Search Results - "Niedernhofer, L.J."

MOLECULAR PATHOLOGY ENDPOINTS USEFUL FOR AGING STUDIES by Niedernhofer, L.J, Kirkland, J.L, Ladiges, W

“…Highlights • Designing clinical trials against fundamental processes of aging is challenging. • There is no measure of biological age, thus proxy measures are…”
Get full text

Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics by Hartman, R, Patil, P, Tisherman, R, St Croix, C, Niedernhofer, L J, Robbins, P D, Ambrosio, F, Van Houten, B, Sowa, G, Vo, N

“…Robust cellular bioenergetics is vital in the energy-demanding process of maintaining matrix homeostasis in the intervertebral disc. Age-related decline in…”
Get full text

The evolving microenvironment of the human hepatocyte: Healthy vs. cirrhotic liver vs. isolated cells by Kirchner, V.A., Tak, E., Kim, K., LeCluyse, E.L., Niedernhofer, L.J., Soldatow, V., Lee, J., Kim, J., Tolar, J., Song, G.W., Pruett, T.L.

“…[Display omitted] •Healthy liver is characterized by low oxidative stress phenotype, robust metabolism and limited matrix turnover.•PHHs from healthy donors…”
Get full text