Search Results - "Niessen, W"

Tackling socioeconomic inequalities and non-communicable diseases in low-income and middle-income countries under the Sustainable Development agenda by Niessen, Louis W, Mohan, Diwakar, Akuoku, Jonathan K, Mirelman, Andrew J, Ahmed, Sayem, Koehlmoos, Tracey P, Trujillo, Antonio, Khan, Jahangir, Peters, David H

“…Five Sustainable Development Goals (SDGs) set targets that relate to the reduction of health inequalities nationally and worldwide. These targets are poverty…”
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Tandem mass spectrometry of small-molecule antiviral drugs: 3. antiviral agents against herpes, influenza and other viral infections by Niessen, W.M.A.

“…For the treatment of various viral infections, antiviral drugs may be used. Liquid chromatography–mass spectrometry (LC–MS) with tandem mass spectrometry…”
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Tandem mass spectrometry of small-molecule antiviral drugs: 1. HIV-related antivirals by Niessen, W.M.A.

“…Antiviral drugs are a class of compounds developed specifically for the treatment of viral infections. In the development and subsequent application of…”
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Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group by Schmaal, L, Veltman, D J, van Erp, T G M, Sämann, P G, Frodl, T, Jahanshad, N, Loehrer, E, Tiemeier, H, Hofman, A, Niessen, W J, Vernooij, M W, Ikram, M A, Wittfeld, K, Grabe, H J, Block, A, Hegenscheid, K, Völzke, H, Hoehn, D, Czisch, M, Lagopoulos, J, Hatton, S N, Hickie, I B, Goya-Maldonado, R, Krämer, B, Gruber, O, Couvy-Duchesne, B, Rentería, M E, Strike, L T, Mills, N T, de Zubicaray, G I, McMahon, K L, Medland, S E, Martin, N G, Gillespie, N A, Wright, M J, Hall, G B, MacQueen, G M, Frey, E M, Carballedo, A, van Velzen, L S, van Tol, M J, van der Wee, N J, Veer, I M, Walter, H, Schnell, K, Schramm, E, Normann, C, Schoepf, D, Konrad, C, Zurowski, B, Nickson, T, McIntosh, A M, Papmeyer, M, Whalley, H C, Sussmann, J E, Godlewska, B R, Cowen, P J, Fischer, F H, Rose, M, Penninx, B W J H, Thompson, P M, Hibar, D P

“…The pattern of structural brain alterations associated with major depressive disorder (MDD) remains unresolved. This is in part due to small sample sizes of…”
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Tandem mass spectrometry of organic nitro and halogen compounds: Competition between losses of molecules and of radicals by Niessen, W.M.A.

“…Fragmentation of protonated and/or deprotonated small-molecule compounds in tandem mass spectrometry after electrospray ionization involves complex processes…”
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Tandem mass spectrometry of small-molecule antiviral drugs: 2. hepatitis-related antivirals by Niessen, W.M.A.

“…Antiviral drugs are a class of compounds developed specifically for the treatment of viral infections. Quantitative analysis of antiviral drugs in biological…”
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Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species by Baglio, Serena Rubina, Rooijers, Koos, Koppers-Lalic, Danijela, Verweij, Frederik J, Pérez Lanzón, M, Zini, Nicoletta, Naaijkens, Benno, Perut, Francesca, Niessen, Hans W M, Baldini, Nicola, Pegtel, D Michiel

“…Administration of mesenchymal stem cells (MSCs) represents a promising treatment option for patients suffering from immunological and degenerative disorders…”
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Interpretation of tandem mass spectra of antiepileptic drugs using accurate-m/z data and m/z-shifts with stable-isotope labeled analogues by Niessen, W.M.A.

“…Anticonvulsant or antiepileptic drugs (AEDs) show a great structural diversity. Often, therapeutic drug monitoring (TDM) based on liquid…”
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Cancer drug addiction is relayed by an ERK2-dependent phenotype switch by Kong, Xiangjun, Kuilman, Thomas, Shahrabi, Aida, Boshuizen, Julia, Kemper, Kristel, Song, Ji-Ying, Niessen, Hans W. M., Rozeman, Elisa A., Geukes Foppen, Marnix H., Blank, Christian U., Peeper, Daniel S.

“…The identification of an ERK2–JUNB–FRA1 signalling pathway that drives addiction to therapeutic drugs in cancer cells, and an ERK2-dependent phenotype switch…”
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Cerebral microbleeds are associated with worse cognitive function: The Rotterdam Scan Study by POELS, M. M. F, IKRAM, M. A, VAN DER LUGT, A, HOFMAN, A, NIESSEN, W. J, KRESTIN, G. P, BRETELER, M. M. B, VERNOOIJ, M. W

“…Cerebral microbleeds are frequently found in the general elderly population and may reflect underlying vascular disease, but their role in cognitive function…”
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Matrix effects in quantitative pesticide analysis using liquid chromatography-mass spectrometry by Niessen, W.M.A., Manini, P., Andreoli, R.

“…Combined liquid chromatography–mass spectrometry using electrospray or atmospheric‐pressure chemical ionization has become an important tool in the…”
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Prevalence and risk factors of cerebral microbleeds : The Rotterdam Scan Study by VERNOOIJ, M. W, VAN DER LUGT, A, IKRAM, M. A, WIELOPOLSKI, P. A, NIESSEN, W. J, HOFMAN, A, KRESTIN, G. P, BRETELER, M. M. B

“…Cerebral microbleeds are focal deposits of hemosiderin that can be visualized with MRI. Little is known on their prevalence in the general population and on…”
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Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group by Schmaal, L, Hibar, D P, Sämann, P G, Hall, G B, Baune, B T, Jahanshad, N, Cheung, J W, van Erp, T G M, Bos, D, Ikram, M A, Vernooij, M W, Niessen, W J, Tiemeier, H, Hofman, A, Wittfeld, K, Grabe, H J, Janowitz, D, Bülow, R, Selonke, M, Völzke, H, Grotegerd, D, Dannlowski, U, Arolt, V, Opel, N, Heindel, W, Kugel, H, Hoehn, D, Czisch, M, Couvy-Duchesne, B, Rentería, M E, Strike, L T, Wright, M J, Mills, N T, de Zubicaray, G I, McMahon, K L, Medland, S E, Martin, N G, Gillespie, N A, Goya-Maldonado, R, Gruber, O, Krämer, B, Hatton, S N, Lagopoulos, J, Hickie, I B, Frodl, T, Carballedo, A, Frey, E M, van Velzen, L S, Penninx, B W J H, van Tol, M-J, van der Wee, N J, Davey, C G, Harrison, B J, Mwangi, B, Cao, B, Soares, J C, Veer, I M, Walter, H, Schoepf, D, Zurowski, B, Konrad, C, Schramm, E, Normann, C, Schnell, K, Sacchet, M D, Gotlib, I H, MacQueen, G M, Godlewska, B R, Nickson, T, McIntosh, A M, Papmeyer, M, Whalley, H C, Hall, J, Sussmann, J E, Li, M, Walter, M, Aftanas, L, Brack, I, Bokhan, N A, Thompson, P M, Veltman, D J

“…The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades…”
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Fragmentation of toxicologically relevant drugs in negative-ion liquid chromatography-tandem mass spectrometry by Niessen, W.M.A.

“…Negative‐ion LC–MS analysis of drugs is applied far less frequently than positive‐ion LC–MS. Data on the interpretation of negative‐ion MS–MS spectra are even…”
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Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry by Niessen, W.M.A.

“…The identification of drugs and related compounds by LC–MS–MS is an important analytical challenge in several application areas, including clinical and…”
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Amino acid analysis using chromatography–mass spectrometry: An inter platform comparison study by Krumpochova, P., Bruyneel, B., Molenaar, D., Koukou, A., Wuhrer, M., Niessen, W.M.A., Giera, M.

“…[Display omitted] •Comparison of three state-of-the art analysis platforms for amino acid analysis.•Detailed comparison of analytical figures of…”
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Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir by van der Laan, Anja M, Ter Horst, Ellis N, Delewi, Ronak, Begieneman, Mark P V, Krijnen, Paul A J, Hirsch, Alexander, Lavaei, Mehrdad, Nahrendorf, Matthias, Horrevoets, Anton J, Niessen, Hans W M, Piek, Jan J

“…Monocytes are critical mediators of healing following acute myocardial infarction (AMI), making them an interesting target to improve myocardial repair. The…”
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Interpretation of MS–MS spectra of small-molecule signal transduction inhibitors using accurate-m/z data and m/z-shifts with stable-isotope-labeled analogues and metabolites by Niessen, W.M.A., Rosing, H., Beijnen, J.H.

“…Signal transduction inhibitors (STIs), especially tyrosine kinase inhibitors, are being used to treat diseases in which deregulation of the protein kinase…”
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Quantitative Comparison of Spot Detection Methods in Fluorescence Microscopy by Smal, I., Loog, M., Niessen, W., Meijering, E.

“…Quantitative analysis of biological image data generally involves the detection of many subresolution spots. Especially in live cell imaging, for which…”
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