Search Results - "Nielsen, Stine N."

Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction by Schmiegelow, Kjeld, Nielsen, Stine N, Frandsen, Thomas L, Nersting, Jacob

“…The antileukemic mechanisms of 6-mercaptopurine (6MP) and methotrexate (MTX) maintenance therapy are poorly understood, but the benefits of several years of…”
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DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis by Toksvang, Linea N., Grell, Kathrine, Nersting, Jacob, Degn, Matilda, Nielsen, Stine N., Abrahamsson, Jonas, Lund, Bendik, Kanerva, Jukka, Jónsson, Ólafur G., Lepik, Kristi, Vaitkevičienė, Goda, Griškevičius, Laimonas, Quist-Paulsen, Petter, Vora, Ajay, Moorman, Anthony V., Murdy, Daniel, Zimmermann, Martin, Möricke, Anja, Bostrom, Bruce, Joshi, Jaitri, Hjalgrim, Lisa L., Dalhoff, Kim P., Als-Nielsen, Bodil, Schmiegelow, Kjeld

“…Methotrexate/6-mercaptopurine maintenance therapy improves acute lymphoblastic leukemia (ALL) outcome. Cytotoxicity is mediated by DNA incorporation of…”
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Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites by Toksvang, Linea Natalie, Pietri, Silvia, Nielsen, Stine N., Nersting, Jacob, Albertsen, Birgitte K., Wehner, Peder S., Rosthøj, Steen, Lähteenmäki, Päivi M., Nilsson, Daniel, Nystad, Tove A., Grell, Kathrine, Frandsen, Thomas L., Schmiegelow, Kjeld

“…Background Hepatic sinusoidal obstruction syndrome (SOS) during treatment of childhood acute lymphoblastic leukemia (ALL) has mainly been associated with…”
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Pharmacokinetics of 6-Thioguanine and 6-Mercaptopurine Combination Maintenance Therapy of Childhood ALL: Hypothesis and Case Report by Nielsen, Stine N, Frandsen, Thomas L, Nersting, Jacob, Hjalgrim, Lisa L, Schmiegelow, Kjeld

“…Methotrexate/6-mercaptopurine maintenance therapy of childhood acute lymphoblastic leukemia is challenged by treatment-related hepatotoxicity, failure to…”
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Children with low‐risk acute lymphoblastic leukemia are at highest risk of second cancers by Nielsen, Stine N., Eriksson, Frank, Rosthoej, Susanne, Andersen, Mette K., Forestier, Erik, Hasle, Henrik, Hjalgrim, Lisa L., Aasberg, Ann, Abrahamsson, Jonas, Heyman, Mats, Jónsson, Ólafur G., Pruunsild, Kaie, Vaitkeviciené, Goda E., Vettenranta, Kim, Schmiegelow, Kjeld

“…Background The improved survival rates for childhood acute lymphoblastic leukemia (ALL) may be jeopardized by the development of a second cancer, which has…”
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