Search Results - "Niehans, G A"

Human lung carcinomas express Fas ligand by NIEHANS, G. A, BRUNNER, T, FRIZELLE, S. P, LISTON, J. C, SALERNO, C. T, KNAPP, D. J, GREEN, D. R, KRATZKE, R. A

“…To reach a clinically detectable size, neoplasms must be able to suppress or evade a host immune response. Activated T cells may enter apoptosis in the…”
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Stability of HER-2/neu expression over time and at multiple metastatic sites by Niehans, G A, Singleton, T P, Dykoski, D, Kiang, D T

“…Amplification and over-expression of the HER-2/neu oncogene (also known as c-erbB-2) occurs in 20%-30% of invasive breast carcinomas. The extent to which…”
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Fas ligand expression in the bone marrow in myelodysplastic syndromes correlates with FAB subtype and anemia, and predicts survival by GUPTA, P, NIEHANS, G. A, LEROY, S. C, GUPTA, K, MORRISON, V. A, SCHULTZ, C, KNAPP, D. J, KRATZKE, R. A

“…Increased apoptosis in the bone marrow (BM) may contribute to the cytopenias that occur in myelodysplastic syndromes (MDS). The Fas receptor, Fas ligand (FasL)…”
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G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder by NIEHANS, G. A, KRATZKE, R. A, FROBERG, M. K, AEPPLL, D. M, NGUYEN, P. L, GERADTS, J

“…The G1 cell cycle checkpoint regulates entry into S phase for normal cells. Components of the G1 checkpoint, including retinoblastoma (Rb) protein, cyclin D1…”
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Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin) by Niehans, GA, Cherwitz, DL, Staley, NA, Knapp, DJ, Dalmasso, AP

“…Normal human tissues express membrane-associated complement inhibitory proteins that protect these tissues from damage by autologous complement. To determine…”
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Heterogeneity of mucin gene expression in normal and neoplastic tissues by HO, S. B, NIEHANS, G. A, LYFTOGT, C, PEI SHA YAN, CHERWITZ, D. L, GUM, E. T, RAJVIR DAHIYA, KIM, Y. S

“…To determine the relative expression of distinct mucin genes in normal and neoplastic tissue, antibodies and cDNA probes that recognize the core tandem repeat…”
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Mucin gene expression in normal, preneoplastic, and neoplastic human gastric epithelium by HO, S. B, SHEKELS, L. L, TORIBARA, N. W, KIM, Y. S, LYFTOGT, C, CHERWITZ, D. L, NIEHANS, G. A

“…Mucins synthesized by malignant cells may contribute (via decreased cellular adhesion and immune recognition) to cancer invasion and metastases. Human mucins…”
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Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression by Ho, S B, Roberton, A M, Shekels, L L, Lyftogt, C T, Niehans, G A, Toribara, N W

“…Secretory mucins play an important role in gastric cytoprotection and are derived from a heterogeneous family of genes. The aim of this study was to determine…”
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Epidermal growth factor receptor and transforming growth factor alpha expression in papillary and nonpapillary renal cell carcinoma: correlation with metastatic behavior and prognosis by UHLMAN, D. L, NGUYEN, P, MANIVEL, J. C, GANG ZHANG, HAGEN, K, FRALEY, E, AEPPLI, D, NIEHANS, G. A

“…Papillary renal carcinomas are a cytogenetically unique subset of renal carcinomas that have been reported to be clinically less aggressive. We have examined…”
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Do molecular markers predict survival in non-small-cell lung cancer ? by GREATENS, T. M, NIEHANS, G. A, RUBINS, J. B, JESSURUN, J, KRATZKE, R. A, MADDAUS, M. A, NIEWOEHNER, D. E

“…Patients with non-small-cell lung cancer (NSCLC) survive for variable lengths of time, even when adjustment is made for pathological stage. Numerous reports…”
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Expression of epidermal growth factor receptor in invasive transitional cell carcinoma of the urinary bladder. A multivariate survival analysis by Nguyen, P L, Swanson, P E, Jaszcz, W, Aeppli, D M, Zhang, G, Singleton, T P, Ward, S, Dykoski, D, Harvey, J, Niehans, G A

“…Epidermal growth factor receptor (EGFR) immunoreactivity was evaluated in 85 cases of invasive transitional cell carcinoma of the bladder. The impact of EGFR…”
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The role of ilioinguinal lymphadenectomy and significance of histological differentiation in treatment of carcinoma of the penis by Fraley, E E, Zhang, G, Manivel, C, Niehans, G A

“…We reviewed retrospectively the medical records of 58 patients treated for squamous cell carcinoma of the penis who were followed for more than 3 years or…”
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Basaloid squamous carcinoma: A clinical comparison of two histologic types with poorly differentiated squamous cell carcinoma by WINZENBURG, SANDRA M., NIEHANS, GLORIA A., GEORGE, EVAN, DALY, KATHLEEN, ADAMS, GEORGE L.

“…Basaloid squamous carcinoma (BSC) of the head and neck has been shown to have a poor prognosis when compared with conventional squamous cell carcinoma (SCC)…”
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Association of immunohistochemical staining for p53 with metastatic progression and poor survival in patients with renal cell carcinoma by Uhlman, D L, Nguyen, P L, Manivel, J C, Aeppli, D, Resnick, J M, Fraley, E E, Zhang, G, Niehans, G A

“…Mutations of the p53 gene have been found in many types of human tumors. In some tumors, p53 gene mutations are associated with advanced disease and poor…”
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Prognostic variables in male breast cancer by Clark, J L, Nguyen, P L, Jaszcz, W B, Jatoi, A, Niehans, G A

“…The prognostic role of ploidy status, S phase fraction, estrogen and progesterone receptor status, and the expression of p53 and erbB-2 protein in male breast…”
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Immunohistochemical study of chondroitin-6-sulphate and tenascin in the larynx: a loss of chondroitin-6-sulphate expression accompanies squamous cell carcinoma invasion by Uhlman, Dorothy L., Niehans, Gloria A.

“…Chondroitin 6‐sulphate is a glycosaminoglycan component of both cell membrane and basement membrane proteoglycans. In vitro it can inhibit tenascin, a molecule…”
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Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides by Cham, P.M.H., Niehans, G.A., Foman, N., Suwattee, P.

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Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors : correlation with retinoblastoma protein expression by GERADTS, J, KRATZKE, R. A, NIEHANS, G. A, LINCOLN, C. E

“…The retinoblastoma (RB) and cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) tumor suppressor genes play important roles in…”
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Activation of c-erbB-2 and prognosis in ovarian carcinoma. Comparison with histologic type, grade, and stage by Singleton, T P, Perrone, T, Oakley, G, Niehans, G A, Carson, L, Cha, S S, Strickler, J G

“…Prior reports suggested that measuring c-erbB-2 activation in ovarian carcinomas might be valuable in predicting prognosis. The authors attempted to confirm…”
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Immunohistochemical identification of P-glycoprotein in previously untreated, diffuse large cell and immunoblastic lymphomas by NIEHANS, G. A, JASZCZ, W, BRUNETTO, V, PERRI, R. T, GAJL-PECZALSKA, K, WICK, M. R, TSURUO, T, BLOOMFIELD, C. D

“…Expression of P-glycoprotein has been linked to multidrug resistance in cancer cell lines and human tumors. We investigated the frequency and clinical…”
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