Search Results - "Niesnerová, Anezka"
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Dual spatially resolved transcriptomics for human host-pathogen colocalization studies in FFPE tissue sections
Published in Genome Biology (19-10-2023)“…Technologies to study localized host-pathogen interactions are urgently needed. Here, we present a spatial transcriptomics approach to simultaneously capture…”
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High resolution spatial profiling of kidney injury and repair using RNA hybridization-based in situ sequencing
Published in Nature communications (15-02-2024)“…Emerging spatially resolved transcriptomics technologies allow for the measurement of gene expression in situ at cellular resolution. We apply direct RNA…”
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Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens
Published in Frontiers in microbiology (31-07-2019)“…Syphilis, caused by subsp. (TPA), remains an important public health problem with an increasing worldwide prevalence. Despite recent advances in cultivation,…”
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APOE genotype dictates lipidomic signatures in primary human hepatocytes
Published in Journal of lipid research (01-02-2024)“…Apolipoprotein E (APOE) genetic variants are most notably known for their divergent impact on the risk of developing Alzheimer’s disease. While APOE genotype…”
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APOE genotype‐specific lipidomic signatures in primary human hepatocytes
Published in Alzheimer's & dementia (01-12-2023)“…Background Apolipoprotein E (APOE) is primarily responsible for cholesterol homeostasis in the periphery and in the brain through independently regulated…”
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