Search Results - "Niederhuber, Matthew J"

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation by Riglar, David T, Giessen, Tobias W, Baym, Michael, Kerns, S Jordan, Niederhuber, Matthew J, Bronson, Roderick T, Kotula, Jonathan W, Gerber, Georg K, Way, Jeffrey C, Silver, Pamela A

“…An engineered commensal E. coli strain can function as a living diagnostic for a marker of inflammation in the murine gut for 200 days. Bacteria can be…”
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Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development by Nystrom, Spencer L, Niederhuber, Matthew J, McKay, Daniel J

“…How temporal cues combine with spatial inputs to control gene expression during development is poorly understood. Here, we test the hypothesis that the…”
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Hormone-dependent control of developmental timing through regulation of chromatin accessibility by Uyehara, Christopher M, Nystrom, Spencer L, Niederhuber, Matthew J, Leatham-Jensen, Mary, Ma, Yiqin, Buttitta, Laura A, McKay, Daniel J

“…Specification of tissue identity during development requires precise coordination of gene expression in both space and time. Spatially, master regulatory…”
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Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface by Naydich, Alexander D, Nangle, Shannon N, Bues, Johannes J, Trivedi, Disha, Nissar, Nabeel, Inniss, Mara C, Niederhuber, Matthew J, Way, Jeffrey C, Silver, Pamela A, Riglar, David T

“…Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to signals is a promising new approach for the diagnosis, treatment, and…”
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The SWI/SNF nucleosome remodeler constrains enhancer activity during Drosophila wing development by Niederhuber, Matthew J, Leatham-Jensen, Mary, McKay, Daniel J

“…Abstract Chromatin remodeling is central to the dynamic changes in gene expression that drive cell fate determination. During development, the sets of…”
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Mechanisms underlying the control of dynamic regulatory element activity and chromatin accessibility during metamorphosis by Niederhuber, Matthew J, McKay, Daniel J

“…[Display omitted] Cis-regulatory modules of metazoan genomes determine the when and where of gene expression during development. Here, we discuss insights into…”
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Superresolution microscopy of the β-carboxysome reveals a homogeneous matrix by Niederhuber, Matthew J, Lambert, Talley J, Yapp, Clarence, Silver, Pamela A, Polka, Jessica K

“…Carbon fixation in cyanobacteria makes a major contribution to the global carbon cycle. The cyanobacterial carboxysome is a proteinaceous microcompartment that…”
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Fine-Tuning Enhancer Activity in Development by Niederhuber, Matthew J

“…The development of a multicellular organism, from the origin of a single cell, depends on the manipulation of a shared genome to generate increasingly…”
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Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development by Nystrom, Spencer L, Niederhuber, Matthew J, McKay, Daniel J

“…How temporal cues combine with spatial inputs to control gene expression during development is poorly understood. Here, we test the hypothesis that the…”
Get full text

Engineered bacteria function in the mammalian gut as long term live diagnostics of inflammation by Riglar, David T, Giessen, Tobias W, Baym, Michael, Kerns, S Jordan, Niederhuber, Matthew J, Bronson, Roderick T, Kotula, Jonathan W, Gerber, Georg K, Way, Jeffrey C, Silver, Pamela A

“…Bacteria can be engineered to function as diagnostics or therapeutics in the mammalian gut but commercial translation of these technologies has been hindered…”
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