Search Results - "Niedermayer, Kathrin"
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Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesis
Published in Gene Expression Patterns (01-12-2021)“…Galloway-Mowat syndrome (GAMOS) is a rare developmental disease. Patients suffer from congenital brain anomalies combined with renal abnormalities often…”
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Journal Article -
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Dual PARP and RAD51 Inhibitory Drug Conjugates Show Synergistic and Selective Effects on Breast Cancer Cells
Published in Biomolecules (Basel, Switzerland) (03-07-2021)“…The genetic principle of synthetic lethality has most successfully been exploited in therapies engaging Poly-ADP-ribose-polymerase (PARP) inhibitors to treat…”
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Combined inhibition of RAD51 and CHK1 causes synergistic toxicity in cisplatin resistant cancer cells by triggering replication fork collapse
Published in International journal of cancer (06-09-2024)“…The therapeutic efficacy of the anticancer drug cisplatin is limited by acquired drug resistance. Cisplatin forms DNA crosslinks, that, if not removed, lead to…”
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Journal Article