Search Results - "Niemi, TT"

Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro by Munsterhjelm, E., Niemi, T. T., Ylikorkala, O., Silvanto, M., Rosenberg, P. H.

“…Background:  Paracetamol (acetaminophen) is an effective analgesic and a weak inhibitor of cyclo‐oxygenase (COX). Clinically paracetamol is often used together…”
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Gelatin and Hydroxyethyl Starch, but Not Albumin, Impair Hemostasis After Cardiac Surgery by Niemi, Tomi T., Suojaranta-Ylinen, Raili T., Kukkonen, Sinikka I., Kuitunen, Anne H.

“…We investigated the effect of postoperative administration of colloids on hemostasis in 45 patients after cardiac surgery. Patients were randomized to receive…”
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Artificial colloids impair haemostasis. An in vitro study using thromboelastometry coagulation analysis by Niemi, T. T., Kuitunen, A. H.

“…Background:  Hydroxyethyl starch (HES) solutions impair haemostatic mechanisms. The impact of the degree of substitution (DS) of a HES solution on…”
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Dose-dependent inhibition of platelet function by acetaminophen in healthy volunteers by MUNSTERHJELM, Edward, MUNSTERHJELM, Nina M, NIEMI, Tomi T, YLIKORKALA, Olavi, NEUVONEN, Pertti J, ROSENBERG, Per H

“…Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous…”
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Patient Satisfaction with Postoperative Pain Management—Effect of Preoperative Factors by Niemi-Murola, Leila, Pöyhiä, Reino, Onkinen, Kaarina, Rhen, Birthe, Mäkelä, Arja, Niemi, Tomi T.

“…Patients often suffer from inadequate treatment of postoperative pain. The purpose of this study was to survey the factors affecting patient satisfaction with…”
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The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm by Niemi, Tomi T, Munsterhjelm, Edward, Pöyhiä, Reino, Hynninen, Marja S, Salmenperä, Markku T

“…N-acetylcysteine (NAC) may offer renal and hepatic protection during surgery, but in experimental studies it has been shown to impair coagulation. Since very…”
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Comparison of ropivacaine 2 mg ml(-1) and prilocaine 5 mg ml(-1) for i.v. regional anaesthesia in outpatient surgery by Niemi, T T, Neuvonen, P J, Rosenberg, P H

“…Ropivacaine 2 mg ml(-1) (0.2%) provides longer-lasting analgesia after deflation of the tourniquet cuff, with fewer side-effects, than lidocaine 5 mg ml(-1)…”
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Effects of combined balanced colloid and crystalloid on rotational thromboelastometry in vitro by Lindroos, A-C, Schramko, AA, Niiya, T, Suojaranta-Ylinen, RT, Niemi, TT

“…Our objective was to investigate the in vitro effects of a totally balanced fluid concept on whole blood coagulation. Venous blood from 12 healthy volunteers…”
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Propacetamol augments inhibition of platelet function by diclofenac in volunteers by Munsterhjelm, E., Niemi, T.T., Syrjälä, M.T., Ylikorkala, O., Rosenberg, P.H.

“…Acetaminophen (paracetamol) enhances the analgesic effect of non-steroidal anti-inflammatory drugs (NSAIDs). Acetaminophen is a weak inhibitor of…”
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Platelet dysfunction after intravenous ketorolac or propacetamol by Niemi, T. T., Backman, J. T., Syrjälä, M. T., Viinikka, L. U., Rosenberg, P. H.

“…Background: Paracetamol is a weak cyclo‐oxygenase inhibitor in vitro. A recent study in children has shown that high doses of paracetamol are effective and…”
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Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty by Niemi, T. T., Pitkänen, M., Syrjälä, M., Rosenberg, P. H.

“…Hypotensive epidural anaesthesia (HEA) is a technique for reducing peroperative blood loss by significantly lowering mean arterial pressure (MAP). Thirty…”
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Hydroxyethyl starch impairs in vitro coagulation by Niemi, T. T., Kuitunen, A. H.

“…Background: Artificial colloids affect haemostasis. Particularly hydroxyethyl starch (HES) solutions may have detrimental effects on haemostatic mechanisms…”
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Comparison of the effect of intravenous ketoprofen, ketorolac and diclofenac on platelet function in volunteers by NIEMI, T. T., TAXELL, C., ROSENBERG, P. H.

“…Background: Nonsteroidal anti–inflammatory drugs (NSAIDs) inhibit prostaglandin synthesis which may result in impaired platelet function. Because NSAIDs have…”
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Whole blood hypercoagulability despite anticoagulation during mechanical cardiac assist by Niemi, TT, Kukkonen, SI, Hämmäinen, PT, Suojaranta-Ylinen, RT, Sipponen, JT

“…We report hypercoagulability despite activated partial thromboplastin time (APTT)-guided heparin treatment during Berlin Heart®-supported circulation in a…”
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Epinephrine added to a lumbar epidural infusion of a small-dose ropivacaine-fentanyl mixture after arterial bypass surgery of the lower extremities by Förster, J. G., Niemi, T. T., Aromaa, U., Neuvonen, P. J., Seppälä, T. A., Rosenberg, P. H.

“…Background:  The addition of epinephrine (2 µg·ml−1) to a thoracic epidural infusion of an opioid‐local anesthetic mixture improves analgesia. Here, we studied…”
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Haemostatic changes caused by i.v. regional anaesthesia with lignocaine by Niemi, T T, Kuitunen, A H, Vahtera, E M, Rosenberg, P H

“…The various components of i.v. regional anaesthesia (IVRA), that is ischaemia, tourniquet compression and the presence of high concentrations of local…”
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