Search Results - "Niedermeier, Kristina M"
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Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease
Published in Nature communications (16-08-2022)“…Parkinson’s disease (PD) as a progressive neurodegenerative disorder arises from multiple genetic and environmental factors. However, underlying pathological…”
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A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons
Published in Translational psychiatry (13-02-2020)“…Neurodevelopmental disorders are heterogeneous and identifying shared genetic aetiologies and converging signalling pathways affected could improve disease…”
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Meis1 : effects on motor phenotypes and the sensorimotor system in mice
Published in Disease models & mechanisms (01-08-2017)“…encodes a developmental transcription factor and has been linked to restless legs syndrome (RLS) in genome-wide association studies. RLS is a movement disorder…”
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Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors
Published in Frontiers in behavioral neuroscience (12-11-2015)“…Adult neurogenesis occurs in the adult mammalian subventricular zone (SVZ) along the walls of the lateral ventricles and the subgranular zone (SGZ) of the…”
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Analysis of Neuropsychiatric Disease-Related Functional Neuroanatomical Markers in Mice
Published in Current protocols in mouse biology (01-03-2018)“…A better alignment of preclinical and clinical neurobiological measures could help improve neuropsychiatric disease therapeutic development. This unit…”
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