Search Results - "Nie, Yingjie"

Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer by Nie, Yingjie, He, Jiang, Shirota, Hidekazu, Trivett, Anna L, Yang, De, Klinman, Dennis M, Oppenheim, Joost J, Chen, Xin

“…Through the tumor necrosis factor (TNF) receptor type II (TNFR2), TNF preferentially activates, expands, and promotes the phenotypic stability of CD4 Foxp3…”
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PHF19 activates hedgehog signaling and promotes tumorigenesis in hepatocellular carcinoma by Xiaoyun, Shi, Yuyuan, Zi, Jie, Xing, Yingjie, Nie, Qing, Xie, Yuezhen, Deng, Haiguang, Xin

“…Aberrant activation of Hedgehog-Gli1 signaling and accumulation of Gli1 in hepatocellular carcinoma (HCC) are frequently observed. However, the mechanisms…”
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The state of the art of bispecific antibodies for treating human malignancies by Wang, Shuhang, Chen, Kun, Lei, Qi, Ma, Peiwen, Yuan, Andy Qingan, Zhao, Yong, Jiang, Youwei, Fang, Hong, Xing, Shujun, Fang, Yuan, Jiang, Ning, Miao, Huilei, Zhang, Minghui, Sun, Shujun, Yu, Zicheng, Tao, Wei, Zhu, Qi, Nie, Yingjie, Li, Ning

“…Bispecific antibodies (bsAb) that target two independent epitopes or antigens have been extensively explored in translational and clinical studies since they…”
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Alarmins and Antitumor Immunity by Nie, Yingjie, PhD, Yang, De, MD, PhD, Oppenheim, Joost J., MD

“…Abstract Purpose Alarmins are constitutively present endogenous molecules that essentially act as early warning signals for the immune system. We provide a…”
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Biomaterial-induced macrophage polarization for bone regeneration by Chen, Long, Yao, Zhicheng, Zhang, Siqin, Tang, Kuihan, Yang, Qiming, Wang, Yuanzheng, Li, Bohan, Nie, Yingjie, Tian, Xiaobin, Sun, Li

“…As the main target cells of immune regulation, macrophages play an important role in the bone regeneration process. Macrophages can be polarized into the M1…”
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Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors by Nie, Yingjie, Yang, De, Trivett, Anna, Han, Zhen, Xin, Haiyun, Chen, Xin, Oppenheim, Joost J.

“…Harnessing immune system to treat cancer requires simultaneous generation of tumor-specific CTLs and curtailment of tumor immunosuppressive environment. Here,…”
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KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma by Shen, Mao, Pan, Runsang, Lei, Shan, Zhang, Lu, Zhou, Changhua, Zeng, Zhirui, Nie, Yingjie, Tian, Xiaobin

“…Early metastasis is a hallmark of osteosarcoma (OS), a highly common type of malignant tumor. Members of the potassium inwardly rectifying channel family exert…”
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Hypoxia-Related Gene FUT11 Promotes Pancreatic Cancer Progression by Maintaining the Stability of PDK1 by Cao, Wenpeng, Zeng, Zhirui, Pan, Runsang, Wu, Hao, Zhang, Xiangyan, Chen, Hui, Nie, Yingjie, Yu, Zijiang, Lei, Shan

“…Hypoxia is associated with the development of pancreatic cancer (PC). However, genes associated with hypoxia response and their regulatory mechanism in PC…”
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Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice by Yang, Liqin, Xia, Zhixiong, Feng, Jianhua, Zhang, Menghuan, Miao, Pu, Nie, Yingjie, Zhang, Xiangyan, Hao, Zijian, Hu, Ronggui

“…Autism spectrum disorder (ASD) is a heritable neurodevelopmental disorder with the underlying etiology yet incompletely understood and no cure treatment…”
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UBQLN4 is an ATM substrate that stabilizes the anti‐apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma by Liu, Fang, Pan, RunSang, Ding, HongYu, Gu, LiLing, Yang, Yun, Li, ChuanYin, Xu, YongJie, Hu, Ronggui, Chen, Hui, Zhang, XiangYan, Nie, YingJie

“…ATM serine/threonine kinase (ATM; previously known as ataxia‐telangiectasia mutated) plays a critical role in maintaining genomic stability and regulates…”
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PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer by Yun, Mu, Yingzi, Li, Jie, Gao, Guanxin, Liu, Zimei, Zeng, Zhen, Cao, Zhi, Li, Yingjie, Nie, Lunquan, Sun, Tao, Chen, Yuezhen, Deng, Chengzhi, Zhou

“…Resistance to radiotherapy is frequently observed in the clinic and leads to poor prognosis of non-small cell lung cancer (NSCLC). How to overcome resistance…”
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Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model by Jing, Qianyu, Wan, Quan, Nie, Yujie, Luo, Junqian, Zhang, Xiangyan, Zhu, Lan, Gui, Huan, Li, Linzhao, Wang, Chenglv, Chen, Shuanghui, Wang, Mengjiao, Yuan, Haohua, Lv, Hang, Pan, Runsang, Jing, Qianjun, Nie, Yingjie

“…As psychoneuroimmunology flourishes, there is compelling evidence that depression suppresses the anti-tumor immune response, promotes the progression of…”
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FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squamous cell carcinoma by Chen, Tao, Wang, Fei, Wei, Shupei, Nie, Yingjie, Zheng, Xiaotao, Deng, Yu, Zhu, Xubin, Deng, Yuezhen, Zhong, Nanshan, Zhou, Chengzhi

“…FGFR is considered an important driver gene of lung squamous cell carcinoma (LSCC). Thus, identification of the biological events downstream of FGFR is…”
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Characterization of the transcriptional response of Candida parapsilosis to the antifungal peptide MAF-1A by Cheng, Rong, Li, Wei, Sample, Klarke M, Xu, Qiang, Liu, Lin, Yu, Fuxun, Nie, Yingjie, Zhang, Xiangyan, Luo, Zhenhua

“…Candida parapsilosis is a major fungal pathogen that leads to sepsis. New and more effective antifungal agents are required due to the emergence of resistant…”
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Virus isolation and genotype identification of human respiratory syncytial virus in Guizhou Province, China by Zhao, Ting, Ye, Zhixu, Wang, Binlin, Cui, Yuxia, Nie, Yingjie, Yang, Bin, Chen, Kun, Zhang, Hua, Hu, Fangfang, Yu, Fuxun

“…To investigate the genetic variation and molecular epidemiology characteristics of Human Respiratory Syncytial Virus (HRSV) in Guizhou Province, nasopharyngeal…”
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Comparison of enzyme-linked immunosorbent assay systems using rift valley fever virus nucleocapsid protein and inactivated virus as antigens by Yu, Fuxun, Adungo, Ferdinard, Konongoi, Samson Limbaso, Inoue, Shingo, Sang, Rosemary, Ashur, Salame, Kwallah, Allan Ole, Uchida, Leo, Buerano, Corazon C, Mwau, Matilu, Zha, Yan, Nie, Yingjie, Morita, Kouichi

“…Rift Valley Fever (RVF) is a mosquito-borne viral zoonosis. To detect RVF virus (RVFV) infection, indirect immunoglobulin G (IgG) and immunoglobulin M (IgM)…”
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Abstract 2468: Increased expression of snoRNA in the tumor vasculature by Sample, Klarke M., Nie, Yingjie, Bicknell, Roy

“…Abstract The tumor microenvironment has long been known to cause the differential expression of many genes within the endothelial cells that comprise the tumor…”
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Psychological distress influences lung cancer: Advances and perspectives on the immune system and immunotherapy by Gui, Huan, Chen, Xulong, Li, Linzhao, Zhu, Lan, Jing, Qianyu, Nie, Yingjie, Zhang, Xiangyan

“…•Catecholamine- and neurotransmitter-activated signaling pathways from PD acts onimmune and tumor cells.•Mechanistically, β-AR signaling pathways altered lung…”
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Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence by Wei, Shupei, Liu, Lili, Chen, Zhiyu, Yin, Wenli, Liu, Yingzi, Ouyang, Qianying, Zeng, Feiyue, Nie, Yingjie, Chen, Tao

“…Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have…”
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Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer by Zhu, Lan, Zhang, Xiangyan, Chen, Xin, Yang, De, Nie, Yujie, Pan, Runsang, Li, Linzhao, Wang, Chenglv, Gui, Huan, Chen, Shuanghui, Jing, Qianyu, Wang, Mengjiao, Nie, Yingjie

“…Immunotherapy is the new approach for cancer treatment that can be achieved through several strategies, one of which is dendritic cells (DCs) vaccine therapy…”
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