Search Results - "Niederhuth, Chad E."
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Widespread natural variation of DNA methylation within angiosperms
Published in Genome Biology (27-09-2016)“…DNA methylation is an important feature of plant epigenomes, involved in the formation of heterochromatin and affecting gene expression. Extensive variation of…”
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The evolution of CHROMOMETHYLASES and gene body DNA methylation in plants
Published in Genome Biology (01-05-2017)“…The evolution of gene body methylation (gbM), its origins, and its functional consequences are poorly understood. By pairing the largest collection of…”
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On the origin and evolutionary consequences of gene body DNA methylation
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2016)“…In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively expressed genes (gene body methylation; gbM), but the origin and…”
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A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
Published in G3 : genes - genomes - genetics (01-09-2016)“…The nonmethylable cytosine analogs, 5-azacytidine and zebularine, are widely used to inhibit DNA methyltransferase activity and reduce genomic DNA methylation…”
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Covering Your Bases: Inheritance of DNA Methylation in Plant Genomes
Published in Molecular Plant (01-03-2014)“…Cytosine methylation is an important base modification that is inherited across mitotic and meiotic cell divisions in plant genomes. Heritable methylation…”
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Prenatal testosterone triggers long-term behavioral changes in male zebra finches: unravelling the neurogenomic mechanisms
Published in BMC genomics (06-03-2021)“…Maternal hormones, like testosterone, can strongly influence developing offspring, even generating long-term organizational effects on adult behavior; yet, the…”
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The Molecular Basis of Kale Domestication: Transcriptional Profiling of Developing Leaves Provides New Insights Into the Evolution of a Brassica oleracea Vegetative Morphotype
Published in Frontiers in plant science (05-03-2021)“…Morphotypes of are the result of a dynamic interaction between genes that regulate the transition between vegetative and reproductive stages and those that…”
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Transcriptional profiling of the Arabidopsis abscission mutant hae hsl2 by RNA-Seq
Published in BMC genomics (17-01-2013)“…Abscission is a mechanism by which plants shed entire organs in response to both developmental and environmental signals. Arabidopsis thaliana, in which only…”
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Maternal dominance contributes to subgenome differentiation in allopolyploid fishes
Published in Nature communications (15-12-2023)“…Teleost fishes, which are the largest and most diverse group of living vertebrates, have a rich history of ancient and recent polyploidy. Previous studies of…”
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The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis
Published in Cell reports (Cambridge) (17-02-2015)“…A critical aspect of mammalian gametogenesis is the reprogramming of genomic DNA methylation. The catalytically inactive adaptor Dnmt3L is essential to…”
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Letting Go is Never Easy: Abscission and Receptor- Like Protein Kinases
Published in Journal of integrative plant biology (01-12-2013)“…Abscission is the process by which plants discard organs in response to environmental cues/stressors, or as part of their normal development. Abscission has…”
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Regulatory dynamics distinguishing desiccation tolerance strategies within resurrection grasses
Published in Plant direct (01-12-2022)“…Desiccation tolerance has evolved recurrently in grasses using two unique strategies of either protecting or dismantling the photosynthetic apparatus to…”
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Putting DNA methylation in context: from genomes to gene expression in plants
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-01-2017)“…Plant DNA methylation is its own language, interpreted by the cell to maintain silencing of transposons, facilitate chromatin structure, and to ensure proper…”
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From Gigabyte to Kilobyte: A Bioinformatics Protocol for Mining Large RNA-Seq Transcriptomics Data
Published in PloS one (22-04-2015)“…RNA-Seq techniques generate hundreds of millions of short RNA reads using next-generation sequencing (NGS). These RNA reads can be mapped to reference genomes…”
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Intertwined evolution of plant epigenomes and genomes
Published in Current opinion in plant biology (01-06-2021)“…DNA methylation is found across eukaryotes; however, plants have evolved patterns and pathways of DNA methylation that are distinct from animals and fungi. DNA…”
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DNA methylation signatures of duplicate gene evolution in angiosperms
Published in Plant physiology (Bethesda) (03-08-2023)“…Abstract Gene duplication is a source of evolutionary novelty. DNA methylation may play a role in the evolution of duplicate genes (paralogs) through its…”
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Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus
Published in The New phytologist (01-04-2021)“…Summary Allopolyploidisation merges evolutionarily distinct parental genomes (subgenomes) into a single nucleus. A frequent observation is that one subgenome…”
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The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis
Published in Cell reports (Cambridge) (12-05-2015)Get full text
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Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2024)“…Abscission is the programmed separation of plant organs. It is widespread in the plant kingdom with important functions in development and environmental…”
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Single-molecule sequencing and optical mapping yields an improved genome of woodland strawberry (Fragaria vesca) with chromosome-scale contiguity
Published in Gigascience (01-02-2018)“…Although draft genomes are available for most agronomically important plant species, the majority are incomplete, highly fragmented, and often riddled with…”
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