Search Results - "Nielsen, Cole"
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Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Published in PLoS biology (01-12-2020)“…When the J-domain of the heat shock protein DnaJB1 is fused to the catalytic (C) subunit of cAMP-dependent protein kinase (PKA), replacing exon 1, this fusion…”
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Journal Article -
2
The Regulatory Subunit Type Iα of Protein Kinase A: A Study of Carney Complex and Acrodysostosis Mutations
Published in The FASEB journal (01-04-2017)“…Abstract only cAMP‐dependent Protein Kinase A (PKA), a tetrameric holoenzyme comprised of two Catalytic (C) and one dimer of Regulatory (R) subunits, is the…”
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Journal Article -
3
Structural analyses of the PKA RII[beta] holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Published in PLoS biology (28-12-2020)“…When the J-domain of the heat shock protein DnaJB1 is fused to the catalytic (C) subunit of cAMP-dependent protein kinase (PKA), replacing exon 1, this fusion…”
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Journal Article -
4
Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation
Published in Journal of molecular biology (04-12-2016)“…Most disease-related mutations that impair cAMP protein kinase A (PKA) signaling are present within the regulatory (R) PKA RI alpha-subunit (RIα). Although…”
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Journal Article -
5
Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation
Published in Journal of molecular biology (05-11-2016)“…Most disease related mutations that impair PKA signaling are present within the regulatory PKA RI alpha-subunit (RIα). Although mutations in the PRKAR1A gene…”
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Journal Article -
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The musical abilities and interests of junior high school pupils
Published 01-01-1932Get full text
Dissertation