Search Results - "Nienhuis, Robert"
-
1
Localized Loss of Hypocretin (Orexin) Cells in Narcolepsy Without Cataplexy
Published in Sleep (New York, N.Y.) (01-08-2009)“…Narcolepsy with cataplexy is characterized by a loss of approximately 90% of hypocretin (Hcrt) neurons. However, more than a quarter of narcoleptics do not…”
Get full text
Journal Article -
2
Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy
Published in The Journal of neuroscience (27-04-2011)“…Hypocretin receptor-2 (Hcrt-r2)-mutated dogs exhibit all the major symptoms of human narcolepsy and respond to drugs that increase or decrease cataplexy as do…”
Get full text
Journal Article -
3
Cumulated Ambulation Score to evaluate mobility is feasible in geriatric patients and in patients with hip fracture
Published in Danish medical journal (01-07-2012)“…Regaining basic mobility independence is considered important for elderly hospitalised patients. The Cumulated Ambulation Score (CAS) is a valid tool for…”
Get full text
Journal Article -
4
Pattern of Hypocretin (Orexin) Soma and Axon Loss, and Gliosis, in Human Narcolepsy
Published in Brain pathology (Zurich, Switzerland) (01-07-2003)“…Human narcolepsy is correlated with a greatly reduced number of hypocretin (orexin) containing neurons and axons, and an elevated level of hypothalamic…”
Get full text
Journal Article -
5
Sleep deprivation decreases superoxide dismutase activity in rat hippocampus and brainstem
Published in Neuroreport (07-08-2002)Get full text
Journal Article -
6
Neuronal Activity in Narcolepsy: Identification of Cataplexy-Related Cells in the Medial Medulla
Published in Science (American Association for the Advancement of Science) (31-05-1991)“…Narcolepsy is a neurological disorder characterized by sleepiness and episodes of cataplexy. Cataplexy is an abrupt loss of muscle tone, most often triggered…”
Get full text
Journal Article -
7
Rapid eye movement sleep deprivation contributes to reduction of neurogenesis in the hippocampal dentate gyrus of the adult rat
Published in Sleep (New York, N.Y.) (01-02-2008)“…The dentate gyrus (DG) of the adult hippocampus contains progenitor cells, which have potential to differentiate into neurons. Previously we reported that 96…”
Get full text
Journal Article -
8
Reduced Number of Hypocretin Neurons in Human Narcolepsy
Published in Neuron (Cambridge, Mass.) (01-09-2000)“…Murine and canine narcolepsy can be caused by mutations of the hypocretin (Hcrt) (orexin) precursor or Hcrt receptor genes. In contrast to these animal models,…”
Get full text
Journal Article -
9
Sleep deprivation decreases superoxide dismutase activity in rat hippocampus and brainstem
Published in Neuroreport (07-08-2002)“…Sleep deprivation by the disk-over-water technique results in a predictable syndrome of physiological changes in rats. It has been proposed that reactive…”
Get full text
Journal Article -
10
A randomized controlled trial of the effect of supervised progressive cross-continuum strength training and protein supplementation in older medical patients: the STAND-Cph trial
Published in Current controlled trials in cardiovascular medicine (28-11-2019)“…During hospitalization, older adults (+ 65 years) are inactive, which puts them at risk of functional decline and loss of independence. Systematic strength…”
Get full text
Journal Article -
11
A preliminary examination of astrocyte morphology across multiple human forebrain nuclei
Published in The FASEB journal (01-03-2008)“…Abstract only Multiple physiological roles for astrocytes have emerged over the last two decades, though little attention has focused on astrocyte morphology…”
Get full text
Journal Article -
12
-
13
Altered distribution of cholinergic cells in the narcoleptic dog
Published in Neuroreport (31-07-1995)“…Narcolepsy is characterized by excessive sleepiness and episodes of cataplexy brought on by emotional excitation. Cataplexy and sleep paralysis have been…”
Get more information
Journal Article -
14
Ontogeny of feline temporal lobe epilepsy, II: Stability of spontaneous sleep epilepsy in amygdala-kindled kittens
Published in Epilepsia (Copenhagen) (01-09-1992)“…We previously described a model of spontaneous "sleep epilepsy" in kindled kittens with temporal lobe epilepsy (TLE). We now describe the postkindling course…”
Get more information
Journal Article -
15
Factors influencing faculty retention: A study of job satisfaction and the role of the department chairperson as they relate to faculty members' decisions to remain at Michigan State University
Published 01-01-1992“…Several recent publications have drawn attention to the projected demand for new faculty by the beginning of the next century. The large cohort of faculty…”
Get full text
Dissertation -
16
-
17
Changes in unit responses to tones after food reinforcement in the auditory pathway of the rat: intertrial arousal
Published in Experimental neurology (01-04-1978)Get more information
Journal Article -
18
Patterns of conditioned unit responses in the auditory system of the rat
Published in Experimental neurology (01-04-1978)Get more information
Journal Article -
19
Discharge pattern of reticular formation unit pairs in waking and REM sleep
Published in Experimental neurology (01-12-1981)Get more information
Journal Article