Search Results - "Nielsen, Finn C."

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis by Gregory, Adam P., Dendrou, Calliope A., Attfield, Kathrine E., Haghikia, Aiden, Xifara, Dionysia K., Butter, Falk, Poschmann, Gereon, Kaur, Gurman, Lambert, Lydia, Leach, Oliver A., Prömel, Simone, Punwani, Divya, Felce, James H., Davis, Simon J., Gold, Ralf, Nielsen, Finn C., Siegel, Richard M., Mann, Matthias, Bell, John I., McVean, Gil, Fugger, Lars

“…Genome-wide association studies in combination with functional analyses identify a genetic variant that explains why anti-tumour necrosis factor therapy, used…”
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Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways by Gabrielaite, Migle, Johansen, Helle K., Molin, Søren, Nielsen, Finn C., Marvig, Rasmus L.

“…Bacterial airway infections, predominantly caused by P. aeruginosa , are a major cause of mortality and morbidity of CF patients. While short insertions and…”
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A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000–2010: The largest registry‐based study to date by Garnaes, Emilie, Kiss, Katalin, Andersen, Luise, Therkildsen, Marianne H., Franzmann, Maria B., Filtenborg‐Barnkob, Bettina, Hoegdall, Estrid, Krenk, Lene, Josiassen, Michael, Lajer, Christel B., Specht, Lena, Frederiksen, Kirsten, Friis‐Hansen, Lennart, Nielsen, Finn C., Kjaer, Susanne K., Norrild, Bodil, von Buchwald, Christian

“…The aim was to explore whether the incidence of tonsillar squamous cell carcinomas (TSCCs) increased in Eastern Denmark, 2000–2010, and whether human…”
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IGF2 mRNA-binding protein 2: biological function and putative role in type 2 diabetes by Christiansen, Jan, Kolte, Astrid M, Hansen, Thomas v O, Nielsen, Finn C

“…Recent genome-wide association (GWA) studies of type 2 diabetes (T2D) have implicated IGF2 mRNA-binding protein 2 (IMP2/IGF2BP2) as one of the several factors…”
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Deep targeted sequencing of TP53 in chronic lymphocytic leukemia: clinical impact at diagnosis and at time of treatment by Brieghel, Christian, Kinalis, Savvas, Yde, Christina W, Schmidt, Ane Y, Jønson, Lars, Andersen, Michael A, da Cunha-Bang, Caspar, Pedersen, Lone B, Geisler, Christian H, Nielsen, Finn C, Niemann, Carsten U

“…In chronic lymphocytic leukemia, mutations and deletion of chromosome 17p are well-characterized biomarkers associated with poor progression-free and overall…”
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RNA-binding IMPs promote cell adhesion and invadopodia formation by Vikesaa, Jonas, Hansen, Thomas VO, Jønson, Lars, Borup, Rehannah, Wewer, Ulla M, Christiansen, Jan, Nielsen, Finn C

“…Oncofetal RNA‐binding IMPs have been implicated in mRNA localization, nuclear export, turnover and translational control. To depict the cellular actions of…”
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Collection of Blood, Saliva, and Buccal Cell Samples in a Pilot Study on the Danish Nurse Cohort: Comparison of the Response Rate and Quality of Genomic DNA by HANSEN, Thomas V. O, SIMONSEN, Mette K, NIELSEN, Finn C, ANDERSEN HUNDRUP, Yrsa

“…In this study, we compared the response rates of blood, saliva, and buccal cell samples in a pilot study on the Danish nurse cohort and examined the quantity…”
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Molecular Composition of IMP1 Ribonucleoprotein Granules by J⊘nson, Lars, Vikesaa, Jonas, Krogh, Anders, Nielsen, Lars K., Hansen, Thomas vO, Borup, Rehannah, Johnsen, Anders H., Christiansen, Jan, Nielsen, Finn C.

“…Localized mRNAs are transported to sites of local protein synthesis in large ribonucleoprotein (RNP) granules, but their molecular composition is incompletely…”
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Arachidonic and oleic acid exert distinct effects on the DNA methylome by Silva-Martínez, Guillermo A., Rodríguez-Ríos, Dalia, Alvarado-Caudillo, Yolanda, Vaquero, Alejandro, Esteller, Manel, Carmona, F. Javier, Moran, Sebastian, Nielsen, Finn C., Wickström-Lindholm, Marie, Wrobel, Katarzyna, Wrobel, Kazimierz, Barbosa-Sabanero, Gloria, Zaina, Silvio, Lund, Gertrud

“…Abnormal fatty acid metabolism and availability are landmarks of metabolic diseases, which in turn are associated with aberrant DNA methylation profiles. To…”
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Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study by Nørøxe, Dorte S., Yde, Christina W., Østrup, Olga, Michaelsen, Signe R., Schmidt, Ane Y., Kinalis, Savvas, Torp, Mathias H., Skjøth‐Rasmussen, Jane, Brennum, Jannick, Hamerlik, Petra, Poulsen, Hans S., Nielsen, Finn C., Lassen, Ulrik

“…Landscape of somatic copy number alterations, mutations, and fusions in selected genes in newly diagnosed glioblastoma patients. The most frequent aberrations…”
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Variant in ERAP1 promoter region is associated with low expression in a patient with a Behçet-like MHC-I-opathy by Dimopoulou, Chrysoula, Lundgren, Jens D, Sundal, Jon, Ullum, Henrik, Aukrust, Pål, Nielsen, Finn C, Marvig, Rasmus L

“…Behçet disease (BD) is an immune-mediated disease. The cause of BD remains unknown, but the existence of multiple pathological pathways is suspected, including…”
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MicroRNA Expression in Melanocytic Nevi: The Usefulness of Formalin-Fixed, Paraffin-Embedded Material for miRNA Microarray Profiling by Glud, Martin, Klausen, Mikkel, Gniadecki, Robert, Rossing, Maria, Hastrup, Nina, Nielsen, Finn C., Drzewiecki, Krzysztof T.

“…MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate cellular differentiation, proliferation, and apoptosis. MiRNAs are expressed in a…”
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Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation by Rossing, Maria, Albrechtsen, Anders, Skytte, Anne-Bine, Jensen, Uffe B, Ousager, Lilian B, Gerdes, Anne-Marie, Nielsen, Finn C, Hansen, Thomas vO

“…Pathogenic germline mutations in the folliculin (FLCN) tumor suppressor gene predispose to Birt-Hogg-Dubé (BHD) syndrome, a rare disease characterized by the…”
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IMP3 RNP Safe Houses Prevent miRNA-Directed HMGA2 mRNA Decay in Cancer and Development by Jønson, Lars, Christiansen, Jan, Hansen, Thomas V.O., Vikeså, Jonas, Yamamoto, Yohei, Nielsen, Finn C.

“…The IMP3 RNA-binding protein is associated with metastasis and poor outcome in human cancer. Using solid cancer transcriptome data, we found that IMP3…”
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The trans fatty acid elaidate affects the global DNA methylation profile of cultured cells and in vivo by Flores-Sierra, José, Arredondo-Guerrero, Martín, Cervantes-Paz, Braulio, Rodríguez-Ríos, Dalia, Alvarado-Caudillo, Yolanda, Nielsen, Finn C, Wrobel, Katarzyna, Wrobel, Kazimierz, Zaina, Silvio, Lund, Gertrud

“…The deleterious effects of dietary trans fatty acids (tFAs) on human health are well documented. Although significantly reduced or banned in various countries,…”
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Downregulation of miR-125b in metastatic cutaneous malignant melanoma by Glud, Martin, Rossing, Maria, Hother, Christoffer, Holst, Line, Hastrup, Nina, Nielsen, Finn C, Gniadecki, Robert, Drzewiecki, Krzysztof T

“…This study aimed to identify microRNA species involved in the earliest metastatic event in cutaneous malignant melanoma (MM). Samples from 28 patients with MM…”
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Dwarfism and Impaired Gut Development in Insulin-Like Growth Factor II mRNA-Binding Protein 1-Deficient Mice by Hansen, Thomas V. O., Hammer, Niels A., Nielsen, Jacob, Madsen, Mette, Dalbaeck, Charlotte, Wewer, Ulla M., Christiansen, Jan, Nielsen, Finn C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Clusters of conserved beta cell marker genes for assessment of beta cell phenotype by Martens, Geert A, Jiang, Lei, Hellemans, Karine H, Stangé, Geert, Heimberg, Harry, Nielsen, Finn C, Sand, Olivier, Van Helden, Jacques, Van Lommel, Leentje, Schuit, Frans, Gorus, Frans K, Pipeleers, Daniel G

“…The aim of this study was to establish a gene expression blueprint of pancreatic beta cells conserved from rodents to humans and to evaluate its applicability…”
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Expression of oncofetal RNA‐binding protein CRD‐BP/IMP1 predicts clinical outcome in colon cancer by Dimitriadis, Euthymios, Trangas, Theoni, Milatos, Stavros, Foukas, Periklis G., Gioulbasanis, Ioannis, Courtis, Nelly, Nielsen, Finn C., Pandis, Nikos, Dafni, Urania, Bardi, Georgia, Ioannidis, Panayotis

“…The oncofetal CRD‐BP/IMP1 RNA binding protein regulates posttranscriptionally a handful of RNA transcripts, implicated in cell adhesion and invadopodia…”
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Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages by Rangel-Salazar, Rubén, Wickström-Lindholm, Marie, Aguilar-Salinas, Carlos A, Alvarado-Caudillo, Yolanda, Døssing, Kristina B V, Esteller, Manel, Labourier, Emmanuel, Lund, Gertrud, Nielsen, Finn C, Rodríguez-Ríos, Dalia, Solís-Martínez, Martha O, Wrobel, Katarzyna, Wrobel, Kazimierz, Zaina, Silvio

“…We previously showed that a VLDL- and LDL-rich mix of human native lipoproteins induces a set of repressive epigenetic marks, i.e. de novo DNA methylation,…”
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