Search Results - "Nieminen, L"

Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in Human carcinoma cells by AHMAD, N, FEYES, D. K, NIEMINEN, A.-L, AGARWAL, R, MUKHTAR, H

“…The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor models. Epidemiologic studies have also suggested that…”
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Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species by Nieminen, A L, Byrne, A M, Herman, B, Lemasters, J J

“…Tert-butyl hydroperoxide (t-BuOOH) induces the mitochondrial permeability transition (MPT) in hepatocytes, leading to cell death. Using confocal microscopy, we…”
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SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus by Viiri, K. M., Korkeamäki, H., Kukkonen, M. K., Nieminen, L. K., Lindfors, K., Peterson, P., Mäki, M., Kainulainen, H., Lohi, O.

“…Histone acetylation plays a key role in the regulation of gene expression. The chromatin structure and accessibility of genes to transcription factors is…”
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Elevated nutrient concentrations in headwaters affected by drained peatland by Marttila, Hannu, Karjalainen, Satu-Maaria, Kuoppala, Minna, Nieminen, Mika L., Ronkanen, Anna-Kaisa, Kløve, Bjørn, Hellsten, Seppo

“…Nutrient export from drained peatland has significant impacts on aquatic environments in Nordic catchments. Spatial information on variations in nutrient…”
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Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons : Evidence of the mitochondrial permeability transition by NIEMINEN, A.-L, PETRIE, T. G, LEMASTERS, J. J, SELMAN, W. R

“…N-Methyl-D-aspartate causes a rapid increase in intracellular Ca2+ leading to collapse of the mitochondrial membrane potential and eventually cell death in…”
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Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes by Dawson, T L, Gores, G J, Nieminen, A L, Herman, B, Lemasters, J J

“…Cell killing, oxygen consumption, and hydroperoxide formation were determined in rat hepatocytes after glycolytic and respiratory inhibition. These conditions…”
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Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls by Nieminen, L.R.G., Makino, K.K., Mehta, N., Virkkunen, M., Kim, H.Y., Hibbeln, J.R.

“…Deficiency in the long-chain ω-3 fatty acid, docosahexaenoic acid (DHA) has been associated with increased corticotropin releasing hormone and may contribute…”
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Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine by Imberti, R, Nieminen, A L, Herman, B, Lemasters, J J

“…In isolated mitochondria, t-butylhydroperoxide (t-BuOOH) and other pro-oxidants cause a permeability transition characterized by increased permeability to…”
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Neuropeptide FF and modulation of pain by Panula, Pertti, Kalso, Eija, Nieminen, Maija-Liisa, Kontinen, Vesa K, Brandt, Annika, Pertovaara, Antti

“…Neuropeptide FF (NPFF) and the related longer peptide neuropeptide AF (NPAF) derive from a single gene in several mammalian species. The gene product is…”
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ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition by Nieminen, A L, Saylor, A K, Herman, B, Lemasters, J J

“…The importance of ATP depletion and mitochondrial depolarization in the toxicity of cyanide, oligomycin, and carbonyl cyanide m-cholorophenylhydrazone (CCCP),…”
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Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide by Nieminen, A L, Saylor, A K, Tesfai, S A, Herman, B, Lemasters, J J

“…We have developed a novel method for monitoring the mitochondrial permeability transition in single intact hepatocytes during injury with t-butylhydroperoxide…”
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Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert‐butylhydroperoxide in rat hepatocytes by Byrne, Aaron M., Lemasters, John J., Nieminen, Anna‐Liisa

“…Previously, we showed that the oxidant chemical,tert‐butylhydroperoxide (t‐BuOOH), induces a mitochondrial permeability transition (MPT) in intact hepatocytes,…”
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Dissipation of Potassium and Proton Gradients Inhibits Mitochondrial Hyperpolarization and Cytochrome c Release during Neural Apoptosis by Poppe, Monika, Reimertz, Claus, Du{beta}mann, Heiko, Krohn, Aaron J, Luetjens, C. Marc, Bockelmann, Doris, Nieminen, Anna-Liisa, Kogel, Donat, Prehn, Jochen H. M

“…Exposure of rat hippocampal neurons or human D283 medulloblastoma cells to the apoptosis-inducing kinase inhibitor staurosporine induced rapid cytochrome c…”
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Intracellular pH during chemical hypoxia in cultured rat hepatocytes: protection by intracellular acidosis against the onset of cell death by GORES, G. J, NIEMINEN, A.-L, WRAY, B. E, HERMAN, B, LEMASTERS, J. J

“…The relationships between extracellular pH (pHo), intracellular pH (pHi), and loss of cell viability were evaluated in cultured rat hepatocytes after ATP…”
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Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes by Gores, G J, Flarsheim, C E, Dawson, T L, Nieminen, A L, Herman, B, Lemasters, J J

“…In rat hepatocytes, we examined the relationship between cell volume, bleb formation, and loss of cell viability during chemical hypoxia with KCN plus…”
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Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization by Lam, M, Oleinick, N L, Nieminen, A L

“…Photodynamic therapy (PDT), a novel and promising cancer treatment that employs a combination of a photosensitizing chemical and visible light, induces…”
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606P Regional lymph nodes (N+ vs N0) in metastatic colorectal cancer by Osterlund, E., Isoniemi, H., Sorbye, H., Pfeiffer, P., Nunes, L., Halonen, P., Uutela, A., Salminen, T., Algars, A., Ristamaki, R., Kallio, R., Lamminmäki, A., Ristimäki, A., Nieminen, L., Sundström, J., Mäkinen, M.J., Kytölä, S., Sjöblom, T., Glimelius, B., Osterlund, P.J.

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Toxic injury from mercuric chloride in rat hepatocytes by NIEMINEN, A.-L, GORES, G. J, DAWSON, T. L, HERMAN, B, LEMASTERS, J. J

“…The relationship between cytosolic free Ca2+, mitochondrial membrane potential, ATP depletion, pyridine nucleotide fluorescence, cell surface blebbing, and…”
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Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: a laser scanning confocal microscopic study by Zahrebelski, G, Nieminen, A L, al-Ghoul, K, Qian, T, Herman, B, Lemasters, J J

“…The aim of this study was to evaluate changes in the subcellular organelles of cultured hepatocytes by laser scanning confocal microscopy during chemical…”
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Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes by Gores, G J, Nieminen, A L, Fleishman, K E, Dawson, T L, Herman, B, Lemasters, J J

“…A fluorometric assay using propidium iodide total fluorescence was utilized to quantitate cell viability in hepatocyte suspensions continuously. For viable…”
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