Search Results - "Niermann, Kenneth J."

Targeting the Mechanisms of Resistance to Chemotherapy and Radiotherapy with the Cancer Stem Cell Hypothesis by Morrison, Ryan, Schleicher, Stephen M., Sun, Yunguang, Niermann, Kenneth J., Kim, Sungjune, Spratt, Daniel E., Chung, Christine H., Lu, Bo

“…Despite advances in treatment, cancer remains the 2nd most common cause of death in the United States. Poor cure rates may result from the ability of cancer to…”
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Integration of quantitative DCE-MRI and ADC mapping to monitor treatment response in human breast cancer: initial results by Yankeelov, Thomas E, Lepage, Martin, Chakravarthy, Anuradha, Broome, Elizabeth E, Niermann, Kenneth J, Kelley, Mark C, Meszoely, Ingrid, Mayer, Ingrid A, Herman, Cheryl R, McManus, Kevin, Price, Ronald R, Gore, John C

“…Abstract Purpose The objective of this study was to assess changes in the water apparent diffusion coefficient (ADC) and in pharmacokinetic parameters obtained…”
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A Randomized Feasibility Trial to Evaluate Use of the Jaw Dynasplint to Prevent Trismus in Patients With Head and Neck Cancer Receiving Primary or Adjuvant Radiation-Based Therapy by Zatarain, Lauren A., Smith, Derek K., Deng, Jie, Gilbert, Jill, Dietrich, Mary S., Niermann, Kenneth J., Ridner, Sheila H., Murphy, Barbara A.

“…Objective: This study was designed to assess the feasibility of using the Jaw Dynasplint System as an adjunct to conventional stretching exercises as a…”
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Combining registration and active shape models for the automatic segmentation of the lymph node regions in head and neck CT images by Chen, Antong, Deeley, Matthew A., Niermann, Kenneth J., Moretti, Luigi, Dawant, Benoit M.

“…Purpose: Intensity-modulated radiation therapy (IMRT) is the state of the art technique for head and neck cancer treatment. It requires precise delineation of…”
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Evaluation of CT Changes in the Head and Neck After Cancer Treatment: Development of a Measurement Tool by Aulino, Joseph M, Wulff-Burchfield, Elizabeth M, Dietrich, Mary S, Ridner, Sheila H, Niermann, Kenneth J, Deng, Jie, Rhoten, Bethany A, Doersam, Jennifer K, Jarrett, Lee Ann, Mannion, Kyle, Murphy, Barbara A

“…The late effect continuum of lymphedema and fibrosis (LEF) affects more than 70% of patients after treatment for head and neck cancer (HNC). LEF is associated…”
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Enzastaurin (LY317615), a Protein Kinase C Beta Selective Inhibitor, Enhances Antiangiogenic Effect of Radiation by Willey, Christopher D., M.D., Ph.D, Xiao, Dakai, Ph.D, Tu, Tianxiang, M.D, Kim, Kwang Woon, Ph.D, Moretti, Luigi, M.D, Niermann, Kenneth J., M.D, Tawtawy, Mohammed N., Ph.D, Quarles, Chad C., Ph.D, Lu, Bo, M.D., Ph.D

“…Purpose Angiogenesis has generated interest in oncology because of its important role in cancer growth and progression, particularly when combined with…”
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Refinement and Validation of the Head and Neck Lymphedema and Fibrosis Symptom Inventory by Deng, Jie, Dietrich, Mary S., Niermann, Kenneth J., Sinard, Robert J., Cmelak, Anthony J., Ridner, Sheila H., Gilbert, Jill, Murphy, Barbara A.

“…Lymphedema and fibrosis (LEF) are common yet overlooked late effects of head and neck cancer and its therapy. Lack of reliable and valid measures of head and…”
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Feasibility and Tolerability of Adjuvant Capecitabine-Based Chemoradiation in Patients With Breast Cancer and Residual Disease After Neoadjuvant Chemotherapy: A Prospective Clinical Trial by Balbach, Meridith L., Sherry, Alexander D., Rexer, Brent N., Abramson, Vandana G., Niermann, Kenneth J., Johnson, Corbin R., Park, Ben Ho, Mayer, Ingrid A., Chakravarthy, A. Bapsi

“…Addition of adjuvant capecitabine improves overall survival for patients with breast cancer lacking pathologic complete response to standard-of-care…”
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Differential Efficacy of Combined Therapy With Radiation and AEE788 in High and Low EGFR-Expressing Androgen-Independent Prostate Tumor Models by Huamani, Jessica, M.S, Willey, Christopher, M.D., Ph.D, Thotala, Dinesh, Ph.D, Niermann, Kenneth J., M.D, Reyzer, Michelle, Ph.D, Leavitt, Lauren, B.S, Jones, Cameron, B.S, Fleishcher, Arthur, M.D, Caprioli, Richard, Ph.D, Hallahan, Dennis E., M.D, Kim, Dong Wook Nathan, M.D., Ph.D

“…Purpose To determine the efficacy of combining radiation (XRT) with a dual epidermal growth factor receptor (EGFR)/vascular endothelial growth factor receptor…”
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Validity Testing of the Head and Neck Lymphedema and Fibrosis Symptom Inventory by Deng, Jie, Murphy, Barbara A, Niermann, Kenneth J, Sinard, Robert J, Cmelak, Anthony J, Rohde, Sarah L, Ridner, Sheila H, Dietrich, Mary S

“…Lack of reliable and valid tools significantly impacts early identification and timely treatment of lymphedema and fibrosis (LEF) in the head and neck cancer…”
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Vanderbilt head and neck symptom survey, version 2.0: Clinical and research utility for identification of symptom clusters and changes in symptoms over time by Ridner, Sheila H., Rhoten, Bethany A., Niermann, Kenneth J., Murphy, Barbara A., Dietrich, Mary S.

“…•VHNSS 2.0 is a reliable and valid measure of acute and late toxicities in patients treated for HNC.•VHNSS 2.0 is useful to screen, evaluate treatments, and…”
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The controversial abscopal effect by Kaminski, Joseph M., Shinohara, Eric, Summers, James Bradley, Niermann, Kenneth J., Morimoto, Allan, Brousal, Jeffrey

“…The abscopal effect is potentially important for tumor control and is mediated through cytokines and/or the immune system, mainly cell-mediated immunity. It…”
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Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer by Cao, Carolyn, Shinohara, Eric T, Niermann, Kenneth J, Donnelly, Edwin F, Chen, Xinping, Hallahan, Dennis E, Lu, Bo

“…Murine double minute 2 (MDM2) inhibits p53-mediated functions, which are essential for therapies using DNA-damaging agents. The purpose of this study was to…”
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Enhanced Radiosensitivity of Androgen-Resistant Prostate Cancer: AZD1152-Mediated Aurora Kinase B Inhibition by Niermann, Kenneth J, Moretti, Luigi, Giacalone, Nicholas J, Sun, Yunguang, Schleicher, Stephen M, Kopsombut, Prapaporn, Mitchell, Lauren R, Kim, Kwang Woon, Lu, Bo

“…Aurora kinase B (AURKB) is critical to the process of mitosis, aiding in chromosome condensation by phosphorylating histone H3. We investigated the effects of…”
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Measuring tumor perfusion in control and treated murine tumors: correlation of microbubble contrast-enhanced sonography to dynamic contrast-enhanced magnetic resonance imaging and fluorodeoxyglucose positron emission tomography by Niermann, Kenneth J, Fleischer, Arthur C, Huamani, Jessica, Yankeelov, Thomas E, Kim, Dong W, Wilson, Wendy D, Hallahan, Dennis E

“…The purpose of this study was to evaluate the ability of dynamic microbubble contrast-enhanced sonography (MCES), in comparison with dynamic contrast-enhanced…”
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Sonographic assessment of tumor response: from in vivo models to clinical applications by Hwang, Misun, Niermann, Kenneth J, Lyshchik, Andrej, Fleischer, Arthur C

“…The advent of antiangiogenic drugs in cancer therapy necessitates an imaging modality that can longitudinally assess posttreatment changes in tumor…”
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Noninvasive Assessment of Tumor Vasculature Response to Radiation-Mediated, Vasculature-Targeted Therapy Using Quantified Power Doppler Sonography: Implications for Improvement of Therapy Schedules by Kim, Dong Wook Nathan, Huamani, Jessica, Niermann, Kenneth J, Lee, Haakil, Geng, Ling, Leavitt, Lauren L, Baheza, Richard A, Jones, Cameron C, Tumkur, Shiv, Yankeelov, Thomas E, Fleischer, Arthur C, Hallahan, Dennis E

“…Stereotactic radiotherapy (ablative radiation) is a modality that holds considerable promise for effective treatment of intracranial and extracranial…”
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Correlation Between Estimates of Tumor Perfusion From Microbubble Contrast-Enhanced Sonography and Dynamic Contrast-Enhanced Magnetic Resonance Imaging by Yankeelov, Thomas E, Niermann, Kenneth J, Huamani, Jessica, Kim, Dong W, Quarles, Christopher C, Fleischer, Arthur C, Hallahan, Dennis E, Price, Ronald R, Gore, John C

“…Objective. We compared measurements of tumor perfusion from microbub‐ble contrast‐enhanced sonography (MCES) and dynamic contrast‐enhanced magnetic resonance…”
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Sonographic Depiction of Microvessel Perfusion: Principles and Potential by Fleischer, Arthur C, Niermann, Kenneth J, Donnelly, Edwin F, Yankeelov, Thomas E, Canniff, Kathryn M, Hallahan, Dennis E, Rothenberg, Mace E

“…To provide an overview of the technical aspects and potential clinical applications of microvessel perfusion as depicted by microbubble-enhanced sonography…”
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Sonographic depiction of changes of tumor vascularity in response to various therapies by Niermann, Kenneth J, Fleischer, Arthur C, Donnelly, Edwin F, Schueneman, Aaron J, Geng, Ling, Hallahan, Dennis E

“…To evaluate the diagnostic accuracy of power Doppler sonography for the depiction of changes in tumor vascularity with various therapeutic regimens. Tumor…”
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