Search Results - "Nieuwenhuis, E ES"

FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis by van Boxtel, R, Gomez-Puerto, C, Mokry, M, Eijkelenboom, A, van der Vos, K E, Nieuwenhuis, E ES, Burgering, B MT, Lam, E W -F, Coffer, P J

“…Transcriptional activity of Forkhead box transcription factor class O (FOXO) proteins can result in a variety of cellular outcomes depending on cell type and…”
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The Value of a Checklist for Child Abuse in Out-of-Hours Primary Care: To Screen or Not to Screen by Schouten, Maartje C M, van Stel, Henk F, Verheij, Theo J M, Houben, Michiel L, Russel, Ingrid M B, Nieuwenhuis, Edward E S, van de Putte, Elise M

“…To assess the diagnostic value of the screening instrument SPUTOVAMO-R2 (checklist, 5 questions) for child abuse at Out-of-hours Primary Care locations (OPC),…”
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Overlap, Common Features, and Essential Differences in Pediatric Granulomatous Inflammatory Bowel Disease by Damen, Gerard M, Krieken, J Han, Hoppenreijs, Esther, Os, Erim, Tolboom, Jules JM, Warris, Adillia, Yntema, Jan‐Bart, Nieuwenhuis, Edward ES, Escher, Johanna C

“…ABSTRACT Overlap in the clinical presentation of pediatric granulomatous inflammatory bowel disease may be substantial, depending on the mode of presentation…”
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Role of the Innate Immune System in the Pathogenesis of Inflammatory Bowel Disease by Lierop, Pieter PE, Samsom, Janneke N, Escher, Johanna C, Nieuwenhuis, Edward ES

“…ABSTRACT Crohn disease and ulcerative colitis are chronic inflammatory diseases of the intestinal tract commonly denoted as inflammatory bowel diseases. It has…”
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Contributions of mucosal immune cells to methotrexate-induced mucositis by de Koning, Barbara AE, van Dieren, Jolanda M, Lindenbergh-Kortleve, Dicky J, van der Sluis, Maria, Matsumoto, Tetsuya, Yamaguchi, Keizo, Einerhand, Alexandra W, Samsom, Janneke N, Pieters, Rob, Nieuwenhuis, Edward ES

“…The use of high doses of the anti-cancer drug methotrexate (MTX) is associated with intestinal damage. As a result, mucosal immune cells become increasingly…”
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Child abuse inventory at emergency rooms: CHAIN-ER rationale and design by Sittig, Judith S, Uiterwaal, Cuno S P M, Moons, Karel G M, Nieuwenhuis, Edward E S, van de Putte, Elise M

“…Child abuse and neglect is an important international health problem with unacceptable levels of morbidity and mortality. Although maltreatment as a cause of…”
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Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ by Farin, Henner F, Karthaus, Wouter R, Kujala, Pekka, Rakhshandehroo, Maryam, Schwank, Gerald, Vries, Robert G J, Kalkhoven, Eric, Nieuwenhuis, Edward E S, Clevers, Hans

“…Paneth cells (PCs) are terminally differentiated, highly specialized secretory cells located at the base of the crypts of Lieberkühn in the small intestine…”
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Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location‐Specific Function by Middendorp, Sabine, Schneeberger, Kerstin, Wiegerinck, Caroline L., Mokry, Michal, Akkerman, Ronald D. L., Wijngaarden, Simone, Clevers, Hans, Nieuwenhuis, Edward E. S.

“…Differentiation and specialization of epithelial cells in the small intestine are regulated in two ways. First, there is differentiation along the crypt‐villus…”
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An extensively hydrolysed casein-based formula for infants with cows' milk protein allergy: tolerance/hypo-allergenicity and growth catch-up by Dupont, Christophe, Hol, Jeroen, Nieuwenhuis, Edward E. S.

“…Children with cows' milk protein allergy (CMPA) are at risk of insufficient length and weight gain, and the nutritional efficacy of hypo-allergenic formulas…”
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Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function by van Loosdregt, Jorg, Fleskens, Veerle, Tiemessen, Machteld M., Mokry, Michal, van Boxtel, Ruben, Meerding, Jenny, Pals, Cornelieke E.G.M., Kurek, Dorota, Baert, Miranda R.M., Delemarre, Eveline M., Gröne, Andrea, Koerkamp, Marianne J.A. Groot, Sijts, Alice J.A.M., Nieuwenhuis, Edward E.S., Maurice, Madelon M., van Es, Johan H., ten Berge, Derk, Holstege, Frank C., Staal, Frank J.T., Zaiss, Dietmar M.W., Prakken, Berent J., Coffer, Paul J.

“…Foxp3 is crucial for both the development and function of regulatory T (Treg) cells; however, the posttranslational mechanisms regulating Foxp3 transcriptional…”
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An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking by Schneeberger, Kerstin, Vogel, Georg F., Teunissen, Hans, van Ommen, Domenique D., Begthel, Harry, Bouazzaoui, Layla El, van Vugt, Anke H. M., Beekman, Jeffrey M., Klumperman, Judith, Müller, Thomas, Janecke, Andreas, Gerner, Patrick, Huber, Lukas A., Hess, Michael W., Clevers, Hans, van Es, Johan H., Nieuwenhuis, Edward E. S., Middendorp, Sabine

“…Microvillus inclusion disease (MVID) is a rare intestinal enteropathy with an onset within a few days to months after birth, resulting in persistent watery…”
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T lymphocyte-dependent and -independent regulation of Cxcl8 expression in zebrafish intestines by Brugman, Sylvia, Witte, Merlijn, Scholman, Rianne C, Klein, Mark R, Boes, Marianne, Nieuwenhuis, Edward E S

“…CXCL8 is a potent neutrophil recruiting chemokine. CXCL8 is produced by several innate immune cells, including neutrophils, macrophages, as well as epithelial…”
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The acquisition of tolerance toward cow's milk through probiotic supplementation: A randomized, controlled trial by Hol, Jeroen, MD, van Leer, Eduard H.G., MD, PhD, Elink Schuurman, Beatrix E.E., MScN, de Ruiter, Lilian F, Samsom, Janneke N., PhD, Hop, Wim, MD, PhD, Neijens, Herman J., MD, PhD, de Jongste, Johan C., MD, PhD, Nieuwenhuis, Edward E.S., MD, PhD

“…Background Cow's milk allergy (CMA) is the most frequently diagnosed food allergy in infancy. In general, patients have a good prognosis because the majority…”
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Extensive Association of Common Disease Variants with Regulatory Sequence by Mokry, Michal, Harakalova, Magdalena, Asselbergs, Folkert W, de Bakker, Paul I W, Nieuwenhuis, Edward E S

“…Overlap between non-coding DNA regulatory sequences and common variant associations can help to identify specific cell and tissue types that are relevant for…”
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Novel approaches: Tissue engineering and stem cells – In vitro modelling of the gut by van Rijn, Jorik M., MSc, Schneeberger, Kerstin, PhD, Wiegerinck, Caroline L., PhD, Nieuwenhuis, Edward E.S., MD, PhD, Middendorp, Sabine, PhD

“…Abstract In many intestinal diseases, the function of the epithelial lining is impaired. In this review, we describe the recent developments of in vitro…”
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T lymphocytes control microbial composition by regulating the abundance of Vibrio in the zebrafish gut by Brugman, Sylvia, Schneeberger, Kerstin, Witte, Merlijn, Klein, Mark R, van den Bogert, Bartholomeus, Boekhorst, Jos, Timmerman, Harro M, Boes, Marianne L, Kleerebezem, Michiel, Nieuwenhuis, Edward ES

“…Dysbiosis of the intestinal microbial community is considered a risk factor for development of chronic intestinal inflammation as well as other diseases such…”
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Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization by Haitjema, Saskia, Meddens, Claartje A, van der Laan, Sander W, Kofink, Daniel, Harakalova, Magdalena, Tragante, Vinicius, Foroughi Asl, Hassan, van Setten, Jessica, Brandt, Maarten M, Bis, Joshua C, O’Donnell, Christopher, Cheng, Caroline, Hoefer, Imo E, Waltenberger, Johannes, Biessen, Erik, Jukema, J Wouter, Doevendans, Pieter A.F.M, Nieuwenhuis, Edward E.S, Erdmann, Jeanette, Björkegren, Johan L.M, Pasterkamp, Gerard, Asselbergs, Folkert W, den Ruijter, Hester M, Mokry, Michal

“…BACKGROUND—As genome-wide association efforts, such as CARDIoGRAM and METASTROKE, are ongoing to reveal susceptibility loci for their underlying…”
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Mucosal control of the intestinal microbial community by Brugman, Sylvia, Nieuwenhuis, Edward E. S.

“…Although the knowledge of the effects of bacterial colonization on the immune system is rapidly expanding, surprisingly little is known about the immunological…”
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Development of lactococcal GEM-based pneumococcal vaccines by Audouy, Sandrine A.L, van Selm, Saskia, van Roosmalen, Maarten L, Post, Eduard, Kanninga, Rolf, Neef, Jolanda, Estevão, Silvia, Nieuwenhuis, Edward E.S, Adrian, Peter V, Leenhouts, Kees, Hermans, Peter W.M

“…Abstract We report the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae , in which three pneumococcal proteins were…”
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Evaluation of suspected child abuse at the ED; implementation of American Academy of Pediatrics guidelines in the Netherlands by Sittig, Judith S., MD, Post, Erica D.M., MD, Russel, Ingrid M.B., MD, van Dijk, Ingrid A.G., MD, Nieuwenhuis, Edward E.S., MD, PhD, van de Putte, Elise M., MD, PhD

“…Abstract Emergency departments (EDs) are important to detect child physical abuse. A structured approach will contribute to an adequate detection of abused…”
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