Search Results - "Nielsen, Jan M."

Radiofrequency ablation lesions in low-, intermediate-, and normal-voltage myocardium: an in vivo study in a porcine heart model by Tofig, Bawer J, Lukac, Peter, Nielsen, Jan M, Hansen, Esben S S, Tougaard, Rasmus S, Jensen, Henrik K, Nielsen, Jens C, Kristiansen, Steen B

“…Abstract Aims Contact force (CF) between radiofrequency (RF) ablation catheter and myocardium and ablation index (AI) correlates with RF lesion depth and width…”
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Morpho-functional characterization of the systemic venous pole of the reptile heart by Jensen, Bjarke, Vesterskov, Signe, Boukens, Bastiaan J., Nielsen, Jan M., Moorman, Antoon F. M., Christoffels, Vincent M., Wang, Tobias

“…Mammals evolved from reptile-like ancestors, and while the mammalian heart is driven by a distinct sinus node, a sinus node is not apparent in reptiles. We…”
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Effects of Bisoprolol and Losartan Treatment in the Hypertrophic and Failing Right Heart by Andersen, Stine, MS, Schultz, Jacob Gammelgaard, MS, Andersen, Asger, MD, PhD, Ringgaard, Steffen, PhD, Nielsen, Jan M., MD, PhD, Holmboe, Sarah, MD, Vildbrad, Mads D., MS, de Man, Frances S., PhD, Bogaard, Harm J., MD, PhD, Vonk-Noordegraaf, Anton, MD, PhD, Nielsen-Kudsk, Jens Erik, MD, DMSc

“…Abstract Background Sympathetic adrenergic stimulation and the renin-angiotensin-aldosterone system are highly elevated in right heart failure. We evaluated if…”
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Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles by Nielsen, Ebbe J. B, Nielsen, Jan M, Becker, Daniel, Karlas, Alexander, Prakash, Hridayesh, Glud, Sys Z, Merrison, Jonathan, Besenbacher, Flemming, Meyer, Thomas F, Kjems, Jørgen, Howard, Kenneth A

“…Purpose This work describes the production and application of an aerosolised formulation of chitosan nanoparticles for improved pulmonary siRNA delivery and…”
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Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation by Bartels, Emil D, Nielsen, Jan M, Hellgren, Lars I, Ploug, Thorkil, Nielsen, Lars B

“…Obesity causes lipid accumulation in the heart and may lead to lipotoxic heart disease. Traditionally, the size of the cardiac triglyceride pool is thought to…”
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Is a ring of gold what we waited for to treat atrial fibrillation? by Nielsen, Jan M, Nielsen, Jens Cosedis

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Identification of the building blocks of ventricular septation in monitor lizards (Varanidae) by Hanemaaijer, Jermo, Gregorovicova, Martina, Nielsen, Jan M, Moorman, Antoon F M, Wang, Tobias, Planken, R Nils, Christoffels, Vincent M, Sedmera, David, Jensen, Bjarke

“…Among lizards, only monitor lizards (Varanidae) have a functionally divided cardiac ventricle. The division results from the combined function of three partial…”
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Acute effects of sildenafil and dobutamine in the hypertrophic and failing right heart in vivo by Andersen, Asger, Nielsen, Jan M., Rasalingam, Sivagowry, Sloth, Erik, Nielsen-Kudsk, Jens Erik

“…The purpose of this study was to investigate whether acute intravenous administration of the phosphodiesterase type 5 (PDE-5) inhibitor sildenafil in a single…”
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How the python heart separates pulmonary and systemic blood pressures and blood flows by Jensen, Bjarke, Nielsen, Jan M, Axelsson, Michael, Pedersen, Michael, Löfman, Carl, Wang, Tobias

“…The multiple convergent evolution of high systemic blood pressure among terrestrial vertebrates has always been accompanied by lowered pulmonary pressure. In…”
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Levosimendan Prevents Pressure-Overload-induced Right Ventricular Failure by Hillgaard, Thomas Krarup, Andersen, Asger, Andersen, Stine, Vildbrad, Mads D, Ringgaard, Steffen, Nielsen, Jan M, Nielsen-Kudsk, Jens E

“…BACKGROUND:We investigated if chronic levosimendan treatment can prevent and revert pressure-overload–induced right ventricular hypertrophy and failure in…”
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Remote Cardioprotection by Transfer of Coronary Effluent from Ischemic Preconditioned Rabbit Heart Preserves Mitochondrial Integrity and Function via Adenosine Receptor Activation by Leung, Chung Ho, Wang, Lixing, Nielsen, Jan M., Tropak, Michael B., Fu, Yana Y., Kato, Hideyuki, Callahan, John, Redington, Andrew N., Caldarone, Christopher A.

“…Background Coronary effluent from an isolated perfused heart undergoing ischemic preconditioning can be transferred to precondition another naïve isolated…”
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Evaluation of cardiac electrophysiological properties in an experimental model of right ventricular hypertrophy and failure by Schultz, Jacob G, Andersen, Stine, Andersen, Asger, Nielsen-Kudsk, Jens Erik, Nielsen, Jan M

“…Malignant arrhythmias are a major cause of sudden cardiac death in adults with congenital heart disease. We developed a model to serially investigate…”
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The Effects of Cyclic Guanylate Cyclase Stimulation on Right Ventricular Hypertrophy and Failure Alone and in Combination With Phosphodiesterase-5 Inhibition by Andersen, Asger, Nielsen, Jan M, Holmboe, Sarah, Vildbrad, Mads D, Nielsen-Kudsk, Jens E

“…BACKGROUND:We investigated if soluble guanylate cyclase stimulation either alone or in combination with phosphodiesterase-5 (PDE5) inhibition could prevent…”
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Blockage of receptor for advanced glycation end products prevents development of cardiac dysfunction in db/db type 2 diabetic mice by Nielsen, Jan M., Kristiansen, Steen B., Nørregaard, Rikke, Andersen, Claus L., Denner, Larry, Nielsen, Torsten T., Flyvbjerg, Allan, Bøtker, Hans E.

“…Aims Activation of the receptor for advanced glycation end products (RAGE) is associated with long-term complications in diabetes mellitus. In this study, we…”
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Acute effects of levosimendan in experimental models of right ventricular hypertrophy and failure by Vildbrad, Mads D., Andersen, Asger, Holmboe, Sarah, Ringgaard, Steffen, Nielsen, Jan M., Nielsen-Kudsk, Jens Erik

“…Pulmonary arterial hypertension (PAH) is a fatal disease, and the ultimate cause of death is right ventricular (RV) failure. In this study, we investigated the…”
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Minimal engraftment of human CD34+ cells mobilized from healthy donors in the infarcted heart of athymic nude rats by Sondergaard, Claus S, Bonde, Jesper, Dagnaes-Hansen, Frederik, Nielsen, Jan M, Zachar, Vladimir, Holm, Mette, Hokland, Peter, Pedersen, Lene

“…Cell-based regenerative therapy may be useful for treatment of acute myocardial infarction (AMI). Animal xenograft models are ideally suited for preclinical…”
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Iloprost improves ventricular function in the hypertrophic and functionally impaired right heart by direct stimulation by Holmboe, Sarah, Andersen, Asger, Vildbrad, Mads D., Nielsen, Jan M., Ringgaard, Steffen, Nielsen-Kudsk, Jens E.

“…Right heart function is an important predictor of morbidity and mortality in patients suffering from pulmonary arterial hypertension and congenital heart…”
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PO-02-109 ABLATION INDEX, CONTACT FORCE AND DURATION: A COMPARATIVE BEATING HEART STUDY by Tofig, Bawer J., Lukac, Peter, Nielsen, Jan M., Hansen, Esben S., Bøgh, Nikolaj, Tougaard, Rasmus S., Kristiansen, Steen B.

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Commentary on "Direct comparison of magnetic resonance imaging and conductance microcatheter in the evaluation of left ventricular function in mice" by Jacoby et al. in Basic Res Cardiol 101:87-95 (2006) by Nielsen, Jan M, Redington, Andrew N, Kristiansen, Steen B

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PO-03-103 REDO ABLATION IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION WITH PULMONARY VEIN ISOLATION UTILIZING BIATRIAL ELECTROGRAM DISPERSION MAPPING by Khan, Abdulhaseeb, Zaman, Junaid A., Nielsen, Jan M., Kristiansen, Steen B., Kronborg, Mads B., Witt, Christoffer T., Gerdes, Christian, Kristensen, Jens, Jensen, Henrik K., Agarwal, Sharad, Lukac, Peter

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