Search Results - "Niederkofler, Eric E"

Investigating Diversity in Human Plasma Proteins by Nedelkov, Dobrin, Kiernan, Urban A., Niederkofler, Eric E., Tubbs, Kemmons A., Nelson, Randall W., Cantor, Charles R.

“…Plasma proteins represent an important part of the human proteome. Although recent proteomics research efforts focus largely on determining the overall number…”
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Targeted selected reaction monitoring mass spectrometric immunoassay for insulin-like growth factor 1 by Niederkofler, Eric E, Phillips, David A, Krastins, Bryan, Kulasingam, Vathany, Kiernan, Urban A, Tubbs, Kemmons A, Peterman, Scott M, Prakash, Amol, Diamandis, Eleftherios P, Lopez, Mary F, Nedelkov, Dobrin

“…Insulin-like growth factor 1 (IGF1) is an important biomarker of human growth disorders that is routinely analyzed in clinical laboratories. Mass…”
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Detection of novel truncated forms of human serum amyloid A protein in human plasma by Kiernan, Urban A., Tubbs, Kemmons A., Nedelkov, Dobrin, Niederkofler, Eric E., Nelson, Randall W.

“…Serum amyloid A protein (SAA) is a human plasma protein that has been recognized as potential biomarker of multiple ailments including myocardial infarction,…”
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Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins by Niederkofler, Eric E, Tubbs, Kemmons A, Kiernan, Urban A, Nedelkov, Dobrin, Nelson, Randall W

“…Novel mass spectrometric immunoassays (MSIAs) for the isolation and structural characterization of plasma apolipoprotein A-I (apoA-I), apoA-II, and apoE have…”
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Top-down mass spectrometric immunoassay for human insulin and its therapeutic analogs by Nedelkov, Dobrin, Niederkofler, Eric E., Oran, Paul E., Peterman, Scott, Nelson, Randall W.

“…Measurement of insulin and its therapeutic analogs is important in diabetes, hypoglycemia, sports anti-doping and toxicology. Commercial insulin immunoassays…”
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Insulin detemir does not cross the human placenta by Suffecool, Katarzyna, Rosenn, Barak, Niederkofler, Eric E, Kiernan, Urban A, Foroutan, Janelle, Antwi, Kwasi, Ribar, Amanda, Bapat, Priya, Koren, Gideon

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Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry by Reverter-Branchat, Gemma, Groessl, Michael, Nakas, Christos T, Prost, Jean-Christophe, Antwi, Kwasi, Niederkofler, Eric E., Bally, Lia

“…Insulin degludec is an ultra-long-acting insulin analogue that is increasingly being used in diabetes due to its favourable efficacy and safety profile. Thus,…”
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An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM) by Peterman, Scott, Niederkofler, Eric E., Phillips, David A., Krastins, Bryan, Kiernan, Urban A., Tubbs, Kemmons A., Nedelkov, Dobrin, Prakash, Amol, Vogelsang, Maryann S., Schoeder, Tara, Couchman, Lewis, Taylor, David R., Moniz, Cajetan F., Vadali, Gouri, Byram, Gregory, Lopez, Mary F.

“…The detection and quantification of insulin and its therapeutic analogs is important for medical, sports doping, and forensic applications. Synthetic variants…”
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Detection of endogenous B-type natriuretic peptide at very low concentrations in patients with heart failure by Niederkofler, Eric E, Kiernan, Urban A, O'Rear, Jessica, Menon, Santosh, Saghir, Syed, Protter, Andrew A, Nelson, Randall W, Schellenberger, Ute

“…The myocardium secretes B-type natriuretic peptide (BNP) in response to stimuli associated with heart failure (HF). However, high immunoreactive-BNP levels in…”
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Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum by Krastins, Bryan, Prakash, Amol, Sarracino, David A., Nedelkov, Dobrin, Niederkofler, Eric E., Kiernan, Urban A., Nelson, Randall, Vogelsang, Maryann S., Vadali, Gouri, Garces, Alejandra, Sutton, Jennifer N., Peterman, Scott, Byram, Gregory, Darbouret, Bruno, Pérusse, Joëlle R., Seidah, Nabil G., Coulombe, Benoit, Gobom, Johan, Portelius, Erik, Pannee, Josef, Blennow, Kaj, Kulasingam, Vathany, Couchman, Lewis, Moniz, Caje, Lopez, Mary F.

“…The aim of this study was to develop high-throughput, quantitative and highly selective mass spectrometric, targeted immunoassays for clinically important…”
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Population proteomics: the concept, attributes, and potential for cancer biomarker research by Nedelkov, Dobrin, Kiernan, Urban A, Niederkofler, Eric E, Tubbs, Kemmons A, Nelson, Randall W

“…This review outlines the concept of population proteomics and its implication in the discovery and validation of cancer-specific protein modulations…”
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High-Throughput Comprehensive Analysis of Human Plasma Proteins:  A Step toward Population Proteomics by Nedelkov, Dobrin, Tubbs, Kemmons A, Niederkofler, Eric E, Kiernan, Urban A, Nelson, Randall W

“…A high-throughput (HT) comprehensive analysis approach was developed for assaying proteins directly from human plasma. Proteins were selectively retrieved, by…”
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Proteomic characterization of novel serum amyloid P component variants from human plasma and urine by Kiernan, Urban A., Nedelkov, Dobrin, Tubbs, Kemmons A., Niederkofler, Eric E., Nelson, Randball W.

“…Serum amyloid P component (SAP) is a human plasma protein that has been widely studied for its influence on amyloid plaque formation and stabilization. SAP was…”
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Development of Recombinant-Based Mass Spectrometric Immunoassay with Application to Resistin Expression Profiling by Tubbs, Kemmons A, Kiernan, Urban A, Niederkofler, Eric E, Nedelkov, Dobrin, Bieber, Allan L, Nelson, Randall W

“…This report addresses the need for additional assays for human resistin (hRES) by developing a rational progression of the mass spectrometric immunoassay to…”
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High-Throughput Protein Characterization Using Mass Spectrometric Immunoassay by Kiernan, Urban A., Tubbs, Kemmons A., Gruber, Karl, Nedelkov, Dobrin, Niederkofler, Eric E., Williams, Peter, Nelson, Randall W.

“…A high-throughput mass spectrometric immunoassay system for the analysis of proteins directly from plasma is reported. A 96-well format robotic workstation was…”
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Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay by Kiernan, Urban A, Tubbs, Kemmons A, Nedelkov, Dobrin, Niederkofler, Eric E, Nelson, Randall W

“…Mass spectrometric immunoassay (MSIA) is a proteomics technology that combines the selectivity of affinity capture with the sensitivity and resolution of mass…”
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Transduction of biologically active motifs of the small heat shock‐related protein, HSP20, leads to relaxation of vascular smooth muscle by Flynn, Charles R., Komalavilas, Padmini, Tessier, Deron, Thresher, Jeffrey, Niederkofler, Eric E., Dreiza, Catherine M., Nelson, Randall W., Panitch, Alyssa, Joshi, Lokesh, Brophy, Colleen M.

“…ABSTRACT Activation of cyclic nucleotide‐dependent signaling pathways leads to phosphorylation of the small heat shock‐related protein, HSP20, on serine 16,…”
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Comparative Urine Protein Phenotyping Using Mass Spectrometric Immunoassay by Kiernan, Urban A, Tubbs, Kemmons A, Nedelkov, Dobrin, Niederkofler, Eric E, McConnell, Elizabeth, Nelson, Randall W

“…Reported here, human urine samples were analyzed for β-2-microglobulin (β2m), transthyretin (TTR), cystatin C, urine protein 1 (UP1), retinol binding protein…”
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Determination of β-2 Microglobulin Levels in Plasma Using a High-Throughput Mass Spectrometric Immunoassay System by Niederkofler, Eric E, Tubbs, Kemmons A, Gruber, Karl, Nedelkov, Dobrin, Kiernan, Urban A, Williams, Peter, Nelson, Randall W

“…A high-throughput mass spectrometric immunoassay (MSIA) system for the analysis of proteins directly from biological fluids is reported. A 96-well-format…”
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High-throughput affinity mass spectrometry by Kiernan, Urban A, Nedelkov, Dobrin, Niederkofler, Eric E, Tubbs, Kemmons A, Nelson, Randall W

“…Affinity mass spectrometry (AMS) is a proteomics approach for selectively isolating target protein(s) from complex biological fluids for mass spectrometric…”
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