Search Results - "Nies, Vera"

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease by Liu, Weilin, Struik, Dicky, Nies, Vera J. M., Jurdzinski, Angelika, Harkema, Liesbeth, de Bruin, Alain, Verkade, Henkjan J., Downes, Michael, Evans, Ronald M., van Zutphen, Tim, Jonker, Johan W.

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder and is strongly associated with obesity and type 2 diabetes. Currently,…”
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Autocrine FGF1 signaling promotes glucose uptake in adipocytes by Nies, Vera J M, Struik, Dicky, Liu, Sihao, Liu, Weilin, Kruit, Janine K, Downes, Michael, van Zutphen, Tim, Verkade, Henkjan J, Evans, Ronald M, Jonker, Johan W

“…Fibroblast growth factor 1 (FGF1) is an autocrine growth factor released from adipose tissue during over-nutrition or fasting to feeding transition. While…”
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Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets by van der Meulen, Talitha, Mawla, Alex M., DiGruccio, Michael R., Adams, Michael W., Nies, Vera, Dólleman, Sophie, Liu, Siming, Ackermann, Amanda M., Cáceres, Elena, Hunter, Anna E., Kaestner, Klaus H., Donaldson, Cynthia J., Huising, Mark O.

“…Postnatal maintenance or regeneration of pancreatic beta cells is considered to occur exclusively via the replication of existing beta cells, but clinically…”
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Fibroblast Growth Factor Signaling in Metabolic Regulation by Nies, Vera J M, Sancar, Gencer, Liu, Weilin, van Zutphen, Tim, Struik, Dicky, Yu, Ruth T, Atkins, Annette R, Evans, Ronald M, Jonker, Johan W, Downes, Michael Robert

“…The prevalence of obesity is a growing health problem. Obesity is strongly associated with several comorbidities, such as non-alcoholic fatty liver disease,…”
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Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study by Muurling, Marijn, de Boer, Casper, Kozak, Rouba, Religa, Dorota, Koychev, Ivan, Verheij, Herman, Nies, Vera J M, Duyndam, Alexander, Sood, Meemansa, Fröhlich, Holger, Hannesdottir, Kristin, Erdemli, Gul, Lucivero, Federica, Lancaster, Claire, Hinds, Chris, Stravopoulos, Thanos G, Nikolopoulos, Spiros, Kompatsiaris, Ioannis, Manyakov, Nikolay V, Owens, Andrew P, Narayan, Vaibhav A, Aarsland, Dag, Visser, Pieter Jelle

“…Functional decline in Alzheimer's disease (AD) is typically measured using single-time point subjective rating scales, which rely on direct observation or…”
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Hyperglycemia Induces Bioenergetic Changes in Adipose-Derived Stromal Cells While Their Pericytic Function Is Retained by Hajmousa, Ghazaleh, Elorza, Alvaro A, Nies, Vera J M, Jensen, Erik L, Nagy, Ruxandra A, Harmsen, Martin C

“…Diabetic retinopathy (DR) is a hyperglycemia (HG)-mediated microvascular complication. In DR, the loss of pericytes and subsequently endothelial cells leads to…”
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Digital endpoints in clinical trials of Alzheimer's disease and other neurodegenerative diseases: challenges and opportunities by Brem, Anna-Katharine, Kuruppu, Sajini, de Boer, Casper, Muurling, Marijn, Diaz-Ponce, Ana, Gove, Dianne, Curcic, Jelena, Pilotto, Andrea, Ng, Wan-Fai, Cummins, Nicholas, Malzbender, Kristina, Nies, Vera J M, Erdemli, Gul, Graeber, Johanna, Narayan, Vaibhav A, Rochester, Lynn, Maetzler, Walter, Aarsland, Dag

“…Alzheimer's disease (AD) and other neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's disease (HD) are associated with progressive…”
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Regulatory considerations for developing remote measurement technologies for Alzheimer’s disease research by Erdemli, Gül, Grammatikopoulou, Margarita, Wagner, Bertil, Vairavan, Srinivasan, Curcic, Jelena, Aarsland, Dag, Wittenberg, Gayle, Nikolopoulos, Spiros, Muurling, Marijn, Froehlich, Holger, de Boer, Casper, Shanbhag, Niraj M., Nies, Vera J. M., Coello, Neva, Gove, Dianne, Diaz, Ana, Foy, Suzanne, Dartee, Wim, Brem, Anna-Katharine

“…The Remote Assessment of Disease and Relapse – Alzheimer’s Disease (RADAR-AD) consortium evaluated remote measurement technologies (RMTs) for assessing…”
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GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis by Qin, Jing, Sikkema, Arend H, van der Bij, Kristine, de Jonge, Jenny C, Klappe, Karin, Nies, Vera, Jonker, Johan W, Kok, Jan Willem, Hoekstra, Dick, Baron, Wia

“…Remyelination failure by oligodendrocytes contributes to the functional impairment that characterizes the demyelinating disease multiple sclerosis (MS). Since…”
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An app to measure functional decline in managing finances in Alzheimer’s disease: Preliminary results of the RADAR‐AD study by Stavropoulos, Thanos G., Mpaltadoros, Lampros, Lazarou, Ioulietta, Grammatikopoulou, Margarita, Muurling, Marijn, de Boer, Casper, Curcic, Jelena, Kouzak, Rouba, Verheij, Herman, Nies, Vera J.M., Durudas, Andre, Hannesdottir, Kristin, Hinds, Chris, Daskalova, Yoanna, Owens, Andrew P., Wu, Yuhao, Erdemli, Gul, Stolk, Pieter, Lucivero, Federica, Narayan, Vaibhav A., Aarsland, Dag, Nikolopoulos, Spiros, Tsolaki, Magda, Visser, Pieter Jelle, Kompatsiaris, Ioannis

“…Background The on‐going ‘Remote Assessment of Disease and Relapse – Alzheimer’s Disease’ (RADAR‐AD, https://www.radar‐ad.org/) international study uses remote…”
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Gait characteristics in preclinical Alzheimer’s disease: Preliminary results of the RADAR‐AD study by de Boer, Casper, Muurling, Marijn, Curcic, Jelena, Kouzak, Rouba, Verheij, Herman, Nies, Vera J.M., Durudas, Andre, Hannesdottir, Kristin, Hinds, Chris, Stavropoulos, Thanos G., Daskalova, Yoanna, Owens, Andrew P., Wu, Yuhao, Erdemli, Gul, Stolk, Pieter, Lucivero, Federica, Narayan, Vaibhav A., Aarsland, Dag, Visser, Pieter Jelle

“…Background The Remote Assessment of Disease and Relapse – Alzheimer’s Disease (RADAR‐AD) study is assessing functional decline in Alzheimer’s Disease (AD)…”
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Augmented reality to detect subtle alterations in the early stages of Alzheimer’s disease: Preliminary results of the RADAR‐AD study by Muurling, Marijn, de Boer, Casper, Bügler, Maximilian, Harms, Robbert, Tarnanas, Ioannis, Kouzak, Rouba, Verheij, Herman, Nies, Vera J.M., Daskalova, Yoanna, Stolk, Pieter, Durudas, Andre, Curcic, Jelena, Hannesdottir, Kristin, Erdemli, Gul, Hinds, Chris, Wu, Yuhao, Lucivero, Federica, Stavropoulos, Thanos G., Owens, Andrew P., Narayan, Vaibhav A., Aarsland, Dag, Visser, Pieter Jelle

“…Background The ‘Remote Assessment of Disease and Relapse – Alzheimer’s Disease’ (RADAR‐AD) study is assessing functional decline in Alzheimer’s disease (AD)…”
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IMI European Lead Factory — democratizing access to high-throughput screening by Jones, Philip S., Boucharens, Sylviane, McElroy, Stuart P., Morrison, Angus, Honarnejad, Saman, van Boeckel, Stan, van den Hurk, Helma, Basting, Daniel, Hüser, Jörg, Jaroch, Stefan, Ottow, Eckhard, Benningshof, Jorg, Folmer, Rutger H. A., Leemhuis, Frank, Kramer-Verhulst, Patricia M., Nies, Vera J. M., Orrling, Kristina M., Rijnders, Ton, Pfander, Claudia, Engkvist, Ola, Pairaudeau, Garry, Simpson, Peter B., Ortholand, Jean-Yves, Roche, Didier, Dömling, Alexander, Kühnert, Sven M., Roevens, Peter W. M., van Vlijmen, Herman, van Wanrooij, Eva J. A., Verbruggen, Christophe, Nussbaumer, Peter, Ovaa, Huib, van der Stelt, Mario, Simonsen, Klaus Baek, Tagmose, Lena, Waldmann, Herbert, Duffy, James, Finsinger, Dirk, Jurzak, Mirek, Burgess-Brown, Nicola A., Lee, Wen H., Rutjes, Floris P. J. T., Haag, Hubert, Kallus, Christopher, Mors, Hartmut, Dorval, Thierry, Lesur, Brigitte, Ramon Olayo, Fernando, Hamza, Daniel, Jones, Geraint, Pearce, Christopher, Piechot, Alexander, Tzalis, Dimitrios, Clausen, Mads H., Davis, Jeremy, Derouane, Daphné, Vermeiren, Céline, Kaiser, Markus, Stockman, Robert A., Barrault, Denise V., Pannifer, Andrew D., Swedlow, Jason R., Nelson, Adam S., Orru, Romano V. A., Ruijter, Eelco, van Helden, Steven P., Li, Volkhart M., Vries, Ton, de Vlieger, Jon S. B.

“…The European Lead Factory combines assets and experience from major pharma with innovation and agility of academia and SMEs in a collaborative platform to…”
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