, L., Schutgens, R. E.G., van Asbeck, B. S., Wenting, M. J., van Veghel, K., Roosendaal, G., Biesma, D. H., Lafeber, F. P.J.G.

“…Summary Recurrent joint bleeding is the most common manifestation of severe haemophilia resulting in haemophilic arthropathy (HA). Iron plays a central role in…”
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Design of a Prospective Study on Pharmacokinetic-Guided Dosing of Prophylactic Factor Replacement in Hemophilia A and B (OPTI-CLOT TARGET Study) by Goedhart, Tine M H J, Bukkems, Laura H, Coppens, Michiel, Fijnvandraat, Karin J, Schols, Saskia E M, Schutgens, Roger E G, Eikenboom, Jeroen, Heubel-Moenen, Floor C J I, Ypma, Paula F, Nieuwenhuizen, L, Meijer, K, Leebeek, Frank W G, Mathôt, Ron A A, Cnossen, Marjon H

“…In resource-rich countries, almost all severe hemophilia patients receive prophylactic replacement therapy with factor concentrates to prevent spontaneous…”
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Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT: to WiN study by Heijdra, Jessica M, Al Arashi, Wala, de Jager, Nico C B, Cloesmeijer, Michael E, Bukkems, Laura H, Zwaan, Christian M, Leebeek, Frank W G, Mathôt, Ron A A, Cnossen, Marjon H, Cnossen, MH, Leebeek, FWG, Fijnvandraat, K, Mathôt, RAA, Meijer, K, Kruip, MJHA, Polinder, S, Coppens, M, Tamminga, RYJ, Laros-van Gorkom, BAP, Brons, P, Schols, SEM, van der Meer, FJM, Eikenboom, HCJ, Schutgens, REG, Fischer, K, Heubel-Moenen, F, Nieuwenhuizen, L, Ypma, P, Driessens, MHE, Zwaan, CM, van Vliet, I, Collins, PW, Liesner, R, Chowdary, P, Keeling, D, Lock, J, Hazendonk, HCAM, van Moort, I, Preijers, T, Heijdra, JM, de Jager, NCB, Goedhart, MCHJ, Bukkems, LH, Al Arashi, W, Cloesmeijer, ME, Janssen, A

“…IntroductionVon Willebrand disease (VWD) is a bleeding disorder, caused by a deficiency or defect of von Willebrand factor (VWF). In case of medical procedures…”
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Tachyphylaxis and reproducibility of desmopressin response in perioperative persons with nonsevere hemophilia A: implications for clinical practice by Romano, L.G.R., Schütte, L.M., van Hest, R.M., Meijer, K., Laros-van Gorkom, B.A.P., Nieuwenhuizen, L., Eikenboom, J., Heubel-Moenen, F.C.J.I., Uitslager, N., Coppens, M., Fijnvandraat, K., Driessens, M.H.E., Polinder, S., Cnossen, M.H., Leebeek, F.W.G., Mathôt, R.A.A., Kruip, M.J.H.A.

“…Desmopressin is frequently used perioperatively in persons with nonsevere hemophilia A. However, increase in factor (F)VIII:C after desmopressin use is…”
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Successful treatment of aplastic anaemia with cyclosporine during pregnancy by Hermans, B C M, Zanders, M M, van Oostrum, N H M, Kuijper, P H M, Nieuwenhuizen, L

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Antiplasmin, but not amiloride, prevents synovitis and cartilage damage following hemarthrosis in hemophilic mice by Nieuwenhuizen, L., Roosendaal, G., Mastbergen, S. C., Coeleveld, K., Biesma, D. H., Lafeber, F. P. J. G., Schutgens, R. E. G.

“…Summary Background Blood‐induced joint damage is characterized by synovitis and cartilage damage. Recently, we demonstrated that joint bleeding in hemophilic…”
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Paramagnetic self-assembled nanoparticles as supramolecular MRI contrast agents by Besenius, Pol, Heynens, Joeri L M, Straathof, Roel, Nieuwenhuizen, Marko M L, Bomans, Paul H H, Terreno, Enzo, Aime, Silvio, Strijkers, Gustav J, Nicolay, Klaas, Meijer, E W

“…Nanometer-sized materials offer a wide range of applications in biomedical technologies, particularly imaging and diagnostics. Current scaffolds in the…”
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Silencing of protease-activated receptors attenuates synovitis and cartilage damage following a joint bleed in haemophilic mice by Nieuwenhuizen, L., Schutgens, R. E. G., Coeleveld, K., Mastbergen, S. C., Schiffelers, R. M., Roosendaal, G., Biesma, D. H., Lafeber, F. P. J. G.

“…Introduction and aim Joint bleeding results in blood‐induced arthropathy. We investigate whether a joint bleed alters protease‐activated receptor (PAR)…”
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Cooperative Two-Component Self-Assembly of Mono- and Ditopic Monomers by Smulders, Maarten M. J, Nieuwenhuizen, Marko M. L, Grossman, Madeleine, Filot, Ivo A. W, Lee, Cameron C, de Greef, Tom F. A, Schenning, Albertus P. H. J, Palmans, Anja R. A, Meijer, E. W

“…A N-methylated benzene-1,3,5-tricarboxamide (BTA) was synthesized, characterized, and introduced as a monotopic BTA monomer capable of interacting with the…”
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The influence of ethylene glycol chains on the thermodynamics of hydrogen-bonded supramolecular assemblies in apolar solvents by de Greef, Tom F A, Nieuwenhuizen, Marko M L, Stals, Patrick J M, Fitié, Carel F C, Palmans, Anja R A, Sijbesma, Rint P, Meijer, E W

“…Substitution of hydrogen bond directed supramolecular assemblies with ethylene glycol chains leads to a reduction in the association constant in apolar…”
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Stimulation of Naïve Monocytes and PBMCs with Coagulation Proteases Results in Thrombin‐Mediated and PAR‐1‐Dependent Cytokine Release and Cell Proliferation in PBMCs Only by Nieuwenhuizen, L., Falkenburg, W. J. J., Schutgens, R. E. G., Roosendaal, G., Veghel, K., Biesma, D. H., Lafeber, F. P. J. G.

“…Protease‐activated receptors (PARs) are stimulated by proteolytic cleavage of their extracellular domain. Coagulation proteases, such as FVIIa, the binary…”
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