Search Results - "Niekamp, Patrick"

Microbial Metabolite Dysbiosis and Colorectal Cancer by Niekamp, Patrick, Kim, Chang H

“…The global burden of colorectal cancer (CRC) is expected to continuously increase. Through research performed in the past decades, the effects of various…”
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Ceramides bind VDAC2 to trigger mitochondrial apoptosis by Dadsena, Shashank, Bockelmann, Svenja, Mina, John G. M., Hassan, Dina G., Korneev, Sergei, Razzera, Guilherme, Jahn, Helene, Niekamp, Patrick, Müller, Dagmar, Schneider, Markus, Tafesse, Fikadu G., Marrink, Siewert J., Melo, Manuel N., Holthuis, Joost C. M.

“…Ceramides draw wide attention as tumor suppressor lipids that act directly on mitochondria to trigger apoptotic cell death. However, molecular details of the…”
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Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow by Liu, Qingyang, Tabrez, Shams, Niekamp, Patrick, Kim, Chang H.

“…Innate lymphoid cells (ILCs), strategically positioned throughout the body, undergo population declines over time. A solution to counteract this problem is…”
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Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair by Niekamp, Patrick, Scharte, Felix, Sokoya, Tolulope, Vittadello, Laura, Kim, Yeongho, Deng, Yongqiang, Südhoff, Elisabeth, Hilderink, Angelika, Imlau, Mirco, Clarke, Christopher J., Hensel, Michael, Burd, Christopher G., Holthuis, Joost C. M.

“…Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell…”
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Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry by Niekamp, Patrick, Guzman, Gaelen, Leier, Hans C, Rashidfarrokhi, Ali, Richina, Veronica, Pott, Fabian, Barisch, Caroline, Holthuis, Joost C M, Tafesse, Fikadu G

“…Phagocytosis by alveolar macrophages is the obligate first step in ( ) infection, yet the mechanism underlying this process is incompletely understood. Here,…”
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The Squeaky Yeast Gets Greased: The Roles of Host Lipids in the Clearance of Pathogenic Fungi by Guzman, Gaelen, Niekamp, Patrick, Tafesse, Fikadu Geta

“…Fungal infections remain a global health threat with high morbidity and mortality. The human immune system must, therefore, perpetually defend against invasive…”
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Ca2+‐activated Sphingomyelin Scrambling and Turnover Mediate ESCRT‐independent Lysosomal Repair by Holthuis, Joost, Niekamp, Patrick

“…Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell…”
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Ca 2+ -activated Sphingomyelin Scrambling and Turnover Mediate ESCRT-independent Lysosomal Repair by Holthuis, Joost, Niekamp, Patrick

“…Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell…”
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Sphingolipids: A double-edged sword in the defense against Mycobacterium tuberculosis by Guzman, Gaelen D, Leier, Hans, Niekamp, Patrick, Holthuis, Joost, Tafesse, Fikadu G.

“…Mycobacterium tuberculosis (Mtb) is a pathogen with a massive global health impact, and yet fundamental questions remain regarding the underlying mechanisms of…”
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Ca 2+ -activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair by Niekamp, Patrick, Scharte, Felix, Sokoya, Tolulope, Vittadello, Laura, Kim, Yeongho, Deng, Yongqiang, Südhoff, Elisabeth, Hilderink, Angelika, Imlau, Mirco, Clarke, Christopher J, Hensel, Michael, Burd, Christopher G, Holthuis, Joost C M

“…Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell…”
Get full text