Search Results - "Nielsen, Nis Valentin"
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Fluorescent activity-based probe for the selective detection of Factor VII activating protease (FSAP) in human plasma
Published in Thrombosis research (01-10-2019)“…AbstractThe zymogen form of circulating Factor VII activating protease (FSAP) is activated by histones that are released as a consequence of tissue damage or…”
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Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)
Published in Scientific reports (12-12-2019)“…Factor VII (FVII) activating protease (FSAP) is a circulating serine protease. Human genetic studies, based on the Marburg I (MI) (Gly221Glu, chymotrypsin…”
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Design and Characterization of a New pVII Combinatorial Phage Display Peptide Library for Protease Substrate Mining Using Factor VII Activating Protease (FSAP) as Model
Published in Chembiochem : a European journal of chemical biology (01-07-2020)“…We describe a novel, easy and efficient combinatorial phage display peptide substrate‐mining method to map the substrate specificity of proteases. The peptide…”
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Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice
Published in Pflügers Archiv (01-02-2022)“…Proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases is thought to contribute to renal sodium retention in…”
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Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells
Published in Atherosclerosis (01-10-2017)“…The factor VII activating protease (FSAP) knockout mice have a bigger neointima after vascular injury and a larger infarct volume after stroke. The Marburg I…”
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Identification of a Phage Display-Derived Peptide Interacting with the N‑Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation
Published in ACS chemical biology (16-09-2022)“…Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP–/– mice and humans deficient in…”
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